Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Is Igg And Iga Pretty Specific To Celiac?

MamaMeagan

Recommended Posts

MamaMeagan Apprentice
MamaMeagan
Posted

I think the IgA isn't so specific if I remember right. What about the IgG??

Also would Enterolab be much good if you had positive IgG, IgA, but a negative scope. If it matters I think I figured it out very early only had symptoms a couple months, because of some other health problems was looking into it. I was going to do the complete panel, but am thinking since I had some positive blood work it wouldn't be too helpful, maybe just do the gene test?? I plan to ask my GI doctor next week when I see him.

I started the diet about two weeks ago and am finally starting to feel better, is that normal??

Thanks!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


happygirl Collaborator
happygirl
Posted

The AGA IgA and AGA IgG are the least sensitive/specific Celiac tests. Better options are the tTG IgA, EMA IgA, and if you are IgA deficient, the tTG IgG. Newer tests like the DGP IgA/IgG are apparently better options than the AGA tests.

MamaMeagan Apprentice
MamaMeagan
Posted
  • Author

The AGA IgA and AGA IgG are the least sensitive/specific Celiac tests. Better options are the tTG IgA, EMA IgA, and if you are IgA deficient, the tTG IgG. Newer tests like the DGP IgA/IgG are apparently better options than the AGA tests.

So can a positive gliadin IgG Antibody test mean something else then??

My Gliadin IgA was 8M it said <7 is negative 7-10 Equivocal and >10 is positive.

I was just trying to see if these results could mean something else?? However I am responding the diet, it just took longer then I thought to start to feel some change. I mean I felt a little at first, but not much untl just the past couple days.

nora-n Rookie
nora-n
Posted

Dr. Ford explains on his website why antigliadin is importatnt to and does mean something. The GI doctors do not put so much faith in the antigliadin tests because so many patients without villous atrophy have them and they do not know what to do with them....

google ford gluten

Gemini Experienced
Gemini
Posted

Dr. Ford explains on his website why antigliadin is importatnt to and does mean something. The GI doctors do not put so much faith in the antigliadin tests because so many patients without villous atrophy have them and they do not know what to do with them....

google ford gluten

I agree with this and the AGA tests are used for dietary compliance testing after a diagnosis. Many doctors make the mistake of only running the Ttg after a diagnosis and this is not correct....other autoimmune problems can cause elevated Ttg. There may be more, newer tests for diagnosis but the AGA remains the best test for finding out whether you are ingesting gluten unknowingly.

MamaMeagan.....your test was not quite negative but not flamingly positive either. That's when you resort to a dietary trial and, as you are feeling better, you may have to go with this alone for a diagnosis of some kind of gluten problem. You could also continue to eat gluten and see if this spikes higher on future testing but I don't think I would go that route. If the diet made me feel better and alleviates symptoms, that should be enough. As these tests, and most others for celiac, are not ultra sensitive, it can be very hard to discover a problem if you fall into the gluten sensitive category.

MamaMeagan Apprentice
MamaMeagan
Posted
  • Author

So is there a chance this could signal something else besides gluten intolerance?

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,204
    • Most Online (within 30 mins)
      7,748
    JaymeC
    Newest Member
    JaymeC
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • Scott Adams
      Increased intraepithelial lymphocytes after 10 yrs gluten-free

      By Scott Adams · Posted

      Celiac disease is the most likely cause, but here are articles about the other possible causes:    
    • xxnonamexx
      FDA looking for input on Celiac Gluten sensitivity labeling PLEASE READ and submit your suggestions

      By xxnonamexx · Posted

      Please read: https://www.fda.gov/news-events/press-announcements/fda-takes-steps-improve-gluten-ingredient-disclosure-foods?fbclid=IwY2xjawPeXhJleHRuA2FlbQIxMABicmlkETFzaDc3NWRaYzlJOFJ4R0Fic3J0YwZhcHBfaWQQMjIyMDM5MTc4ODIwMDg5MgABHrwuSsw8Be7VNGOrKKWFVbrjmf59SGht05nIALwnjQ0DoGkDDK1doRBDzeeX_aem_GZcRcbhisMTyFUp3YMUU9Q
    • cristiana
      Increased intraepithelial lymphocytes after 10 yrs gluten-free

      By cristiana · Posted

      Hi @Atl222 As @trents points out, there could be many reasons for this biopsy result.  I am interested to know, is your gastroenterologist concerned?  Also, are your blood tests showing steady improvement over the years? I remember when I had my last biopsy, several years after diagnosis, mine came back with with raised lymphocytes but no villous damage, too! In my own case, my consultant wasn't remotely concerned - in fact, he said I might still get this result even if all I ever did was eat nothing but rice and water.   My coeliac blood tests were still steadily improving, albeit slowly, which was reassuring.
    • trents
      Increased intraepithelial lymphocytes after 10 yrs gluten-free

      By trents · Posted

      Welcome to the celiac.com community, @Atl222! Yes, your increased lymphocytes could be in response to oats or it could possibly be cross contamination from gluten that is getting into your diet from some unexpected source but not enough to damage the villi. And I'm certain that increased lymphocytes can be caused by other things besides celiac disease or gluten/oats exposure. See attachment. But you might try eliminating oats to start with and possibly dairy for a few months and then seek another endoscopy/biopsy to see if there was a reduction in lymphocyte counts. 
    • Scott Adams
      Brown Rice Vinegar (organic) from Eden Foods is likely gluten free

      By Scott Adams · Posted

      This is a solid, well-reasoned approach. You’re right that “koji” by itself doesn’t indicate gluten status, and the risk really does come down to which grain is used to culture it. The fact that you directly contacted Eden Foods and received a clear statement that their koji is made from rice only, with no wheat or barley, is meaningful due diligence—especially since Eden has a long-standing reputation for transparency. While the lack of gluten labeling can understandably give pause, manufacturer confirmation like this is often what people rely on for traditionally fermented products. As always, trusting your body after trying it is reasonable, but based on the information you gathered, your conclusion makes sense.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.