Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):
  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Treating Celiac With Psychedelic Drugs?


poneelovesyou

Recommended Posts

poneelovesyou Newbie

So, I know what youre thinking, madness! BUT, after reading this paper recently, I started  to think a bit.

 

Open Original Shared Link

 

So recently I realized that gluten was the cause of my lifelong struggle with depression and anxiety. I also have some evidence that I may be a celiac, but I am not willing to do the gluten challenge in order to find out. Regardless of it I am or not, there are 2 things that have erradicated chemical depression and anxiety from my life: Psychedelic drugs and a gluten-free diet. So the paper above is really interesting because it talks about a psychedelic (DOI) that primarily operates through the 5HT2a receptor (as do the classical psychedelic drugs such as LSD, psilocybin, DMT, mescaline etc). So they observed that through this receptor acitivity specifically, anti-inflammatory effects were observed in specific tissues in the body. One of these areas was the small intestine.

 

Still following me? So, in theory, other 5HT2a agonist may also facilitate this same anti inflammatory effect in the small intestine. obviosuly inflammation of the gut is one of the things that plagues celiacs and NCGS people, so I'm wondering if perhaps psychedelics and a gluten-free diet were treating my depression through the same mechanism; reducing inflammation in the small intestine (and perhaps other areas in the gut?)

 

So now I'm wondering, could psychedelic drugs be a potential candidate to reduce the gut inflammation in celiac disease patients? It seems like these cascading inflammatory processis are what takes so long for the body to get under control even after removing gluten from the diet, and continue to do damage to the body. What do you guys think?


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



ravenwoodglass Mentor

The only way something like that would be feasible is if they were able to remove the psychedelic aspect of the drug. I don't think the general population would get much done during the day while they were watching the walls turn colors and their grasp on the reality around them was oozing away. Psychedelic drugs can also be dangerous for people with certain mental health issues. 

mommida Enthusiast

There would have to be many more years of research before I would trust be treated with psychedelic drug treatment.  I have seen LSD proposed as possible treatment for other disorders an health conditions.

 

I hope you are taking extreme precautions, because I do not believe you are under a doctor's care for your experimentations.  I have seen people completely "bake" their brains on drugs to the point they need to be kept in an institution.  Look at Ozzy Osbourne, he can't really speak anymore, but his family is wealthy enough to have servants care for some of the extreme behavior.  Don't forget his wife admits to a few times he has tried to kill her.

 

There has been research in a home, were a gluten free diet improved some mental disorders and most here have experienced a withdrawal period removing gluten from the diet.   

 

You might wan to look further into the "gut - brain connection theories"  or first brain? gut/mind

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - Jmartes71 posted a topic in Coping with Celiac Disease
      0

      Curious question

    2. - Amy Barnett posted a topic in Gluten-Free Foods, Products, Shopping & Medications
      0

      Question

    3. - Jmartes71 posted a topic in Coping with Celiac Disease
      0

      Alarming

    4. - Maggieinsc commented on Scott Adams's article in Winter 2026 Issue
      5

      Celiac Disease and Longevity: Can Treatment and Healing Improve Long-Term Survival?

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,321
    • Most Online (within 30 mins)
      7,748

    Yvonne Thomas
    Newest Member
    Yvonne Thomas
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • Jmartes71
      So I've been dealing with chasing the name celiac because of my body actively dealing with health issues related to celiac though not eating. Diagnosed in 1994 before foods eliminated from diet. After 25 years with former pcp I googled celiac specialist and she wasn't because of what ive been through. I wanted my results to be sent to my pcp but nothing was sent.I have email copies.I did one zoom call with np with team member from celiac specialist in Nov 2025 and she asked me why I wanted to know why I wanted the celiac diagnosis so bad, I sad I don't, its my life and I need revalidaion because its affecting me.KB stated well it shows you are.I asked then why am I going through all this.I was labeled unruly. Its been a celiac circus and medical has caused anxiety and depression no fault to my own other than being born with bad genetics. How is it legal for medical professionals to gaslight patients that are with an ailment coming for help to be downplayed? KB put in my records that she personally spent 120min with me and I think the zoom call was discussing celiac 80 min ONE ZOOM call.SHE is responsible for not explaining to my pcp about celiac disease am I right?
    • Amy Barnett
      What is the best liquid multivitamin for celiac disease?
    • Jmartes71
      I've noticed with my age and menopause my smell for bread gives me severe migraines and I know this.Its alarming that there are all these fabulous bakeries, sandwich places pizza places popping up in confined areas.Just the other day I suffered a migraine after I got done with my mri when a guy with a brown paper bag walk in front of me and I smelled that fresh dough bread with tuna, I got a migraine when we got home.I hate im that sensitive. Its alarming these places are popping up in airports as well.I just saw on the news that the airport ( can't remember which  one)was going to have a fabulous smelling bakery. Not for sensitive celiacs, this can alter their health during their travel which isn't safe. More awareness really NEEDS to be promoted, so much more than just a food consumption!FYI I did write to Stanislaus to let them know my thoughts on the medical field not knowing much about celiac and how it affects one.I also did message my gi the 3 specialist names that was given on previous post on questions on celiac. I pray its not on deaf door.
    • xxnonamexx
      Thanks for the info. I have been taking the ones you recommended but when I saw this I was curious if it was something else to add to the journey Thank  
    • Jane07
      I used to be able to get the Rivera yougut i havent been able to get it lately. I like getting it did say it did say gluten free. I just looking for a good yogurt that gluten free that i can add some fruit and nuts to any suggestion would be helpful  thanks
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.