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- Known1 replied to Known1's topic in Introduce Yourself / Share Stuff18Diagnosed Marsh stage 3C in January 2026
@knitty kitty For me, the flushing lasts about 10 hours and not just 60-90 minutes after consuming the vitamins. I am 10-days into taking this already. My urine is neon colored around the clock and I drink between 1/2 to 3/4 of a gallon of water per day. I'll stick with 2 a day for now, but am honestly quite hesitant to do so. I am curious, where... -
- knitty kitty replied to Known1's topic in Introduce Yourself / Share Stuff18Diagnosed Marsh stage 3C in January 2026
Oh, dear, the niacin flush! I've heard repeatedly that the worse the flush, the more your body needs the niacin. If you stick with it, the flushing will not be as bad in a few days. Another way to correct low Niacin level is to take 100 mg of Niacin (nicotinic acid, the flushing kind) every three hours for several days. I've done this myself, and... -
- knitty kitty replied to HectorConvector's topic in Related Issues & Disorders320
Terrible Neurological Symptoms
@HectorConvector, Step off the gas. I'm in the U. S. That was what I remember my doctor telling me thirty years ago. Things may have changed since then. If I've "misremembered," I apologize. I'm human. Things are different on the other side of the pond. Here we go by mg/dl. The smaller incremental changes are more noticeable using mg/dl.... -
- Known1 replied to Known1's topic in Introduce Yourself / Share Stuff18
Diagnosed Marsh stage 3C in January 2026
@knitty kitty Holy smokes, that Life Extension B-Complex is burning me up. My multi-vitamin already has 25mg of Niacin. The b-complex adds another 100mg on top of that. My face, neck, and ears look like the Cardinal I use for my profile pic. I have been on the b-complex for 10-days now and it seems to get a bit worse with each passing day. I think I... -
- HectorConvector replied to HectorConvector's topic in Related Issues & Disorders320Terrible Neurological Symptoms
Evidence from normoglycaemic studies shows that healthy people peak at ~1 hour, and they then return to baseline in 2–3 hours, not 1. CGM shows normal post-meal rises even in metabolically healthy subjects. Clinical tests use the 2-hour value to judge normal glucose clearance. Therefore the 1-hour-back-to-fasting claim contradicts both physiology and clinical d...
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@knitty kitty For me, the flushing lasts about 10 hours and not just 60-90 minutes after consuming the vitamins. I am 10-days into taking this already. My urine is neon colored around the clock and I drink between 1/2 to 3/4 of a gallon of water per day. I'll stick with 2 a day for now, but am honestly quite hesitant to do so. I am curious, where are you reading "the worse the flush, the more your body needs the niacin"? I have been searching for that, but haven't found that anywhere. -
By knitty kitty · Posted
Oh, dear, the niacin flush! I've heard repeatedly that the worse the flush, the more your body needs the niacin. If you stick with it, the flushing will not be as bad in a few days. Another way to correct low Niacin level is to take 100 mg of Niacin (nicotinic acid, the flushing kind) every three hours for several days. I've done this myself, and found the flushing is very short lived. Stay hydrated. The B's are water soluble, so if not needed, they'll be excreted. Hang tight, you'll be okay! -
By knitty kitty · Posted
@HectorConvector, Step off the gas. I'm in the U. S. That was what I remember my doctor telling me thirty years ago. Things may have changed since then. If I've "misremembered," I apologize. I'm human. Things are different on the other side of the pond. Here we go by mg/dl. The smaller incremental changes are more noticeable using mg/dl. Also, I adopted a Ketogenic diet. Ketogenic diets don't spike blood glucose as much, and therefore return to fasting levels sooner. My own experience is my postprandial blood glucose level returned to fasting levels an hour after the end of a meal on a Ketogenic diet. I was asking if the thiamine you take is thiamine hydrochloride or Benfotiamine or Thiamine TTFD. Thiamine Mononitrate is not well absorbed nor utilized by the body. I learned that amounts larger than 100 mgs of thiamine hydrochloride needs to be taken in thiamine deficiency. 500mgs thiamine hydrochloride is recommended by the World Health Organization for several days and look for health improvement. Thiamine is safe and nontoxic even in higher amounts. When thiamine is taken in high doses, there's a big change in energy availability, especially in the brain, where pain is registered. A twenty percent increase in dietary thiamine results in an eighty percent increase in brain function. Thiamine has analgesic properties. I learned about high dose thiamine from Dr. Derek Lonsdale and Dr. Chandler Marrs through their website hormonesmatter.com. I have taken high dose thiamine to correct my deficiency about fifteen years ago. I could feel myself dying, I was so sick and in pain. I was grasping at straws. No harm, no foul, just to try it and see, right? I tried it and that made all the difference. High dose thiamine made astounding health improvements within a very short period of time for me. I wonder if 500 mg of thiamine hydrochloride would have the same effect on you. -
@knitty kitty Holy smokes, that Life Extension B-Complex is burning me up. My multi-vitamin already has 25mg of Niacin. The b-complex adds another 100mg on top of that. My face, neck, and ears look like the Cardinal I use for my profile pic. I have been on the b-complex for 10-days now and it seems to get a bit worse with each passing day. I think I am going to drop down to taking 1/2 of the serving size. In other words, 1 capsule instead of 2. Hopefully dropping to one does the trick. Have you noticed any side effects from that B-complex? It is WAY over the daily recommended values: Thanks for your time, Known1
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By HectorConvector · Posted
Evidence from normoglycaemic studies shows that healthy people peak at ~1 hour, and they then return to baseline in 2–3 hours, not 1. CGM shows normal post-meal rises even in metabolically healthy subjects. Clinical tests use the 2-hour value to judge normal glucose clearance. Therefore the 1-hour-back-to-fasting claim contradicts both physiology and clinical diagnostic standards.
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