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Enzyme Treatment

cgilsing

By cgilsing
in Coping with Celiac Disease

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cgilsing Enthusiast
cgilsing
Posted

I'm sure there are probably plenty of posts on the topic already....but I haven't been around in a while and I'm having a hard time locating any previous discussions. :rolleyes: Does anybody know what is happening with the research being done in regards to the new enzyme that is supposed to break down gluten and make it safe to eat??? Are they doing trials yet? What are your thoughts on the subject??

just to be clear I'm refering to the AN-PEP enzyme that was published last June as being a very promising treatment for celiac disease..... ;)

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Nic Collaborator
Nic
Posted

I don't know anything about that enzyme but I do know that Alba Therapuetics (sp?) are in stage 2 of their trial which means they are now testing on people. They made a drug/enzyme? called AT-1001.

happygirl Collaborator
happygirl
Posted

cgilsing,

If I'm not mistaken, is that the enzyme from Stanford? Hopefully someone can chime in more.

Dr. Fasano's drug, AT-1001 has been in human tests since fall 2005 (at least). It stops the overproduction of zonulin, which keeps the "gates" closed, so that gluten doesn't pass through the barrier cells, and hence, stops the autoimmune reaction from having the chance to occur.

Laura

cgilsing Enthusiast
cgilsing
Posted
  • Author

I'm not sure if it is the same as AT-1001, but it says that this research was done in the Netherlands....

Here is a link to the article:

Open Original Shared Link

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