Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Clarifying the test results

KAG1010

Recommended Posts

KAG1010 Newbie
KAG1010
Posted

Hi Everyone, 

 

i am am brand new to the board.  Here's my background briefly.  I am 40. I have been trying to have a baby since 2010.  I have been pregnant twice and both ended in miscarriage. A new doctor for IVF ordered a recurrent loss workup.  I see my test results but have a few more tests to do before I am following up with the doctor.  My test results that I believe have to do with celiac are as follows:

 

endomysial Iga Antibody is negative

Tissue Transglutaminase Iga is 44.9. Standard range is 0-19. 

 

Reading through some posts here I think I'm understanding that the Iga antibody is used to show whether the tissue transglutaminase Iga is valid, and not a false positive? Is that accurate? 

 

After 6 rounds of IVF, I feel like I'm a googling expert but for some reason this is really confusing to me! 

 

Thank you in advance!

 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


emma6 Enthusiast
emma6
Posted

the test you had which is listed as negative is called EMA

Open Original Shared Link

your thinking of total Iga which checks that you are not deficient in Iga and are able to produce antibodies. people with an Iga deficiency can get false negative results.

since you tested positive for ttg iga that suggests you're not iga deficient and you most likely have celiac disease.

you can still have celiac with a negative EMA. not everyone will test positive for every test its very hit or miss. so even if none of your other tests come back positive for celiac, the positive ttg iga is enough.

looks like you've finally found the cause behind your problems

 

cyclinglady Grand Master
cyclinglady
Posted

Welcome!  You may have found the reasons for your fertility issues!  You only need one positive on the celiac panel to move forward.  Now, keep eating gluten and get a referral to a GI doctor.  The next step is an endoscopy to obtain intestinal biopsies.  

Open Original Shared Link

Why not just try going gluten free without a diagnosis?  I think you will receive better care and may uncover other issues that could affect a healthy pregnancy (e.g. Anemia, thyroid issues, etc.)  beside, celiac disease is genetic.  A firm diagnosis can help others in your family.  

I just met a woman in a 100% gluten free bakery a few months ago.  She told me that she had issues with conceiving and miscarrying.  Six months after being gluten free (strict), and she was pregnant.  Yep, she had the little guy with her!  I hope the best for you!

 

KAG1010 Newbie
KAG1010
Posted
  • Author

Thank you both so much for your responses. I hope this is the answer. Unexplained infertility is really frustrating because you just keep hoping. But with a potential reason, hopefully I can adjust my diet and hopefully get pregnant! 

 

Thank you

Awol cast iron stomach Experienced
Awol cast iron stomach
Posted

Emma 6 gave you great info on your test question.

I just wanted to say I am sorry for your losses . I hope that you are able to get the help and healing needed to move forward to better health and future conception. I look forward to the day you post that things are progressing in a positive way in your desire for a family.  I went through 3 pregnancies with what was likely undiagnosed celiac, I am a grateful mother that got to keep two on earth.

I have hope and best wishes for you.

Good luck.

Washingtonmama Contributor
Washingtonmama
Posted

My daughter was recently diagnosed, and her doctor agreed, Celiac could very well be the cause for her recurrent miscarriages. She is very excited to have found the problem. Looks like you are on the way to success! Whoohoo!

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,198
    • Most Online (within 30 mins)
      7,748
    Mya H
    Newest Member
    Mya H
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • xxnonamexx
      FDA looking for input on Celiac Gluten sensitivity labeling PLEASE READ and submit your suggestions

      By xxnonamexx · Posted

      Please read: https://www.fda.gov/news-events/press-announcements/fda-takes-steps-improve-gluten-ingredient-disclosure-foods?fbclid=IwY2xjawPeXhJleHRuA2FlbQIxMABicmlkETFzaDc3NWRaYzlJOFJ4R0Fic3J0YwZhcHBfaWQQMjIyMDM5MTc4ODIwMDg5MgABHrwuSsw8Be7VNGOrKKWFVbrjmf59SGht05nIALwnjQ0DoGkDDK1doRBDzeeX_aem_GZcRcbhisMTyFUp3YMUU9Q
    • cristiana
      Increased intraepithelial lymphocytes after 10 yrs gluten-free

      By cristiana · Posted

      Hi @Atl222 As @trents points out, there could be many reasons for this biopsy result.  I am interested to know, is your gastroenterologist concerned?  Also, are your blood tests showing steady improvement over the years? I remember when I had my last biopsy, several years after diagnosis, mine came back with with raised lymphocytes but no villous damage, too! In my own case, my consultant wasn't remotely concerned - in fact, he said I might still get this result even if all I ever did was eat nothing but rice and water.   My coeliac blood tests were still steadily improving, albeit slowly, which was reassuring.
    • trents
      Increased intraepithelial lymphocytes after 10 yrs gluten-free

      By trents · Posted

      Welcome to the celiac.com community, @Atl222! Yes, your increased lymphocytes could be in response to oats or it could possibly be cross contamination from gluten that is getting into your diet from some unexpected source but not enough to damage the villi. And I'm certain that increased lymphocytes can be caused by other things besides celiac disease or gluten/oats exposure. See attachment. But you might try eliminating oats to start with and possibly dairy for a few months and then seek another endoscopy/biopsy to see if there was a reduction in lymphocyte counts. 
    • Scott Adams
      Brown Rice Vinegar (organic) from Eden Foods is likely gluten free

      By Scott Adams · Posted

      This is a solid, well-reasoned approach. You’re right that “koji” by itself doesn’t indicate gluten status, and the risk really does come down to which grain is used to culture it. The fact that you directly contacted Eden Foods and received a clear statement that their koji is made from rice only, with no wheat or barley, is meaningful due diligence—especially since Eden has a long-standing reputation for transparency. While the lack of gluten labeling can understandably give pause, manufacturer confirmation like this is often what people rely on for traditionally fermented products. As always, trusting your body after trying it is reasonable, but based on the information you gathered, your conclusion makes sense.
    • Scott Adams
      nothing has changed

      By Scott Adams · Posted

      Seven months can still be early in celiac healing, especially if you were mostly asymptomatic to begin with—symptoms like low iron, vitamin D deficiency, nail changes, and hair issues often take much longer to improve because the gut needs time to recover before absorption normalizes. A tTG-IgA of 69 is not “low” in terms of immune activity, and it can take 12–24 months (sometimes longer) for antibodies and the intestinal lining to fully heal, particularly in teens and young adults. Eating gluten again to “test” things isn’t recommended and won’t give you clear answers—it’s far more likely to cause harm than clarity. Weight not changing is also very common in celiac and doesn’t rule anything out. Please know that your frustration and sadness matter; this adjustment is hard, and feeling stuck can really affect mental health. You deserve support, and if you can, reaching out to a GI dietitian or mental health professional familiar with chronic illness could really help you through this phase. This study indicates that a majority of celiacs don't recover until 5 years after diagnosis and starting a gluten-free diet: Mucosal recovery and mortality in adults with celiac disease after treatment with a gluten-free diet However, it's also possible that what the study really shows is the difficulty in maintaining a 100% gluten-free diet. I suspect that if you looked closely at the diets of those who did not recover within 2 years might be that their diets were not 100% gluten-free. Perhaps they ate out more often, or didn't understand all of the hidden ingredients where gluten can hide. Either way, it shows how difficult recovery from celiac disease can be for most people. According to this study: This article explores other causes of flattened villi:    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.