Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Help Interpreting Blood Test!

MM5079

Recommended Posts

MM5079 Rookie
MM5079
Posted

Hi, All!

I've read and read the site about the blood test, but I'm still a little confused. The nurse called me on the phone to tell me the results, but said everything so fast I couldn't process it well. He said that my anti-tissue transglutaminase (tTG-IgA) was 24 and the typical high is 19. He then said my endomysial was below the high raito of 1-10 or something to that effect! Either way, he said that my results do suggest Celiacs, and they will be doing a biopsy next week! Can anybody tell me if this test alone is indicitive of Celiacs? What's the percentage of a confirmed diagnosis of Celiacs of individuals with an anti-tissue transglutaminase (tTG-IgA) of 24?

I have an uncle with Celiacs, and finally gave in to his pressure for getting tested. I have been going though hell with GI issues. I hope this is finally an answer and my peripheral neuropathy will go away!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


ravenwoodglass Mentor
ravenwoodglass
Posted

You finally have your answer. When the tests are positive it is pretty certain that you are celiac. Even if the biopsy turns out to be a 'negative' you really should get on the diet. False negatives on both blood and biopsy are all too common.

MM5079 Rookie
MM5079
Posted
  • Author
You finally have your answer. When the tests are positive it is pretty certain that you are celiac. Even if the biopsy turns out to be a 'negative' you really should get on the diet. False negatives on both blood and biopsy are all too common.

It's almost too good to be true to finally know what's wrong with me. Should I continue eating Gluten until after the biopsy on the 23rd, or is it safe to go ahead and limit my intake as I've been doing?

psawyer Proficient
psawyer
Posted

If you are going to have a biopsy in the near future, I would recommend that you not change your diet until after the procedure. Next week is just days away. A high tTG-IgA is indicative of celiac disease, but a positive biopsy will confirm that celiac is indeed the cause.

My opinion, for what it is worth, is that once the endoscopy is done, I would adopt a gluten-free diet based on the tTG-IgA test alone.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,699
    • Most Online (within 30 mins)
      7,748
    RelievedP
    Newest Member
    RelievedP
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Bennyboy1998
      Potential celiac need advice

      By Bennyboy1998 · Posted

      Yes gene HLADQ2 was positive 
    • Wends
      Inconclusive results

      By Wends · Posted

      Wow, the system is crazy isn’t it? Maybe switch Doctors if you can. It’s surprising from what you’ve written it seems obvious it’s celiac disease. The “potential” diagnosis means celiac is developing and it basically just hasn’t done enough gut damage to be captured on the biopsy yet, and meet that “criteria” to satisfy the current system! Given the overwhelming evidence already - family history, positive ttg and ema. And your own experience and intuition which counts far more. And the labs being reproduced after gluten elimination and reintroduction- elimination and reintroduction diet is the gold standard too. Shame on the Doc and the system. What was the Marsh score? I’m guessing not 0 if it’s potential celiac. Meaning the autoimmune process has been triggered and started. Your daughter is obviously very healthy and her immune system is putting up a good fight. It can take years for the gut damage to build to a point where there’s overt symptoms and then a conclusive diagnosis, hence why many celiacs receive diagnosis later in life. You can prevent it. See the positive and the gift in that. Hopefully the gluten challenge confirms it, but if it doesn’t maybe get a second opinion?
    • cristiana
      How Come Gluten Didnt Bother Me In Italy

      By cristiana · Posted

      @Gigi2025  Thank you for your interesting post.  Some of what you say chimes with something my gastroenterologist tells me - that he has clients who travel to France and find the same as you  - they will eat normal wheat baguette there without issue, for example.  His theory was he thought it might be to do with the locally sourced wheat being different to our own in the UK? But I have to say my own experience has been quite different. I have been to France twice since my diagnosis, and have been quite ill due to what was then (pre-2019)  poor labelling and cross-contamination issues.  My TTG test following my last visit was elevated - 'proof of the pudding', as we say in the UK!  It was not just a case of eating something like, say, shellfish, that disagreed with me - gluten was clearly an issue. I've also been to Italy to visit family a couple of times since my diagnosis.  I did not want to take any chances so kept to my gluten free diet, but whilst there what I did notice is that coeliacs are very well catered for in Italy, and many brands with the same ingredients in the UK are clearly marked on the front of their packaging that they are 'senza glutine'.  In the UK, you would have to find that information in the small print - or it puts people off buying it, so I am told!  So it seems to me the Italians are very coeliac aware - in fact, all children are, I believe, screened for coeliac disease at the age of 6.  That must mean, I guess, that many Italian coeliacs are actively avoiding gluten because, presumably, if they don't, they will fall ill?        
    • deanna1ynne
      Inconclusive results

      By deanna1ynne · Posted

      Thank you both very much. I’m pretty familiar with the various tests, and my older two girls with official dxs have even participated in research on other tests as well. I just felt overwhelmed and shocked that these recent results (which I found pretty dang conclusive after having scott clean labs just six months ago) would still be considered inconclusive. Doc said we could biopsy in another six weeks because my daughter was actually way more upset than I anticipated about the idea of eating it for years before doing another biopsy. It doesn’t hurt her, but she’s afraid of how it may be hurting her in ways she can’t feel. She’s currently eating mini wheats for breakfast, a sandwich with lunch, and a side of pasta along with every dinner, so I’m hoping we’re meeting that 10g benchmark mentioned in that second article!
    • knitty kitty
      Potential celiac need advice

      By knitty kitty · Posted

      Have you tried a genetic test to look for Celiac genes?  No gluten challenge required.  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.