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Ttg Igg Test Results

NJceliac

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NJceliac Apprentice
NJceliac
Posted

I was diagnosed with celiac with positive serology results as well as a positive biopsy after a workup for premenopausal osteoporosis. I also have IgA deficiency so most of the serology tests are not able to be used to follow the antibody levels. On this forum I have seen some people give specific values to tTG antibody results even if they are greater then 100. The lab I used only posts >100 and does not give a value. My question is for those of you who get tTG IgG ab levels drawn and get a specific value i.e., 295 instead of a value >100, which lab was the bloodwork sent to?

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beachbirdie Contributor
beachbirdie
Posted

I was diagnosed with celiac with positive serology results as well as a positive biopsy after a workup for premenopausal osteoporosis. I also have IgA deficiency so most of the serology tests are not able to be used to follow the antibody levels. On this forum I have seen some people give specific values to tTG antibody results even if they are greater then 100. The lab I used only posts >100 and does not give a value. My question is for those of you who get tTG IgG ab levels drawn and get a specific value i.e., 295 instead of a value >100, which lab was the bloodwork sent to?

Mine was done by Labcorp, and I got a specific value for my TtG IgG. The ranges were very different from yours however.

I'm not sure the exact value matters. If you came in positive, you are positive. The degree of damage does not necessarily correlate with the number of antibodies, some people have low or no antibodies and still have lots of damage, others have high levels of antibodies and have spottier damage.

sa1937 Community Regular
sa1937
Posted

I was diagnosed with celiac with positive serology results as well as a positive biopsy after a workup for premenopausal osteoporosis. I also have IgA deficiency so most of the serology tests are not able to be used to follow the antibody levels. On this forum I have seen some people give specific values to tTG antibody results even if they are greater then 100. The lab I used only posts >100 and does not give a value. My question is for those of you who get tTG IgG ab levels drawn and get a specific value i.e., 295 instead of a value >100, which lab was the bloodwork sent to?

My celiac panel was done by Quest and it indicated a tTG IGA Ab >100 with >8 being positive. I am not IGA deficient.

  • 2 months later...
badgrammer Newbie
badgrammer
Posted

Hello! I am new to the forum and I am wondering if someone can help me determine my results...? I just had blood work done through LabCorp to test my IgG and IgA panels, but I unfortunately don't understand what it means. If anyone can make heads or tails of what this might mean or if you can point me in the right direction where I can find out more, I'd greatly appreciate it. Thank you!!

2

Negative

Weak Positive

11-58 20-101 44-189 62-236 77-278 91-414

Deamidated Gliadin Abs, IgA

Deamidated Gliadin Abs, IgG

t-Transglutaminase (tTG) IgA

N units 0-19

0 - 19

20 - 30

Moderate to Strong Positive >30

3 N

Negative 0 - 19 Weak Positive 20 - 30 Moderate to Strong Positive >30

<2 N

Negative 0 - 3 Weak Positive 4 - 10 Positive >10

units 0-19

U/mL 0-3

U/mL 0-5

. Tissue Transglutaminase (tTG) has been identified

as the endomysial antigen. Studies have demonstr- ated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.

t-Transglutaminase (tTG) IgG <2 N

Negative 0 - 5 Weak Positive 6 - 9 Positive >9

GottaSki Mentor
GottaSki
Posted

Is this exactly how it was written? Very confusing, but I THINK the capital N's are your results - hard to tell which test correlates to which result. If I am correct this would mean all your tests were negative.

Please double check this is how it was written - maybe someone else will have a better take on it.

frieze Community Regular
frieze
Posted

This is one of the most confusing lab reports I have ever seen! I am hoping part of the problem is formating on the computor. I am thinking that the deaminated IgG is a weak positive. and i don't see a total IgA in this mess.

If i am right, you are positive on the THE most sensitive test for celiac. good luck

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    • trents
      Taking Probiotics but Still Getting Sick After Gluten – Advice?

      By trents · Posted

      The blood tests you had done are not the main ones. The two main ones are the "Total IGA" (to check for IGA deficiency) and the "TTG-IGA". Current guidelines for the "gluten challenge" when people have been gluten free for a significant time period are the daily consumption of at least10g of gluten (about the amount in 4-6 slices of wheat bread) for at least two weeks leading up to the day of the blood draw. That should give you some perspective.
    • Xravith
      Taking Probiotics but Still Getting Sick After Gluten – Advice?

      By Xravith · Posted

      Thank you, really.  I took a test for DGP-IgA and DGP-IgG. Effectively, it is not enough to discard Celiac Disease. I was consuming gluten until then, I only started gluten-free some days ago, when the symptoms became horrible and now I feel considerably better, which is a second confirmation that gluten is the main problem. It's been more than 4 years I have the same suspect, when I first thought gluten was causing me problems, I made a gluten-free diet for a year, I felt really good as never before. However, neither I or my parents were well informed about Celiac disease, so none of us tried to make further exams. My father suffer digestive problems and other members of my family as well. Unfortunately, no one have ever been tested for Celiac disease. I'll have to restart eating gluten in the next weeks, so I can make a serious blood test in laboratory, hopefully between two or three months.
    • trents
      Taking Probiotics but Still Getting Sick After Gluten – Advice?

      By trents · Posted

      As Scott said, in order for celiac disease testing to be valid, you need to be eating generous amounts of gluten on a regular basis for weeks or months before the blood draw. The blood tests are designed to detect antibodies that the immune system produces in response to the ingestion of gluten. It takes time for them to build up in the blood to detectable levels.
    • Scott Adams
      Taking Probiotics but Still Getting Sick After Gluten – Advice?

      By Scott Adams · Posted

      Based on what you've described, it is absolutely crucial that you pursue further medical exams for Celiac Disease and related conditions with a gastroenterologist. Your symptoms—especially the worsening fatigue, loss of muscle mass, neurological symptoms like migraines, and palpitations, coupled with being underweight—are significant red flags that extend beyond typical IBS. The negative home test is not reliable, particularly given your concern about sample contamination and the fact that you were likely not consuming sufficient gluten at the time for the test to be accurate, which is a common issue. While probiotics like Bifidobacterium Infantis can support gut health, they cannot resolve an autoimmune response to gluten or heal intestinal damage caused by Celiac Disease. Your declining blood test results, even if still "in range," further indicate a trend that needs a doctor's investigation. Please do not hesitate to seek a specialist; a formal diagnosis is the first step toward getting the correct treatment, allowing your body to heal, and finally addressing your weight and overall health concerns. This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. One test that always needs to be done is the IgA Levels/Deficiency Test (often called "Total IGA") because some people are naturally IGA deficient, and if this is the case, then certain blood tests for celiac disease might be false-negative, and other types of tests need to be done to make an accurate diagnosis. The article includes the "Mayo Clinic Protocol," which is the best overall protocol for results to be ~98% accurate.    
    • Scott Adams
      Buckwheat

      By Scott Adams · Posted

      I would only add that cross contamination with wheat may still be a possibility, so it's still best to seek out buckwheat that is labeled "gluten-free."
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