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Enterolab Results Are Back. I Have Some ?s


kaygato

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kaygato Explorer

I haven't posted in a while because I haven't had anything to say. Here are my lab results:

Fecal Ant-gliadin IgA 14 units(normal range is less than 10 units)

Fecal Anti-casein(cow's milk IgA) 6 units (normal range is less than 10 units)

Fecal Anti-ovalbumin(chicken egg) IgA 17 units (normal range is less than 10 units)

Fecal Anti-soy IgA 5 units (normal range is less than 10 units)

HLA-DQB1 Molecular analysis, Allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0301

Serologic eqivalent: HLA-DQ 3,3 (Subtype 8,7)

I have one of the main genes that predisposes to gluten sensitivity and celiac sprue. I also have a non-celiac gene predispoing to gluten sensitivity.

I guess I'm a little overwhemed and don't know where to start. I went to college away from home last year as a freshman and almost failed out (2nd semester was quite rough). So I'm living at home and taking classes locally for a while.

I recently asked to be tested for thyroid disease (since a lot of women on one side of a family have problems with it), and I found out I have hashimoto's. My thyroid isn't dead yet, though, but I'd say it's not optimal. I'm going to go to a doctor who works with thyroid patients to treat my thyroid. I'm also curious to see if I also have a high amount of grave's antibodies, like I do with the tpo antibodies.

I've always had problems with motivation, attention, some anhedonia, and kind of a lack of energy/depression, oh and some ocd-ish habits to go along with that. However, this has gotten worse with age, it especially got worse around 14 and I started struggling more in school and felt more depressed. I also have pretty bad female sexual dysfuntion.

I'm just wondering where to go from here. I was really hoping eggs wouldn't be a problem for me, but it looks like they are. And whatabout the casein and soy? Might I still have problems with those even thouth the antibodies are normal? I've read that after eliminating gluten people sometimes discover intolerances to other foods, like dairy and soy.

I'm going to try and makes the dietary changes gradually, and eventually completely elminate some things. I luckily have supportive parents who are letting me live at home and take classes part time while I try and get better (although they still want me to get a job sometime during this next school year).

I guess I need advice on interpreting my results and what I should eliminate. I also am curious if any of you have mainly psychological issues and not physical ones (which is my problem). I'm also on antidepressantsbut they aren't working that well yet.

Sorry this was so long...


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starrytrekchic Apprentice

Don't change your diet gradually! That may actually increase your misery, as your body starts reacting more strongly to smaller amounts of aggravating foods. Don't worry about soy or casein. Do cut out gluten and eggs (you may be able to reintroduce eggs in 6 months or so). Otherwise, try to get a healthy selection of food (you probably don't want to go overboard on any particular area) and let your body heal.

I had equal parts physical and psychological problems, and psychologically I've certainly evened out. It took a while, but I got there.

RollingAlong Explorer

My spouse eliminated eggs for about a year, the first time he challenged them, his main reaction was a pronounced negative mood that seemed to last most of the day. He had mood/motivation issues before going gluten free; the digestive stuff came after he went gluten free. So now, if he makes a mistake, he is edgy, anxious with D and then heartburn for about 2 days. It used to be longer, but the cleaner his is, and the longer, the better he's getting. Hope this is helpful to you.

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
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