We Need Help!

[alexx6520]

I'll try to keep this short but informative. I have two boys, our youngest (3) has eosinophilic gastrointestinal disease and lots of food allergies. His symptoms at diagnoses were almost all opposite our 4 1/2 year old.

My oldest has been constipated since he was several months old although he never has hard bm's he just doesn't go often. He gets very bloated, distended, and irritable. He had a period of diarrhea when he was two that lasted for months. He has some food and environmental allergies but mostly seafood. He is currenlty eating dairy and wheat because they didn't show positive on any testing (yet). Family history of 2 possible celiacs, 1 diagnosed by a dermatologist, the other on his own throgh trial and error. Most recent bloodwork shows HLA DQ2 positive and gliadin igg is 7, gliadin iga is 2 (quest) and elevated creatine although probably not related. GI has once again said no celiac (yet) because gliadin levels would be over 20 per quest labs.

My question is...shouldn't his gliadin numbers be 0? I sort of thought the antibodies are either there or there not. I found something from the children's hospital of minnestoa that says under 7 is negative, 7-10 is equivocal, and over 10 is positive. I'm not certain it's the same test and I don't know what unit of measurement quest uses. The children's hospital says ml. I tried to call quest labs to ask if they account for a person's age but couldn't get an answer.

I know I can do a gluten free trial and probably get the answers we need but he also has a lot of other bizzare symptoms and if they are not related to celiac, I need to keep looking for answers. He experiences bone pain in arms and legs, fatigue, bed wetting, occasional gray hairs, eczema, headaches, and frequent resp. infections. I'm going to request labs for type 1 diabetes but I would love some feedback on our crazy kid. Thanks!

[psawyer]

My question is...shouldn't his gliadin numbers be 0? I sort of thought the antibodies are either there or there not.

Welcome to the board.

The confusion arises from the fact that the tests are not perfect, and can respond at a low level to things other than the things for which they are testing. That is why there is a reference range for each test, and that range varies from lab to lab.

[Dixiebell]

Welcome to the forum alexx.

Here is the list of over 300 Signs, Symptoms, Associated Disorders and Complications directly or indirectly resulting from celiac disease and gluten sensitivity.

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