Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Results In....

Disney323

Recommended Posts

Disney323 Apprentice
Disney323
Posted

...dr. says our 17 month old son doesn't have celiac. He had a biopsy 10 days ago. He feels this could be a milk allergy. Our son was on hypoallergenic formula from 4weeks until 1 yr. becuase he had reactions to the milk. He ran more blood tests today for other foods because he feels this is a food allregy. Our son has damage in his small bowel and his esophogus. We have to have him dairy free for 2 weeks, if no improvement then on prilosec. Any thoughts about this? Could it still be celiac? (he tested high on one of the blood tests, but not the serum or ttga)

Andrea

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


confused Community Regular
confused
Posted
...dr. says our 17 month old son doesn't have celiac. He had a biopsy 10 days ago. He feels this could be a milk allergy. Our son was on hypoallergenic formula from 4weeks until 1 yr. becuase he had reactions to the milk. He ran more blood tests today for other foods because he feels this is a food allregy. Our son has damage in his small bowel and his esophogus. We have to have him dairy free for 2 weeks, if no improvement then on prilosec. Any thoughts about this? Could it still be celiac? (he tested high on one of the blood tests, but not the serum or ttga)

Andrea

Which blood test was high, was it the IgG?

And what new blood test did he run for food allergies?

paula

Disney323 Apprentice
Disney323
Posted
  • Author

Hi Paula,

I believe it was the Igg or the IGA. Honestly, I've had so many things thrown at me I don't know which end is up. He is running tests for milk, whey, wheat, fruits. and a lot more that I just don't know of. IGE too which I believe is for milk. Thanks for writing.

shayesmom Rookie
shayesmom
Posted
...dr. says our 17 month old son doesn't have celiac. He had a biopsy 10 days ago. He feels this could be a milk allergy. Our son was on hypoallergenic formula from 4weeks until 1 yr. becuase he had reactions to the milk. He ran more blood tests today for other foods because he feels this is a food allregy. Our son has damage in his small bowel and his esophogus. We have to have him dairy free for 2 weeks, if no improvement then on prilosec. Any thoughts about this? Could it still be celiac? (he tested high on one of the blood tests, but not the serum or ttga)

Andrea

The biopsy can only rule Celiac IN, it can never rule it OUT.

No matter what the results are, I would also follow up with an elimination diet in conjunction with keeping a food journal. It truly is the most accurate way of figuring out food issues.

Also, there are plenty of people out there who are gluten-sensitive and yet will never test positive for Celiac Disease....they just don't have the genes predisposing them to celiac disease. And yet, if you remove gluten from diet, they improve dramatically. This is one of those grey areas where you may have to follow through with your own methods of "testing" and rely on what you are actually observing. It's not an ideal situation (as compared with official doctor diagnosis), but it will give you accurate results.

Of course, this is all up to you to decide on how to proceed. Personally, I'd be worried about a prescription for Prilosec considering it can block calcium absorption and has been linked to osteoporosis in older people. There isn't any information on how it affects bones in young children. If it were me, I'd follow up with further allergy tests and dietary trial before committing to medication. Perhaps you can talk to your doc about following through with an elimination diet and having him also observe any changes.

With small bowel damage, the culprits are usually gluten, dairy, soy and/or corn. That's not to say that other food allergies couldn't be present....just that these foods are most commonly linked to small bowel damage.

2boysmama Apprentice
2boysmama
Posted
Also, there are plenty of people out there who are gluten-sensitive and yet will never test positive for Celiac Disease....they just don't have the genes predisposing them to celiac disease. And yet, if you remove gluten from diet, they improve dramatically.

This is us to a "T" (in fact Vicky was the one who helped me finally figure that out! LOL). Removing gluten from our diets has improved our health in SO many ways - and yet we don't carry the genes for celiac disease - "only" for gluten sensitivity.

pwalasik Newbie
pwalasik
Posted
This is us to a "T" (in fact Vicky was the one who helped me finally figure that out! LOL). Removing gluten from our diets has improved our health in SO many ways - and yet we don't carry the genes for celiac disease - "only" for gluten sensitivity.

What are the genes that indicate gluten sensitivity versus the genes that indicate possible predisposition for Celiac Disease? Thank you for any information regarding genes/ HLA typing.

shayesmom Rookie
shayesmom
Posted
What are the genes that indicate gluten sensitivity versus the genes that indicate possible predisposition for Celiac Disease? Thank you for any information regarding genes/ HLA typing.

Celiac Disease genes (as recognized in U.S.)

HLA-DQ2

HLA-DQ8

(Celiac genes recognized in other countries but not in U.S.)

HLA-DQ9

HLA-DR3

HLA-B8

HLA-DQ7

Gluten sensitivity genes

HLA-DQ1

HLA-DQ3

HLA-DQ5

HLA-DQ6

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Christine E Newbie
Christine E
Posted

From what I've read, children under three generally do not have positive blood tests because their immune systems are not fully developed until around age three. My son has gene DQ2, and the diet was successful at 13 months, but he has never had a positive blood test. His endoscopy showed "changes" in the cilia.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. JoJo0611
      - JoJo0611 posted a topic in Gluten-Free Foods, Products, Shopping & Medications
      0

      Yeast extract

      Please can anyone help. I was diagnosed on 23rd December and I am trying my best to get my head around all the things to look out for. I have read that yeast extract is not to be eaten by coeliacs. Why? And is this all yeast extract. Or is this information wrong. Thanks.
    2. trents
      - trents replied to Seabeemee's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      1

      Labs ? Awaiting in person follow up with my GI

      Welcome to the celiac.com community, @Seabeemee! The fact that the genetic testing shows you do not have either of the two genes associated with the potential to develop celiac disease (HlA DQ2 and HLA DQ8) pretty much ensures that you do not have celiac disease and the biopsy of the small bowel showing "normal villous architecture" confirms this. But...
    3. Seabeemee
      - Seabeemee posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      1

      Labs ? Awaiting in person follow up with my GI

      My Doctor messaged me that I have no sign of Celiac disease so until I meet with her next week I don’t know what the labs mean. I am being evaluated by my new GI for Celiac disease because of digestive issues (bloating, distention, fullness in mid section, diarrhea). I also have been diagnosed with GERD and some associated issues hence the endoscopy. ...
    4. Scott Adams
      - Scott Adams commented on Scott Adams's article in Diagnosis, Testing & Treatment
      7

      A Future Beyond the Gluten-Free Diet? Scientists Test a New Cell Therapy for Celiac Disease (+Video)

      The link at the bottom of the article is the source: https://www.science.org/doi/10.1126/scitranslmed.adr8941
    5. trents
      - trents replied to mike101020's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      EMA Result

      Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for.
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,165
    • Most Online (within 30 mins)
      7,748
    AmynDevyn
    Newest Member
    AmynDevyn
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • JoJo0611
      Yeast extract

      By JoJo0611 · Posted

      Please can anyone help. I was diagnosed on 23rd December and I am trying my best to get my head around all the things to look out for. I have read that yeast extract is not to be eaten by coeliacs. Why? And is this all yeast extract. Or is this information wrong. Thanks. 
    • trents
      Labs ? Awaiting in person follow up with my GI

      By trents · Posted

      Welcome to the celiac.com community, @Seabeemee! The fact that the genetic testing shows you do not have either of the two genes associated with the potential to develop celiac disease (HlA DQ2 and HLA DQ8) pretty much ensures that you do not have celiac disease and the biopsy of the small bowel showing "normal villous architecture" confirms this. But you could have NCGS (Non Celiac Gluten Sensitivity) which would not damage the villous architecture. You could also have SIBO (Small Intestine Bacterial Overgrowth) or H. Pylori infection. Both of these conditions would thrive on carbs and you do say you feel better when you don't eat a lot of carbs. And with your resection of the small bowel, that could be causing it's own problems like you describe. When was that surgery done? You have had over 1 foot of your small bowel removed by that surgery in 2022 so that would certainly challenge digestion and nutrient absorption.  Edited
    • Seabeemee
      Labs ? Awaiting in person follow up with my GI

      By Seabeemee · Posted

      My Doctor messaged me that I have no sign of Celiac disease so until I meet with her next week I don’t know what the labs mean. I am being evaluated by my new GI for Celiac disease because of digestive issues (bloating, distention, fullness in mid section, diarrhea).  I also have been diagnosed with GERD and some associated issues hence the endoscopy. I also was diagnosed with NAFLD after an abdominal CT scan in December - which surprises me because I gave up alcohol 5 years ago, workout 5 days a week, cardio / weights and cook from scratch every night. Anecdotally,  I do feel better when I do not eat a lot of carbs and have been staying away from gluten 95% of the time until my follow up.  History: I had an emergency bowel obstruction operation in August 2021 for a double closed loop obstruction, open surgery removed 40 cm of my small intestine, my appendix, cecal valve and illeocectomy. Beside the fact that this put me in the situation of no longer being able to absorb Vitamin B12  from my diet and having to  inject Vit B 12 2x a month, I also became Iron deficient and am on EOD iron to keep my levels high enough to support my Vitamin B12 injections, as well as daily folic acid. I tested positive for pernicious anemia in 2022 but most recently that same test came back negative. Negative Intrinsic Factor. My results from the biopsies showed 2nd part of Duodenum, small bowel Mildly patch increased intraepithelial lymphocytes with intact villious architecture. Comment: Duodenal biopsies with normal villous architecture and increased intrepithelial lymphocytes (Marsh I lesion) are found in 1-3% of patients undergoing duodenal biopsy, and an association with celiac disease is well established however the specificity remains low. Similar histologic findings may be seen in H pylori gastritis, NSAID and other medication use including olmesartan, bacterial overgrowth, tropical sprue and certain autoimmune disorders. So my GI ordered Labs for Celiac confirmation: Sorry I couldn’t upload a photo or pdf so typed below: TEST NAME                               IN RANGE and/or RESULTS RESULTS:  IMMUNOGLOBULIN A :           110 GLIADIN (DEAMIDATED) AB (IGG, IGA)                            <1.0 GLIADIN (DEAMIDATED) AB (IGA)                                     <1.0 GLIADIN (DEAMIDATED) AB (IGG)                                    <1.0 TISSUE TRANSGLUTAMINASE ANTIBODY, IGG, IGA TISSUE TRANSGLUTAMINASE AB, IGG                                     <1.0 TISSUE TRANSGLUTAMINASE AB, IGA                                     <1.0 INTERPRETATION: <15.0 ANTIBODY NOT DETECTED  > OR = 15.0 ANTIBODY DETECTED RESULTS: HLA TYPING FOR CELIAC DISEASE INTERPRETATION (note The patient does not have the HLA-DQ associated with celiac disease variants) More than 97% of celiac patients carry either HLA-DQ2 (DQA1*05/DQB1*02) or HLA-DQ8 (DQA1*03/DQB1*0302) or both. Genetic counseling as needed. HLA DQ2 : NEGATIVE HLA D08: NEGATIVE HLA VARIANTS DETECTED: HLA DA1* : 01 HLA DA1* : 05 HLA DQB1*: 0301 HLA DQB1*: 0501 RESULTS REVIEWED BY: Benjamin A Hilton, Ph.D., FACMG I appreciate any input, thank you.         
    • trents
      EMA Result

      By trents · Posted

      Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for.
    • Scott Adams
      Violent reaction to gluten after going gluten-free?

      By Scott Adams · Posted

      This article, and the comments below it, may be helpful:    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.