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Celiac?


hercules25

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hercules25 Apprentice

Hi Everyone. I am so confused.

Symptoms - nausea, abdom pain, fatigue, vision problems, , tingling in feets and hands, headaches, sore muscles, constipation, bloating,

My CT scans Neg, colonoscopy shows mild inflammation where small intestines and colon meets, MRI scan normal, Gastritis in stomach, etc, etc, LOL

No fever, no bleeding

Normal blood work except:

increased eosinophils (in my blood) my doctor says this indicated to him he thinks my problems are from food allergies but I had the prick food allergy test and negative.

Many of my symptoms do and do not match Chrons disease (per the doctor) but after the test below my dr says he has his doubts but he is gonna treat me for Chrons but none of the meds work. I have read on the internet that this test can also indicate Celiac Disease. My primary dr said he did a celiac panel and it was negative. My Gastro order this test and it came back positive.

Other bloodwork that is positive

Saccharomyces cervissiae, IgG 34.9 High (over 25 is Positive)

Saccharomyces cervissiae, IgA 48.5 High (over 25 is Positive)

I have been sick for 13 years and over it. Any advice would be great.


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Coinkey Apprentice

An easy way to find out if it's gluten related is to go gluten free for a while. I figured out my symptoms were gluten related when I ran out of money (I'm on student loans), which meant I ate all the gluteny products left in my house- leaving me with the potatoes and rice for a week. I felt SO MUCH BETTER after just one week and it finally clicked. I've been gluten free for a month (aside from accidental glutenings and they are HORRIBLE). So, just give it a try and see if anything improves! good luck!

Skylark Collaborator

Yes, all those symptoms can be caused by gluten intolerance. Negative celiac blood tests suggest you don't have severe villous atrophy (which is good!) but they don't say much about gluten intolerance. The next step is to try the gluten-free diet for a few months. If you feel better, you have your answer.

hercules25 Apprentice

Yes, all those symptoms can be caused by gluten intolerance. Negative celiac blood tests suggest you don't have severe villous atrophy (which is good!) but they don't say much about gluten intolerance. The next step is to try the gluten-free diet for a few months. If you feel better, you have your answer.

I am not sure how I would have no damage. Its been 13 years of sick and pain. And a handful of intestinal infections. I am starting to think from the test results it is probably Chrons.

WheatChef Apprentice

I tested negative for IgA-TTg (the main celiac marker) and yet whenever I eat gluten it feels like I have shrapnel dragging through my intestines for a few days. The blood tests don't mean squat compared to how you react to a gluten-free diet.

Marz Enthusiast

Many of my symptoms do and do not match Chrons disease (per the doctor) but after the test below my dr says he has his doubts but he is gonna treat me for Chrons but none of the meds work. I have read on the internet that this test can also indicate Celiac Disease. My primary dr said he did a celiac panel and it was negative. My Gastro order this test and it came back positive.

Hi and welcome :)

Sorry to hear you've struggled with this for so long. :( I'd recommend trying a strict gluten free diet - you have nothing to lose but restricting yourself to certain foods for a few weeks. If you notice a huge impovement, you could let your doctor know about this, and maybe see if you still need the meds? I'm surprised your Gastro didn't recommend this after the panel came back positive?

hercules25 Apprentice

Thanks. I am starting gluten free today. I was not sure if there were 2 different IgA and IgG test. One for Celiac and one for IBD. I guess I am just confused. After the blood test he thought ok lets treat you for Chrons but he has his doubts too. I wonder why he did not talk about Celiac. Maybe its both.


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    • Scott Adams
      This is a very common question, and the most important thing to know is that no, Guinness is not considered safe for individuals with coeliac disease. While it's fascinating to hear anecdotes from other coeliacs who can drink it without immediate issues, this is a risky exception rather than the rule. The core issue is that Guinness is brewed from barley, which contains gluten, and the standard brewing process does not remove the gluten protein to a level safe for coeliacs (below 20ppm). For someone like you who experiences dermatitis herpetiformis, the reaction is particularly significant. DH is triggered by gluten ingestion, even without immediate gastrointestinal symptoms. So, while you may not feel an instant stomach upset, drinking a gluten-containing beer like Guinness could very well provoke a flare-up of your skin condition days later. It would be a gamble with a potentially uncomfortable and long-lasting consequence. Fortunately, there are excellent, certified gluten-free stouts available now that can provide a safe and satisfying alternative without the risk.
    • MogwaiStripe
      Interestingly, this thought occurred to me last night. I did find that there are studies investigating whether vitamin D deficiency can actually trigger celiac disease.  Source: National Institutes of Health https://pmc.ncbi.nlm.nih.gov/articles/PMC7231074/ 
    • Butch68
      Before being diagnosed coeliac I used to love Guinness. Being made from barley it should be something a coeliac shouldn’t drink. But taking to another coeliac and they can drink it with no ill effects and have heard of others who can drink it too.  is this everyone’s experience?  Can I drink it?  I get dermatitis herpetiformis and don’t get instant reactions to gluten so can’t try it to see for myself. 
    • trents
      NCGS does not cause damage to the small bowel villi so, if indeed you were not skimping on gluten when you had the antibody blood testing done, it is likely you have celiac disease.
    • Scott Adams
      I will assume you did the gluten challenge properly and were eating a lot of gluten daily for 6-8 weeks before your test, but if not, that could be the issue. You can still have celiac disease with negative blood test results, although it's not as common:  Clinical and genetic profile of patients with seronegative coeliac disease: the natural history and response to gluten-free diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606118/  Seronegative Celiac Disease - A Challenging Case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441776/  Enteropathies with villous atrophy but negative coeliac serology in adults: current issues: https://pubmed.ncbi.nlm.nih.gov/34764141/  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.
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