Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Question About Test Results

formygirl

Recommended Posts

formygirl Rookie
formygirl
Posted

I have a doctor's interpretation of these results, but I'm curious about what others with experience would say about these:  

 

gliadin (deaminated) abs

     gliadin, iga        9            standard range <20

     gliadin, igg        48          standard range <20

 

IGA    157    standard range 78-391

 

Transglutiminase Ab, IgA      17   standard range <20

 

Endomysial Ab, IgA  <1:10       standard range DLT10

 

 

Thanks in advance.

 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


nvsmom Community Regular
nvsmom
Posted

What appears to be your DGP IgG is positive. It is often a good early test for the disease, unlike the EMA Iga which requires a fair bit of damage to register a positive - yours appears negative.

 

I would say it looks like you could be a celiac. DGP tests are pretty specific and sensitive to celiac. Yours is over double the accepted range.

 

Now... many doctors will say you could have a gluten intolerance with just one test positive and hum and hah over actually saying "celiac disease". I'm curious what your doctor said - I feel like I'm being tested! :wacko:

powerofpositivethinking Community Regular
powerofpositivethinking
Posted

I feel like I'm looking at my results  :)  I also had only a positive DGP igg, and negative everything else, and I am not igA deficient.  I had an EGD with 8 biopsies, and since they came back normal, my GI diagnosed me with gluten intolerance.  I am also vitamin D and K deficient, and low in potassium.  I still say if it was only gluten intolerance, why is my body creating antibodies against food  <_<

 

interested to hear what your doctor's take on it was!

I have a doctor's interpretation of these results, but I'm curious about what others with experience would say about these:  

 

gliadin (deaminated) abs

     gliadin, iga        9            standard range <20

     gliadin, igg        48          standard range <20

 

IGA    157    standard range 78-391

 

Transglutiminase Ab, IgA      17   standard range <20

 

Endomysial Ab, IgA  <1:10       standard range DLT10

 

 

Thanks in advance.

formygirl Rookie
formygirl
Posted
  • Author

These were my results... I was tested after my three year old was diagnosed.  She said the IGg is generally over sensitive and since the total IGa was low (and all other results), we could "ignore" the elevated number.  Hmmm...

mushroom Proficient
mushroom
Posted

These were my results... I was tested after my three year old was diagnosed.  She said the IGg is generally over sensitive and since the total IGa was low (and all other results), we could "ignore" the elevated number.  Hmmm...

 

Your total IgA is normal, not low.  If it were low (i.e., did not fall within the normal range) then the other IgA tests would not be valid.

 

I would not, however, ignore the positive IgG.  We have posters on the board whose only positive blood test was DGP IgG, and they were positive on biopsy.

formygirl Rookie
formygirl
Posted
  • Author

Yeah, this was from my daughter's Gastro doc. I planned on asking my doctor about the results. I am asymptomatic... but I know that doesn't mean I'm negative for Celiac.

This is the quote on the test:

The Gliadin IgG is generally over sensitive. We get it when screening because often patients with celiac disease have a low serum IgA and all of the other markers depend on that level. Since your total serum IgA was normal we can ignore the elevated IgG.

My question: Is there anything else it could indicate besides Celiac?

mushroom Proficient
mushroom
Posted

Yeah, this was from my daughter's Gastro doc. I planned on asking my doctor about the results. I am asymptomatic... but I know that doesn't mean I'm negative for Celiac.

This is the quote on the test:

The Gliadin IgG is generally over sensitive. We get it when screening because often patients with celiac disease have a low serum IgA and all of the other markers depend on that level. Since your total serum IgA was normal we can ignore the elevated IgG.

My question: Is there anything else it could indicate besides Celiac?

 

The DGP has, I believe, about 99% specificity for celiac disease.  And it is, as the doctor said, a very sensitive test.  It will often pick the disease up in its early stages before there is much intestinal damage. 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


powerofpositivethinking Community Regular
powerofpositivethinking
Posted

so far no one has been able to come up with a reason for a raised DGP score besides celiac.  here's a thread I started regarding it

https://www.celiac.com/forums/topic/100245-other-known-causes-of-high-dgp-igg-besides-celiac/

 

 


My question: Is there anything else it could indicate besides Celiac?

nvsmom Community Regular
nvsmom
Posted

I think your doctor's explanation of discounting the DGP IgG test was ... pretty lame. Why would they run it if they are just going to ignore it?  I think some doctors just don't like to label it as celiac because they think the diet is "too hard" which is total hogwash - there are quite a few foods out there that would be harder to get out of our diet if you eat any processed foods at all... like corn!  Eek!

 

The DGP is a really good test. Sensitive is a GOOD thing.... And that was a gastro who said all that, eh? Sheesh.

formygirl Rookie
formygirl
Posted
  • Author

Yeah, it was the pediatric gastro who said this.  She had no qualms about doing an endo and diagnosing my daughter, so I don't think she would necessarily be hesitant with me, but who knows.  I don't really know where to go with this.  Since she is not really my doctor, and i'm not under a doctor's care right now, I don't know how to follow up.  I think I will bring it up to her when my daughter has her follow up soon.

Deaminated Marcus Apprentice
Deaminated Marcus
Posted

Yeah, it was the pediatric gastro who said this.  She had no qualms about doing an endo and diagnosing my daughter, so I don't think she would necessarily be hesitant with me, but who knows.  I don't really know where to go with this.  Since she is not really my doctor, and i'm not under a doctor's care right now, I don't know how to follow up.  I think I will bring it up to her when my daughter has her follow up soon.

 

Your daughter has Celiac !

Doesn't that doctor know that Celiac is hereditary?   :huh:

That should be proof enough for the doctor: close family member + high DGP-IgG = do an endoscopy to confirm.

  (+ test the father)   

formygirl Rookie
formygirl
Posted
  • Author

father and sister were tested, and she said they were fine.  i saw sisters results... all in normal range, but i didn't see dad's... for all i know it is like mine was.  I have a follow up with her at the end of May for my daughter, so I will talk with her about it at that time.  thanks!

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. cristiana
      - cristiana replied to KathyR37's topic in Coping with Celiac Disease
      4

      New here

      Hi @KathyR37 and a very warm welcome here. I am so very sorry that you are going through all of this. I just wanted to check, have you ever been tested for any other gastrointestinal conditions? Cristiana
    2. trents
      - trents replied to KathyR37's topic in Coping with Celiac Disease
      4

      New here

      @KathyR37, I would suspect that in addition to gluten intolerance, you have other food intolerances/sensitivities. This is very common in the celiac community. The most common offenders are oats, dairy, soy, corn and eggs with dairy and oats being the big two. Have you considered this? Have you tried keeping a food diary to detect patterns?
    3. Theresa2407
      - Theresa2407 replied to Theresa2407's topic in Gluten-Free Foods, Products, Shopping & Medications
      2

      Probiotics

      thank you for your advice. I have always taken them and I use Stonehedge because they are in a glass bottle, but don't have to be refrigerated. I also like they are 3rd party tested and state gluten free. But you never know if something better has come alone over the years.
    4. KathyR37
      - KathyR37 replied to KathyR37's topic in Coping with Celiac Disease
      4

      New here

      Thank you for your response. I have already learned about the info you sent but i appreciate your effort. I am the only one in my family cursed by this disease. I have to cook for them too. I make sure that my utensils are free of gluten and clean after using them for other food. I use non-porous pots and pans and gloves when cooking for them. One huge problem...
    5. Scott Adams
      - Scott Adams replied to KathyR37's topic in Coping with Celiac Disease
      4

      New here

      What you've described—the severe weight loss, the cycle of medications making things worse, and the profound fear of eating before leaving the house—is a heavy burden to carry for 15 years. It is absolutely not your fault. While everyone's journey with celiac is different, the struggles with the learning curve, social isolation, and dietary grief are fee...
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,817
    • Most Online (within 30 mins)
      7,748
    sleuth
    Newest Member
    sleuth
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • cristiana
      New here

      By cristiana · Posted

      Hi @KathyR37 and a very warm welcome here.  I am so very sorry that you are going through all of this. I just wanted to check, have you ever been tested for any other gastrointestinal conditions? Cristiana  
    • trents
      New here

      By trents · Posted

      @KathyR37, I would suspect that in addition to gluten intolerance, you have other food intolerances/sensitivities. This is very common in the celiac community. The most common offenders are oats, dairy, soy, corn and eggs with dairy and oats being the big two. Have you considered this? Have you tried keeping a food diary to detect patterns?
    • Theresa2407
      Probiotics

      By Theresa2407 · Posted

      thank you for your advice.   I have always taken them and I use Stonehedge because they are in a glass bottle, but don't have to be refrigerated.  I also like they are 3rd party tested and state gluten free. But you never know if something better has come alone over the years.
    • KathyR37
      New here

      By KathyR37 · Posted

      Thank you for your response. I have already learned about the info you sent but i appreciate your effort. I am the only one in my family cursed by this disease. I have to cook for them too. I make sure that my utensils are free of gluten and clean after using them for other food. I use non-porous pots and pans and  gloves when cooking for them. One huge problem I have is a gag reflex out of this world and if something doesn't taste good it is not going down. Most commercially made breads and such taste like old cardboard.Pastas are about the same. I did find one flour that I like and use it regularly, but it is so expensive! All gluten free food is way more expensive. I only eat twice a day because I cannot afford to buy all that. We live on a very low income so my food purchases are quite limited.
    • Scott Adams
      New here

      By Scott Adams · Posted

      What you've described—the severe weight loss, the cycle of medications making things worse, and the profound fear of eating before leaving the house—is a heavy burden to carry for 15 years. It is absolutely not your fault. While everyone's journey with celiac is different, the struggles with the learning curve, social isolation, and dietary grief are feelings many in the community know all too well. Your question about whether you should just eat what you want and manage the symptoms is a heartbreaking one, born from years of frustration. It's crucial to know that the diarrhea is a sign of ongoing damage to your small intestine from gluten, and simply managing the symptom with Imodium doesn't stop that internal harm or the risk of other complications. The fact that you are still getting sick within an hour of eating, even while trying to be gluten-free, is a huge red flag that something isn't right. This could be due to cross-contamination in your kitchen (e.g., using a shared toaster, colander, or condiment jars), hidden gluten in foods, or the possibility of another concurrent condition like refractory celiac disease. Don't give up!  This article has some detailed information on how to be 100% gluten-free, so it may be helpful (be sure to also read the comments section.):    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.