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Why Has My Gliadin Igg Raised After 7 Months Gluten-Free?


seattlejoy

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seattlejoy Rookie

I was diagnosed with Celiac after blood and biopsy in May 2012. I keep mulling over my December results after being obsessively gluten free. My whole family and household is gluten free, I cook from scratch and rarely ever eat out unless I have spoken to manager and chef. I'm very aware of hidden gluten and believe I am doing a great job but my Gliadin IgG has raised...

TT IgA went from 129.6 to 4.5

Gliadin IgA went from 113.8 to 22.1

Gliadin IgG went from 57.7 to 131.9

My doctor didn't say much about it but I don't think she is that familiar with these tests either.

Can anyone help me figutre out what this means?

Thank you!


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GottaSki Mentor

That is interesting. Since both IgA tests went down substantially -- it is puzzling.

Did they run a tTG IgG? Any change there?

Since it is a surpising number - I think I'd have it re-run to make sure it was an accurate result.

Looks like you are doing well on removing gluten, otherwise the other numbers would not have fallen so.

How about symptom improvement?

Are you feeling better?

seattlejoy Rookie

That is interesting. Since both IgA tests went down substantially -- it is puzzling.

Did they run a tTG IgG? Any change there?

Since it is a surpising number - I think I'd have it re-run to make sure it was an accurate result.

Looks like you are doing well on removing gluten, otherwise the other numbers would not have fallen so.

How about symptom improvement?

Are you feeling better?

Thanks for asking! I don't see a tTG IgG. I feel better than I did before diagnosis but I definitely don't feel great. I have had all my food sensitivities and allergies ran (IgG and IgE). I am seeing a specialist, Dr. Wangen next month.

GottaSki Mentor

Thanks for asking! I don't see a tTG IgG. I feel better than I did before diagnosis but I definitely don't feel great. I have had all my food sensitivities and allergies ran (IgG and IgE). I am seeing a specialist, Dr. Wangen next month.

Glad you'll be seeing a specialist.

I'm still curious.....

What symptoms have improved?

What symptoms have remained or changed?

dilettantesteph Collaborator

Are you using gluten free flours? They can be problematic for some. Do you use one that is tested to below 5 ppm? Have you been keeping a food/symptom journal? I do that and try to make only one change per week so that I can track the source of any problems that I am having. If I am having current problems I will eliminate foods in my diet one by one to check them.

  • 3 weeks later...
eers03 Explorer

I have been on the diet since November of last year. My gliadin IGG has gone up a little since my gluten-free diet. I'm not real worried because 1.) I have caught a couple weak spots where I was being glutened some unintentionally and 2.) it seems like I have read about others who have had the numbers continue to go up or stay the same for the first year before they start to drop. I'm assuming its one of these categories that I fall into. You're not alone!

frieze Community Regular

I was diagnosed with Celiac after blood and biopsy in May 2012. I keep mulling over my December results after being obsessively gluten free. My whole family and household is gluten free, I cook from scratch and rarely ever eat out unless I have spoken to manager and chef. I'm very aware of hidden gluten and believe I am doing a great job but my Gliadin IgG has raised...

TT IgA went from 129.6 to 4.5

Gliadin IgA went from 113.8 to 22.1

Gliadin IgG went from 57.7 to 131.9

My doctor didn't say much about it but I don't think she is that familiar with these tests either.

Can anyone help me figutre out what this means?

Thank you!

Did you have a GI "bug" shortly before this was drawn?

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
    • Seaperky
      I found at Disney springs and Disney they have specialist that when told about dietary restrictions they come and talk to you ,explain cross contamination measures tsken and work with you on choices. Its the one place I dont worry once I've explained I have celiac disease.  Thier gluten free options are awesome.
    • Churley
      Have you tried Pure Encapsulations supplements? This is a brand my doctor recommends for me. I have no issues with this brand.
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