Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):
  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Pernicious Anemia


Mtndog

Recommended Posts

Mtndog Collaborator

I was recently told I am anemic and I'm wondering if it's pernicious anemia. I know that for the last month (after a really harsh glutening) I have been having some of the symptoms I had before I went gluten-free like the tarry stools, nausea, muscle pain and spasms, numbness and tingling and I'm wondering if if may be this.

And if so, how is it traeted? b12 shots? Anemia confuses me because i always thought it was low iron so anyone willing to educate me, please explain! Thanks, B


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



ravenwoodglass Mentor

What kind of anemia did the doctor say you have? There are many different forms. I am assuming it was diagnosed through blood work?

True pernicious anemia is caused by the body not producing something called the intrinsic factor. The intrinsic factor is what allows the body to absorb and utilize B12 from our guts. Many celiacs because of the damage done to the intestines are also unable to absorb the vitamin from food or supplements and are low in B12. It is not exactly the same thing but the effects are the same.

For many the use of sublingual B12 is enough to get relief. The sublingual tabs dissolve under the tongue and are absorbed by the mucous membranes into the blood stream. This can be a very effective way of bringing levels up quickly. Some folks choose to get injections, my Mom did for years, but for some the oral method works well. I had relief, even pregluten free, from 'tingles' in under a week with the sub tabs

Mtndog Collaborator
What kind of anemia did the doctor say you have? There are many different forms. I am assuming it was diagnosed through blood work?

True pernicious anemia is caused by the body not producing something called the intrinsic factor. The intrinsic factor is what allows the body to absorb and utilize B12 from our guts. Many celiacs because of the damage done to the intestines are also unable to absorb the vitamin from food or supplements and are low in B12. It is not exactly the same thing but the effects are the same.

For many the use of sublingual B12 is enough to get relief. The sublingual tabs dissolve under the tongue and are absorbed by the mucous membranes into the blood stream. This can be a very effective way of bringing levels up quickly. Some folks choose to get injections, my Mom did for years, but for some the oral method works well. I had relief, even pregluten free, from 'tingles' in under a week with the sub tabs

They actually didn't say what kind of anemia- I didn't realize there were different types. thanks for the info. I was looking over my labs and it looks like B12 and iron.

tiffjake Enthusiast
They actually didn't say what kind of anemia- I didn't realize there were different types. thanks for the info. I was looking over my labs and it looks like B12 and iron.

You might want to find out if it is pernicious anemia or not. If so, you will need B12 for life. I have pernicious anemia. I used to give myself weekly shots. I stopped doing that b/c I developed bad bruises and scar tissue. I started using the sublingual tab (from GNC).

If you do not have pernicious anemia, then you can use over the counter Iron or B12 tablets. (They would not have to be sublingual). The only reason people with pernicious anemia need the shots or sublingual is because they can not absorb the B12 through the stomach lining. Otherwise, regular Iron pills or B12 pills would be fine.

Hope you figure out what kind of anemia you have! :)

chatycady Explorer

I too have pernicious anemia. And will give my self monthly injections for the rest of my life. I was diagnosed through the "Shillings" test. Don't know if they use that anymore.

You can be anemic, due to poor absorption. I do not have that problem. I lack intrensic factor. Pernicious Anemia is an autoimmune disease.

Mtndog Collaborator

Thanks for all the info everyone!

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - Jane02 replied to HectorConvector's topic in Related Issues & Disorders
      314

      Terrible Neurological Symptoms

    2. - Jane02 replied to HectorConvector's topic in Related Issues & Disorders
      314

      Terrible Neurological Symptoms

    3. - knitty kitty replied to HectorConvector's topic in Related Issues & Disorders
      314

      Terrible Neurological Symptoms

    4. - trents commented on Amiah's blog entry in Amiah
      1

      Help!!

    5. - Scott Adams replied to HectorConvector's topic in Related Issues & Disorders
      314

      Terrible Neurological Symptoms

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,581
    • Most Online (within 30 mins)
      7,748

    MaggieSc
    Newest Member
    MaggieSc
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Who's Online (See full list)

  • Upcoming Events

  • Posts

    • Jane02
      Sorry, I just realized how old this thread is and only read the initial post from 2021. I'll have to catch up on the comments in this thread. 
    • Jane02
      Sorry to hear you're going through such a hard time. It would be worth looking into MCAS/histamine issues and also Long Covid. Perhaps there is something occurring in addition to celiac disease. It would be worth ruling out micronutrient deficiencies such as the b vitamins (B12, folate, B1, etc), vit D, and ferritin (iron stores). 
    • knitty kitty
      This sounds very similar to the neuropathic pain I experienced with type two diabetes.  Gloves and boots pattern of neuropathy is common with deficiencies in Cobalamine B12 (especially the pain in the big toe), Niacin B3, and Pyridoxine B6.  These are vitamins frequently found to be low in people with pre-diabetes and diabetes.  Remember that blood tests for vitamin levels is terribly inaccurate.  You can have vitamin deficiencies before there are any changes in blood levels.  You can have "normal" serum levels, but be deficient inside organs and tissues where the vitamins are actually utilized.  The blood is a transportation system, moving vitamins absorbed in the intestines to organs and tissues.  Just because there's trucks on the highway doesn't mean that the warehouses are full.  The body will drain organs and tissues of their stored vitamins and send them via the bloodstream to important organs like the brain and heart.  Meanwhile, the organs and tissues are depleted and function less well.   Eating a diet high in simple carbohydrates can spike blood sugar after meals.  Eating a diet high in carbohydrates consistently over time can cause worsening of symptoms.  Thiamine and other B vitamins like Niacin B3 and Pyridoxine B6, (which I noticed you are not supplementing), are needed to turn carbs, proteins and fats into energy for the body to use.  Alcohol consumption can lower blood sugar levels, and hence, alleviate the neuropathic pain.  Alcohol destroys many B vitamins, especially Pyridoxine, Thiamine and Niacin.  With alcohol consumption, blood glucose is turned into fat, stored in the liver or abdomen, then burned for fuel, thus lowering blood glucose levels.  With the cessation of alcohol and continued high carb diet, the blood glucose levels rise again over time, resulting in worsening neuropathy.   Heavy exercise can also further delete B vitamins.  Thiamine and Niacin work in balance with each other.  Sort of like a teeter-totter, thiamine is used to produce energy and Niacin is then used to reset the cycle for thiamine one used again to produce energy.  If there's no Niacin, then the energy production cycle can't reset.  Niacin is important in regulating electrolytes for nerve impulse conduction.  Electrolyte imbalance can cause neuropathic pain.   Talk to your doctors about testing for Type Two diabetes or pre-diabetes beyond an A1C test since alcohol consumption can lower A1C giving inaccurate results. Talk to your doctors about supplementing with ALL eight B vitamins, and correcting deficiencies in Pyridoxine, Niacin, and B12.  Hope this helps! Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet https://pubmed.ncbi.nlm.nih.gov/19154566/ P. S.  Get checked for Vitamin C deficiency, aka Scurvy.  People with Diabetes and those who consume alcohol are often low in Vitamin C which can contribute to peripheral neuropathy.
    • Scott Adams
      I’m really sorry you’re dealing with this—chronic neuropathic or nociplastic pain can be incredibly frustrating, especially when testing shows no nerve damage. It’s important to clarify for readers that this type of central sensitization pain is not the same thing as ongoing gluten exposure, particularly when labs, biopsy, and nutritional status are normal. A stocking/glove pattern with normal nerve density points toward a pain-processing disorder rather than active celiac-related injury. Alcohol temporarily dampening symptoms likely reflects its central nervous system depressant effects, not treatment of an underlying gluten issue—and high-dose alcohol is dangerous and not a safe or sustainable strategy. Seeing a pain specialist is absolutely the right next step, and we encourage members to work closely with neurology and pain management rather than assuming hidden gluten exposure when objective testing does not support it.
    • Scott Adams
      There is no credible scientific evidence that standard water filters contain gluten or pose a gluten exposure risk. Gluten is a food protein from wheat, barley, or rye—it is not used in activated carbon filtration in any meaningful way, and refrigerator or pitcher filters are not designed with food-based binders that would leach gluten into water. AI-generated search summaries are not authoritative sources, and they often speculate without documentation. Major manufacturers design filters for water purification, not food processing, and gluten contamination from a water filter would be extraordinarily unlikely. For people with celiac disease, properly functioning municipal, bottled, filtered, or distilled water is considered gluten-free.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.