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Different Reactions At Different Times?


Aseyan

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Aseyan Newbie

Hi Everyone,

My name is Jennie and I am new to this forum. I've been feeling pretty terrible for a while now and have been doing an elimination diet to see if we could come up with what was causing me problems. Recently I narrowed it down to a gluten intolerance but we just need to figure out if its a straight intolerance or celiac. I wouldn't be surprised if it were celiac simply because I've had a thyroid autoimmune and I know I'm more susceptible to different autoimmunes.

I do have a question however. In my elimination process, I've noticed that my reactions as less severe in the evening. For example, Monday night I had couscous and felt 'okay'. Tuesday for lunch I had the same meal and felt like death.

Why is that? I'm actually second guessing myself that gluten is my issue because of this but at the same point, its the only constant in feeling terrible. I get the bloating, abdominal pain, tummy troubles, mind fog, headaches, fatigue etc.

What do you think?

Thanks,

Jennie


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pain*in*my*gut Apprentice

Hi Everyone,

My name is Jennie and I am new to this forum. I've been feeling pretty terrible for a while now and have been doing an elimination diet to see if we could come up with what was causing me problems. Recently I narrowed it down to a gluten intolerance but we just need to figure out if its a straight intolerance or celiac. I wouldn't be surprised if it were celiac simply because I've had a thyroid autoimmune and I know I'm more susceptible to different autoimmunes.

I do have a question however. In my elimination process, I've noticed that my reactions as less severe in the evening. For example, Monday night I had couscous and felt 'okay'. Tuesday for lunch I had the same meal and felt like death.

Why is that? I'm actually second guessing myself that gluten is my issue because of this but at the same point, its the only constant in feeling terrible. I get the bloating, abdominal pain, tummy troubles, mind fog, headaches, fatigue etc.

What do you think?

Thanks,

Jennie

Hi Jennie (I'm Jenny)! :D I have found that there really is no direct correlation to my onset and/or severity of symptoms and when I eat gluten. I can have a bagel one morning and be fine, and the next morning I eat one I am blown up like a balloon. Or, I can eat pasta for lunch and feel drunk and sickly tired all afternoon, and the next day I only get really gassy after the same meal. Sometimes I feel sick within hours, sometimes it's more like a day later. Isn't it fun being gluten intolerant? :blink:

There is also the possibility that you are intolerant to other things as well, like lactose or soy (which is common for Celiacs). Add those into the mix and you've really got a mess.... :blink:

Have you had the blood tests yet? Keep in mind that you need to be eating gluten for at least 4-6 weeks before you get tested so that the results will be accutate.

Aseyan Newbie

Hi Jennie (I'm Jenny)! :D I have found that there really is no direct correlation to my onset and/or severity of symptoms and when I eat gluten. I can have a bagel one morning and be fine, and the next morning I eat one I am blown up like a balloon. Or, I can eat pasta for lunch and feel drunk and sickly tired all afternoon, and the next day I only get really gassy after the same meal. Sometimes I feel sick within hours, sometimes it's more like a day later. Isn't it fun being gluten intolerant? :blink:

There is also the possibility that you are intolerant to other things as well, like lactose or soy (which is common for Celiacs). Add those into the mix and you've really got a mess.... :blink:

Have you had the blood tests yet? Keep in mind that you need to be eating gluten for at least 4-6 weeks before you get tested so that the results will be accutate.

I did get the blood test done this morning. I only eliminated gluten for 2 days before adding it back in (it was actually an inadvertent elimination, I wasn't scheduled to eliminate until later this week for a few weeks). I do also have a sensitivity to lactose but soy hasn't been too bad for me that I'm aware of. We'll see what the blood test comes back with but I'm not sure if I want to go as far as the biopsy is concerned. I'll have to talk with my doc about that one :)

Thanks!

Jennie

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
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      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
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