Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Igg/iga/ttg

Mom22

Recommended Posts

Mom22 Apprentice
Mom22
Posted

Both our daughter and son have been diagnosed with celiac disease this year via biopsies. Both were asymptomatic, but our son was experiencing constipation which warranted further testing. It was only through a diligent pediatrician did he order several blood screens and one was the gluten enterpathy and that started the ball rolling. He had a biopsy, came back positive, then his sister, had blood work, was elevated, had a biopsy which was inconclusive and had a second opinion by Dr. Fasano of her biopsy slides, which was positive for celiac. I had bloodwork done and all screens were negative. My husband had bloodwork done and also the HLA test and he does have the DQ2 & DQ8 genes. His IGG (112) and IGA (27) are elevated, but the TTG (4) is within normal limits. My husband is seeing Dr. Fasano in September. Due to knowing that the celiac came through my husband's side of the family, we advised his parents to have the initial blood screen done. My mother in law has had her test and the nurse practioner of her family physician called and said she was negative. She didn't have any of the #'s of the results. I asked her if she could get a copy and mail it to me only because initially, my husband's dr. said he was negative, but then when we received a copy of the results, we pursued further testing. I am a work in progress as far as my knowledge of celiac goes, but her results, I think may warrant further testing or seeing a specialist. Please tell me if I am wrong as I don't want to alarm my mother in law. I realize my mother in law could be a carrier and the celiac has not and may never develop in her. My father in law hasn't had his blood work done yet. What do you think?

My mother in law's results.

IGG: 27.7

IGA 42.1

TTG 6

Thanks for an light you can shed on this.

Mom 2 2 celiac children

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mat4mel Apprentice
mat4mel
Posted

I am totally confused.. all of those results sound positive for celiac to me.. why would they say they were negative?

Mom22 Apprentice
Mom22
Posted
  • Author

Thanks. You just confirmed what I have been thinking all along. I thought the same thing, but they are telling my mother-in-law that her results are negative. I am thinking otherwise. Thank you for your input.

lovegrov Collaborator
lovegrov
Posted

Also sounds positive to me.

richard

gf4life Enthusiast
gf4life
Posted

Here is my interpretation. See, my doctors office considers (wrongly) anything under 30 to be negative on the IgA and IgG, and under 20 negative on the tTg. So my interpretation is that they are ignoring the obviously positive IgA, since they seem to think the other two are negative.

The problem with this is that the blood tests are NOT as accurate as the doctors think and with even one of them showing positive then it is most likely celiac. Either further testing or a trial gluten-free diet is in order, but I don't recommend the diet until after the biopsy, assuming a biopsy might happen in the future. I personally chose Enterolab after the doctors insisted for two years that my tests were all negative, and the biopsy performed after being gluten-free was negative. Enterolab showed that I not only had the genes, but was producing positive level antibodies to gluten and casein in my intestines, but I did not have severe damage to my intestines (probably since they healed partially while I was gluten-free!).

I hope your mother-in-law doesn't have to be sick for long. Please urge her to get more testing done (or try the diet).

God bless,

Mariann

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      130,536
    • Most Online (within 30 mins)
      7,748
    CCST
    Newest Member
    CCST
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Fabrizio
      Kan-101

      By Fabrizio · Posted

      Thanks for your article. 
    • NCalvo822
      Newly Diagnosed

      By NCalvo822 · Posted

      Thank you.  Very helpful.
    • knitty kitty
      Newly Diagnosed

      By knitty kitty · Posted

      Migraines can be caused by Thiamine deficiency.  Thiamine is a B vitamin that becomes depleted quickly because it can't be stored long.  All the  B vitamins work together to make energy, ATP, which is used to fuel all the cell activity.  Without Thiamine, the energy production cycle doesn't even get started.   There's studies done on mice showing thiamine deficiency affects the offspring of thiamine deficient mothers and fathers.  The offspring have fewer thiamine receptors and are prone to becoming thiamine insufficient quickly.  They have a higher metabolic need for thiamine.  Supplementing with extra thiamine helped them  tremendously. Migraines have run in my family for several generations, too.  Once I started taking TTFD, a form of thiamine that can enter cells without using thiamine transporters, my migraines have vanished.  TTFD is tetrahydrofurfuryl disulfide. Benfotiamine is another form that can improve migraine frequency, too. Thiamine is safe and nontoxic even in high doses.  There is no upper limit because thiamine has never caused a death even in high doses.  It is excreted via kidneys if not needed or not absorbed.
    • knitty kitty
      Lymphocytic Colitis with Celiac

      By knitty kitty · Posted

      Thank you, @Oldturdle, I greatly appreciate that.  I've always been a curious kitty.  I wanted to figure out why I didn't feel well because I knew it wasn't all in my head like they told me.  It pleases me to be able to help others in the same boat. Yes, alcohol prevents the absorption of thiamine and stops thiamine from working properly.  This can lead to Wernicke's Encephalopathy and Korsakoff syndrome, where thiamine deficiency severely affects brain function.  Doctors are trained to look for the triad of symptoms: opthalmoplegia (nystagmus), ataxia, and altered mental state.  However, not all people present with all three symptoms.  Many (80%) don't get diagnosed until their autopsy.   Alcohol has to be processed through the liver.  If there's insufficient thiamine, Alcoholic Fatty Liver develops.  In thiamine insufficiency, calories are turned into fat and stored in the liver instead of being turned into fuel ATP for the body.  Alcohol also prevents absorption of calories from food and other nutrients.   Non-alcoholic Fatty Liver can develop in nonalcoholics, storing excess calories as fat in the liver.  However, excess calories can also be turned into fat and stored in the abdomen, hence the increase in obesity.   In Celiac disease, we don't absorb sufficient nutrients like thiamine from our food.  If we eat a diet high in carbohydrates, we can run out of vitamins like thiamine and the other Bs needed to turn those calories into fuel ATP.  For every extra thousand calories of carbohydrates consumed, our bodies require 500 to 1000 mg of additional thiamine to process them into fuel, ATP,  the "bitcoin" of energy in our bodies.   Wernicke's encephalopathy can occur in non-alcoholic people, but doctors can miss the symptoms because the patient doesn't drink, and doesn't have all three symptoms of the classic Triad of symptoms seen in Wernicke-Korsakoff syndrome.  My doctors failed to diagnose me with thiamine deficiency, Wernicke's Encephalopathy,  because I didn't drink alcohol, although I had ataxia and an altered mental state.   Doctors don't think outside the box!   I went home and took thiamine.  I had improvement in my symptoms within an hour.  High doses of thiamine are required to correct Thiamine deficiency.  Thank God I had studied nutrition, microbiology, and the research of Dr. Derrick Lonsdale and Dr. Chandler Marrs.  ("Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition" is Drs. Lonsdale and Marrs' book.).  And I've kept learning and sharing that knowledge to help others.   It's wonderful you've been supplementing with vitamins so long!  Don't worry about the bright yellow urine.  That's excess Riboflavin B 2.  Interesting note, Riboflavin glows under black light!  Those lights used to detect where pets have soiled outside of the box, that's the Riboflavin in urine glowing.  Riboflavin can be put in sugar syrup when making rock candy and it will glow under black light.  Fun for Halloween. I hope you feel better, @Oldturdle.  If I can be of further help anytime, you can send a personal message here.  Thanks for reading my posts.  P.S. Thiamine deficiency and Wernicke's Encephalopathy are completely reversible if treated promptly with high dose Thiamine.
    • DebJ14
      Newly Diagnosed

      By DebJ14 · Posted

      Migraines ran in my family, on my father's side.  All of my female first cousins on that side, and our grandmother suffered from Migraines.  Grandmother died in 1984 so we do not know if she ever would have been diagnosed with celiac disease. However, all 4 of us cousins were diagnosed with celiac disease between 2003 and 2007.  The dermatitis herpetiformis rash is a blistery, super itchy rash.  When they do the biopsy they take it from non-involved skin that is next to the rash.  If done wrong, the results may not be accurate.  Have you ever had one done? In that case, I agree that maybe she has you still on gluten for a biopsy.  But, if she has not ordered it nor referred you to a gastroenterologist, then I would question her advice.  
×
×
  • Create New...