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GPA IgG results


Lotte18

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Lotte18 Contributor

Hi all,

I was diagnosed last January and my TTG level is down to 4.  The range is 1-3.   My IgA test is within the normal range.  I don't know what IgA is.

My Glaiadin peptide AB IgG is way high, 86.  The top of the range is 19.  I'm waiting to hear back from my doctor but in the meantime, can someone tell me what IgG is?  Is this a food allergy number?  

Many thanks, Charlotte


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Scott Adams Grand Master

Welcome to the forum! The article below is older, but still explains the tests well. It looks like you have two positive blood tests for celiac disease, so it is likely that will be your diagnosis. Your doctor may want to do an endoscopy and biopsy to confirm this, and to do that you should still be eating gluten daily for ~2 weeks before the biopsy.

 

Lotte18 Contributor

Hi Scott, Thanks for getting back to me.  And thanks for sending the article.  Not sure I understand my results any better though.

I was diagnosed over a year ago with testing and an endoscopy.  I know I'm celiac.  This was the 5th follow up test to see if my gluten levels were dropping.  My TTG was down from the initial 27, to 5 last fall but I still had pain on the left side of my body.  My Primary care just thought I was still healing.  In Feb. I took a home test from Imaware and got higher numbers.  The TTG was 7.1 with a cutoff of 5.4U.  The IGG was 155.6U--the cutoff being 10.5U.  So that was worrisome.  So I saw a celiac specialist.  She ordered another round of testing.  That came up with the TTG at 4, cutoff at 3; IGG at 86, cutoff at--I think it was 19.  So two separate tests (although interpretive as they may be, are giving similarly high results for IGG).  And I still experience intestinal swelling and pain over my left hip.  I've no idea where the gluten is coming from, or if that's the problem. The specialist has mentioned it might be bad bacteria at this point.  I still have to test for that.  Not looking forward to doing the Quintron breath test since it requires a 24 hour prep.  Urg!  

Scott Adams Grand Master

Thank you for the clarification, and you did mention in your initial post that you were already diagnosed, so my bad for not catching that.

There have been some studies that show that cow's milk can increase tTG levels in some people, so you may want to try eliminating dairy for a while to see if that helps to bring down your levels to normal, however, many people report it taking a year or more before those levels get back to normal.

Also, if you eat gluten-free oats you may want to exclude them as well, as ~9% of celiacs also have a reaction to them, which seems to be a separate intolerance.

Lotte18 Contributor

Thanks Scott,

I eliminated all dairy, oats, and soy right after my diagnosis.  Funny enough I've just added dairy back in, (after the tests were taken however).  I really need the calcium.  So I'm drinking A2 milk which is delicious and doesn't seem to make anything any worse.  The specialist thought my diet may have been too restrictive.  I can't win.  I just feel exhausted.  Sorry to make you slog through all the details.  

Thanks for being there, Charlotte

Scott Adams Grand Master

No worries, and it could just take more time for you to heal. Hopefully you are taking vitamin & mineral supplements, many celiacs are deficient in many different nutrients, and this can also help with recovery. @Wheatwacked has posted here extensively on this topic, and this particular post may be helpful:

 

knitty kitty Grand Master
On 3/24/2022 at 3:14 PM, Lotte18 said:

Thanks Scott,

I eliminated all dairy, oats, and soy right after my diagnosis.  Funny enough I've just added dairy back in, (after the tests were taken however).  I really need the calcium.  So I'm drinking A2 milk which is delicious and doesn't seem to make anything any worse.  The specialist thought my diet may have been too restrictive.  I can't win.  I just feel exhausted.  Sorry to make you slog through all the details.  

Thanks for being there, Charlotte

Hello!

What are you including in your diet?  Are you taking any medications that might contain gluten as a filler? 

Do you eat processed gluten free facsimile foods? 

Have you been checked for vitamin and mineral deficiencies?

Have you tried the Autoimmune Protocol diet?

 

 


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Lotte18 Contributor

Hi,  I don't take medications that have gluten.  My toothpaste etc. is gluten free.  I've had blood tested for deficiencies.  The only thing I can think of might be sliced cantaloupe from Whole Foods.  So I've stopped eating that.  Maybe their cutting boards have gluten?  

I don't know what the AP diet is.  

Many thanks

knitty kitty Grand Master
(edited)

The AutoImmune Protocol Diet was developed by a doctor with Celiac Disease for herself and her Celiac children and others who have autoimmune diseases.

The AIP diet has been scientifically proven to promote healing in the body.

https://www.thepaleomom.com/start-here/the-autoimmune-protocol/

This diet has really helped me recover.  I was astounded at how quickly these dietary changes helped me feel better.  

I hope you look into it.  

Also IgG Dpg is another test for Celiac immune response used often in children and young adults.  The note worthy point is that your levels are going down over the past year.  It can take eighteen months to two years to heal from Celiac damage.  

By following the Autoimmune Protocol diet, a Paleo diet, you can further reduce inflammation and speed healing.  

 

Edited by knitty kitty
Add link and information
Lotte18 Contributor

Hi Knitty kitty!

Thanks so much for your help.  I will look into it!

Best, Charlotte

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    • knitty kitty
      I followed the Autoimmune Protocol Diet which is really strict for a while, but later other foods can be added back into your diet.  Following the AIP diet strictly allows you digestive system to heal and the inflammation to calm down.  Sort of like feeding a sick baby easy to digest food instead of spicy pizza.   It's important to get the inflammation down because chronic inflammation leads to other health problems.  Histamine is released as part of the autoimmune response to gluten.  High histamine levels make you feel bad and can cause breathing problems (worsening asthma), cardiovascular problems (tachycardia), and other autoimmune diseases (Hashimoto's thyroiditis, diabetes) and even mental health problems. Following the low histamine version of the AIP diet allows the body to clear the histamine from our bodies.  Some foods are high in histamine.  Avoiding these makes it easier for our bodies to clear the histamine released after a gluten exposure.   Vitamin D helps regulate the immune system and calm it down.  Vitamin D is frequently low in Celiacs.  The B Complex vitamins and Vitamin C are needed to clear histamine.   Supplementing with essential vitamins and minerals boosts your intestines' ability to absorb them while healing.   Keep in mind that gluten-free facsimile foods, like gluten-free bread, are not enriched with added vitamins like their gluten containing counterparts are.   They are empty calories, no nutritional value, which use up your B vitamins in order to turn the calories into fuel for the body to function.   Talk to your doctor or nutritionist about supplementing while healing.  Take a good B Complex and extra Thiamine in the form Benfotiamine (shown to promote gut health).  Most B Complex vitamins contain thiamine mononitrate which the body cannot utilize.  Meats and liver are good sources of B vitamins.   Dr. Sarah Ballantyne wrote the book, the Paleo Approach.  She's a Celiac herself.  Her book explains a lot.   I'm so glad you're feeling better and finding your balance!
    • klmgarland
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    • knitty kitty
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      Thank you, a little expensive but glad to have this source. 
    • Xravith
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