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Celiac.com Article:Leaky Gut Could Be a Real Problem for Space Travelers


Jefferson Adams

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    • Theresa2407
      You are correct.  Same place.  I have used their site for so long and have it bookmarked.  Still living in past.  Our support group was affiliated with them.
    • Known1
      Hmm, I think you mean the Gluten Intolerance Group®?  Their website is not gig.net.  Maybe it was at one point?  I am new to all of this, but did find their website here:  https://gluten.org/ Kind Regards, Known1
    • knitty kitty
      @Scott Adams, You're right about corn and wheat not sharing similarities in the 33-mer peptide segment of gluten.  Corn has a completely different peptide that causes an autoimmune reaction because it attaches to HLA-DQ8.  Casein in dairy shares with wheat similarities in the33-mer peptide chain. Sorry about the oversimplification.  Maize Prolamins Could Induce a Gluten-Like Cellular Immune Response in Some Celiac Disease Patients https://pmc.ncbi.nlm.nih.gov/articles/PMC3820067/
    • Scott Adams
      I just want to mention that corn and wheat do both contain storage proteins (corn has zein, wheat has gliadin and other gluten proteins), and there are some small similarities in certain amino acid sequences. However, those similarities are not considered medically equivalent, and corn proteins do not trigger the autoimmune response of celiac disease in the vast majority of people with celiac. Celiac disease specifically involves an immune reaction to gluten peptides found in wheat, barley, and rye. Corn is classified as gluten-free because its proteins do not activate that same immune pathway in most individuals. Although corn intolerance is very real, the explanation about the proteins being the same is oversimplified to the point where it's not accurate.
    • knitty kitty
      @Heatherisle, Newly diagnosed people often suffer from nutritional deficiencies.  Thiamine B1 stores can be depleted within a few weeks.  Thiamine deficiency can be localized in the gastrointestinal tract causing Gastrointestinal Beriberi.  It is under diagnosed by doctors!  Dysfunction of the gallbladder can be seen in Gastrointestinal Beriberi.   Have your daughter mention the possibility of Gastrointestinal Beriberi to her dietician!  Gastrointestinal Beriberi will be improved with high dose Thiamine administration, orally or by IV.  It's important to have thiamine deficiency corrected as quickly as possible to prevent life threatening health problems and risk permanent damage.   I had Gastrointestinal Beriberi but my doctors did not recognize it.  I had diarrhea.  I had my gallbladder removed (gallbladder attack).  Still had diarrhea.  My thiamine deficiency progressed to Wernickes Encephalopathy.  My doctors diagnosed me as "depressed".   I corrected the thiamine deficiency at home with over the counter Thiamine Hydrochloride tablets.  I'm very thankful I studied Nutrition.   See if the symptoms match:  Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/ Gastrointestinal Beriberi Presenting With Chronic Diarrhea: A Case Report https://pmc.ncbi.nlm.nih.gov/articles/PMC12794365/
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