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Negative Test?

taynichaf

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taynichaf Contributor
taynichaf
Posted

I'm just so scared that I will be one of the many people that test negative for celiacs, even if I do have it..so what would be the next step??

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kareng Grand Master
kareng
Posted

The newer tests re quite reliable.

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Is it possible to have a negative blood test, but a positive biopsy?

While rare, it is possible to have a negative blood test and still have celiac disease. tTG sensitivity is approximately 98%, which means that 2% of all celiacs may have a normal tTG level. Sometimes tTG antibodies are not produced enough to show up in the blood stream and can only be detected in the intestinal mucosa by special means.

IgA deficiency is a reason why you might have a negative blood test, but a positive biopsy.

Further medical evaluation is important for anyone still experiencing symptoms in order to establish the diagnosis or to rule out celiac disease as a part of establishing another diagnosis. In some cases, celiac disease is the wrong diagnosis as such conditions as Crohn’s Disease and food protein allergy share many of the same symptoms.

nvsmom Community Regular
nvsmom
Posted

That doesn't happen often. I think what is more common is that one will have negative celiac tests yet have non-celiac gluten intolerance (NCGI) which requires the same adherence to the gluten-free diet.

 

Good luck.

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      thank you RMJ! That is very helpful advice. Good to know we aren’t crazy if we don’t do the endoscopy. We are going to try the gluten free and see how symptoms and levels improve.    thank you Wheatwacked (love the username lol) that is also reassuring. Thankfully she has an amazing and experienced pediatrician. And yesss I forgot to mention the poop! She has the weirdest poop issues.    How long did it take y'all to start seeing improvement in symptoms? 
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