Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

All 4 Markers Positive.....

GDLions

Recommended Posts

GDLions Rookie
GDLions
Posted

Sorry I am new here and not sure if this has already been posted...

 

I just got a call from my pediatrician and she said my 3 year old son's blood work came back and all the markers were positive for Celiac.  She said the next step is to get a scope and biopsy done to confirm.  She also suggested the whole family get tested for it.  

 

So my questions are....if all the markers are positive is the scope necessary, doesn't that tell us he has it?  Can all the markers be positive and the scope come back negative?  

 

Thanks for any info you all may have!

 

 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


powerofpositivethinking Community Regular
powerofpositivethinking
Posted

welcome  :)

 

are the genetic markers you're referring to HLA DQ tests or antibody tests (TTG, DGP, EMA)?

 

If it is the genetic markers of HLA DQ you're referring to then the next step should be to get a complete celiac blood panel drawn.  a complete panel consists of:

 

Comprehensive Celiac Panel:

DGP iga/igg

ttg iga/igg

EMA

Total iga serum-this is a control test to make sure you make enough iga to validate the other testing

check out page 12 in this report for testing information:

Open Original Shared Link

 

If this panel has been drawn then an endoscopy with at least 6 samples taken from the small intestines would be the next step.

 

feel free to post any of your lab results here for others to comment.

 

gluten should continue to be consumed until ALL testing is complete.

 

 

 

 

 

Sorry I am new here and not sure if this has already been posted...

 

I just got a call from my pediatrician and she said my 3 year old son's blood work came back and all the markers were positive for Celiac.  She said the next step is to get a scope and biopsy done to confirm.  She also suggested the whole family get tested for it.  

 

So my questions are....if all the markers are positive is the scope necessary, doesn't that tell us he has it?  Can all the markers be positive and the scope come back negative?  

 

Thanks for any info you all may have!

GFinDC Veteran
GFinDC
Posted

Well, it would be helpful if you got the lab reports and posted them along with the ranges.

 

IMHO, if the antibodies are positive, there is not likely to be a different cause for that.  Antibodies to gliaden are specific to that protein.  Some of the tests are very specific, like the DGP.  But, most doctors want the endoscopy anyway before they will diagnose celiac disease.  Sometimes a doctor will diagnose based on positive antibodies and symptom resolution on the gluten-free diet. But they aren't all going to do that.

 

Something to consider is the ease of testing now vs later.  Getting an endoscopy now before starting the gluten-free diet is the best choice.  If you were to wait until after he was gluten-free for a year and decide to get testing, he would need to go back to eating gluten again for up to 3 months.  That resumed gluten eating can be very unpleasant and sometimes cause other problems.  Reactions to gluten are sometimes more severe after stopping it for awhile and then eating it again.  It's a lifetime diet and it may be easier to stick with it if there is a complete diagnosis.

GDLions Rookie
GDLions
Posted
  • Author

welcome  :)

 

are the genetic markers you're referring to HLA DQ tests or antibody tests (TTG, DGP, EMA)?

 

If it is the genetic markers of HLA DQ you're referring to then the next step should be to get a complete celiac blood panel drawn.  a complete panel consists of:

 

Comprehensive Celiac Panel:

DGP iga/igg

ttg iga/igg

EMA

Total iga serum-this is a control test to make sure you make enough iga to validate the other testing

check out page 12 in this report for testing information:

Open Original Shared Link

 

If this panel has been drawn then an endoscopy with at least 6 samples taken from the small intestines would be the next step.

 

feel free to post any of your lab results here for others to comment.

 

gluten should continue to be consumed until ALL testing is complete.

 

thanks, i will call the doctors office on monday morning and ask for a copy of the results so i can post them and hopefully understand them better.  just so new to this i have no clue :)

  • 2 weeks later...
GDLions Rookie
GDLions
Posted
  • Author

thanks, i will call the doctors office on monday morning and ask for a copy of the results so i can post them and hopefully understand them better.  just so new to this i have no clue :)

Here are the lab results on both of my boys...

Alex

Deam Iga Index 212.3

Gliadin IgA postive

Glia IgG Index 137.9

Gliadin IgG positive

TTG IgA index greater than 100

TTG IgA AB positive

Robert

Deam Iga Index 115.5

Gliadin IgA postive

Glia IgG Index 60.1

Gliadin IgG positive

TTG IgA index greater than 100

TTG IgA AB positive

 

From some studies I have read if the TTG is over 100 there really is no need to do the biopsy.    What do you think?

powerofpositivethinking Community Regular
powerofpositivethinking
Posted

I'd say those are some pretty conclusive results for being celiac!  I'd say the biopsy is up to you.  good luck!

 

Here are the lab results on both of my boys...

Alex

Deam Iga Index 212.3

Gliadin IgA postive

Glia IgG Index 137.9

Gliadin IgG positive

TTG IgA index greater than 100

TTG IgA AB positive

Robert

Deam Iga Index 115.5

Gliadin IgA postive

Glia IgG Index 60.1

Gliadin IgG positive

TTG IgA index greater than 100

TTG IgA AB positive

 

From some studies I have read if the TTG is over 100 there really is no need to do the biopsy.    What do you think?

nvsmom Community Regular
nvsmom
Posted

Wow, it really is unusual to be positive in all celiac tests for an adult, for kids - Wow.

I personally don't think a biopsy is needed but some docs are very by the book and want a patient to jump through hoops before they will diagnose celiac disease. But as you said, when the tTG tests are very high, it is unlikely to be anything else. The DGP and tTG tests are specific to celiac in what causes the villi damage. The AGA tests are positive for gliadin sensitivity. You have blood tests that show damage and indicate gluten sensitivity, unless you suspect other problems or you need a diagnosis for school accommodations that the doc willingly give if biopsies are done, then i would skip the biopsy.

This report discusses the tests on pages 11-12:

Open Original Shared Link

Hope the kids feel better, and I hope your tests are negative.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,164
    • Most Online (within 30 mins)
      7,748
    VGL
    Newest Member
    VGL
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Who's Online (See full list)

  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • DAR girl
      Celiac and allergic to common subs and adds in prepared foods

      By DAR girl · Posted

      Looking for help sourcing gluten-free products that do not contain potato or corn derived ingredients. I have other autoimmune conditions (Psoriatic Arthritis and Sjogrens) so I’m looking for prepared foods as I have fatigue and cannot devote a lot of time to baking my own treats. 
    • Scott Adams
      Disregarded

      By Scott Adams · Posted

      I am so sorry you're going through this. It's completely understandable to feel frustrated, stressed, and disregarded after such a long and difficult health journey. It's exhausting to constantly advocate for yourself, especially when you're dealing with so many symptoms and positive diagnoses like SIBO, while still feeling unwell. The fact that you have been diligently following the diet without relief is a clear sign that something else is going on, and your doctors should be investigating other causes or complications, not dismissing your very real suffering. 
    • Oldturdle
      Paying for my own Celiac screening at WalkInLab so a positive result doesn’t become part of my medical history

      By Oldturdle · Posted

      It is just so sad that health care in the United States has come to this.  Health insurance should be available to everyone, not just the healthy or the rich.  My heart goes out to you.  I would not hesitate to have the test and pay for it myself.  My big concern would be how you could keep the results truly private.  I am sure that ultimately, you could not.  A.I. is getting more and more pervasive, and all data is available somewhere.  I don't know if you could give a fake name, or pay for your test with cash.  I certainly would not disclose any positive results on a private insurance application.  As I understand it, for an official diagnosis, an MD needs to review your labs and make the call.  If you end up in the ER, or some other situation, just request a gluten free diet, and say it is because you feel better when you don't eat gluten.      Hang in there, though.  Medicare is not that far away for you, and it will remove a lot of stress from your health care concerns.  You will even be able to "come out of the closet" about being Celiac!
    • plumbago
      Paying for my own Celiac screening at WalkInLab so a positive result doesn’t become part of my medical history

      By plumbago · Posted

      Yes, I've posted a few times about two companies: Request a Test and Ulta Labs. Also, pretty much we can all request any test we want (with the possible exception of the N protein Covid test and I'm sure a couple of others) with Lab Corp (or Pixel by Lab Corp) and Quest. I much prefer Lab Corp for their professionalism, ease of service and having it together administratively, at least in DC. And just so you know, Request a Test uses Lab Corp and Quest anyway, while Ulta Labs uses only Quest. Ulta Labs is cheaper than Request a Test, but I am tired of dealing with Quest, so I don't use them so much.
    • Scott Adams
      Does Dailymed.nlm.nih.gov site have filters for gluten?

      By Scott Adams · Posted

      PS - I think you meant this site, but I don't believe it has been updated in years: http://glutenfreedrugs.com/ so it is best to use: You can search this site for prescriptions medications, but will need to know the manufacturer/maker if there is more than one, especially if you use a generic version of the medication: To see the ingredients you will need to click on the correct version of the medication and maker in the results, then scroll down to "Ingredients and Appearance" and click it, and then look at "Inactive Ingredients," as any gluten ingredients would likely appear there, rather than in the Active Ingredients area. https://dailymed.nlm.nih.gov/dailymed/   
×
×
  • Create New...