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HELP! Please help me read these lab results :)


Looree

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Looree Newbie

Hello all!

Lab results came in and of course Dr not available until next week. I did some research but so many sites with so much information, and I am feeling overwhelmed. 

Here are the results:

Immunoglobulin A, Qn, Serum    156NORMAL

t-Transglutaminase (tTG) IgA        6HIGH

Endomysial Antibody IgA              Positive

Thank you in advance for any input and guidance!

 

 


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tessa25 Rising Star

A positive on any one blood test should lead to a gastroenterologist doing an endoscopy /biopsies to confirm a celiac diagnosis. You have two positives. You need to keep eating gluten until testing is done.

Looree Newbie
8 minutes ago, tessa25 said:

A positive on any one blood test should lead to a gastroenterologist doing an endoscopy /biopsies to confirm a celiac diagnosis. You have two positives. You need to keep eating gluten until testing is done.

Thanks for looking and responding. Hopefully can get in to see a gastroenterologist soon. Will have to wait for regular dr to come back first. Thanks again! 

GFinDC Veteran
(edited)
13 hours ago, Looree said:

Hello all!

Lab results came in and of course Dr not available until next week. I did some research but so many sites with so much information, and I am feeling overwhelmed. 

Here are the results:

Immunoglobulin A, Qn, Serum    156NORMAL

t-Transglutaminase (tTG) IgA        6HIGH

Endomysial Antibody IgA              Positive

Thank you in advance for any input and guidance!

 

 

Oh, I hate to say it but you are totally hosed!  :)  You have celiac disease!  Or most likely do have it.  The endoscopy to prove gut damage is the final test.

But don't worry.  The fix / treatment for celiac disease is one of the best medicines around.  You eat a healthier gluten-free diet with less processed food than most people eat.  More meats, veggies, nuts, eggs, etc.  Your body will thank you for eating better.  Eating real food instead of junk food is an improvement for most people.

Wait until all the testing for celiac disease is completed before going gluten-free.  The antibodies start to decline when we stop eating gluten and the tests aren't accurate then.

There is a "Newbie 101" thread in the coping With Celiac" forum section.  It has some good basic info.

https://www.celiac.com/forums/topic/91878-newbie-info-101/

Edited by GFinDC
Palvyre Apprentice

That EMA test is extremely specific. It's over 99% accurate for Celiac. Given both your positives it's pretty much a definite.

Looree Newbie

Thanks everyone for responding! I am glad to have an answer, just waiting on an appointment with the GE now. @GFinDC thank for link to newbie site. Will defintely be on there for guidance. 

GFinDC Veteran

You are quite welcome Looree.  There are a couple other antibody tests they can do.  They are DGP IgG and DGP IgA.  It's good to have all the tests done.  But a positive on any single antibody is enough to have celiac damage occur.  These tests are usually included in the full celiac test panel.


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    • Samanthaeileen1
      thank you RMJ! That is very helpful advice. Good to know we aren’t crazy if we don’t do the endoscopy. We are going to try the gluten free and see how symptoms and levels improve.    thank you Wheatwacked (love the username lol) that is also reassuring. Thankfully she has an amazing and experienced pediatrician. And yesss I forgot to mention the poop! She has the weirdest poop issues.    How long did it take y'all to start seeing improvement in symptoms? 
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      So her tissue transglutaminase antibody is almost 4x the upper end of the normal range - likely a real result. The other things you can do besides an endoscopy would be: 1.  Genetic testing.  Unfortunately a large proportion of the population has genes permissive for celiac disease, but only a small proportion of those with the genes have it. With family history it is likely she has the genes. 2.  Try a gluten free diet and see if the symptoms go away AND the antibody levels return to normal. (This is what I would do). Endoscopies aren’t always accurate in patients as young as your daughter. Unfortunately, without an endoscopy, some doctor later in her life may question whether she really has celiac disease or not, and you’ll need to be a fierce mama bear to defend the diagnosis! Be sure you have a good written record of her current pediatrician’s diagnosis. Doing a gluten challenge for an endoscopy later in life could cause a very uncomfortable level of symptoms.   Having yourself, your husband and your son tested would be a great idea.  
    • Samanthaeileen1
      here are the lab ranges.  Normal ranges for tissue transglutaminase are: <15.0 Antibody not detected > or = 15.0 Antibody detected normal for endomysial antibody is < 1.5. So she is barely positive but still positive. 
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