Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Test Interpretation?

shihtzujane

Recommended Posts

shihtzujane Newbie
shihtzujane
Posted

Just got genetic testing fm Mayo.  Allergy blood tests done yrs ago showed I was allergic to glutens, so I went gluten-free then.  After that, osteporosis doc was looking for why I got osteoporosis at an early age, he found antibodies.  GI doc did endoscopy, which was okay, he said maybe b/c I had been gluten-free so long (although he had me start on gluten about 6 weeks prior to the test).  My niece was just diagnosed 6 months ago.  New GI dr. ran following...  DQ Alpha 1  01:02, 05:01    DQ Alpha 2  02:01, 06:02  Celiac gene pairs present?  Yes.  I'm thinking these are postive results, right?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


SMRI Collaborator
SMRI
Posted

Gene testing just means you have the genetic make up for Celiacs but it does not mean you have celiac for sure.  Are they going to do bloodwork for the actual Celiac testing since you went back on Gluten?  

shihtzujane Newbie
shihtzujane
Posted
  • Author

I'm not sure what you mean.  I haven't gone back on gluten.  The blood tests before showed the antibodies, the GI dr. didn't feel it was necessary to repeat those tests.

kareng Grand Master
kareng
Posted

If you had a positive celiac test before, you have Celiac. If you had allergy testing, you did not test for Celiac. This may just be a confusion of word usage? I am not sure why you would be re- tested for Celiac if you were tested for it before.

Edit : your dogs are adorable!

shihtzujane Newbie
shihtzujane
Posted
  • Author

I've had three forms of blood tests that relate to gluten.  Years ago, glutens tested positive when I had allergy blood testing.  Then, a couple of years after that, when my gyn was running blood tests, looking for possible reasons for my early-onset osteoporosis, the one test that was positive was one that showed antibodies for celiac.  Then, I had this latest genetic testing which I can't interpret the results of. 

nvsmom Community Regular
nvsmom
Posted

Welcome to the board.  :)

 

For genetic tests that place one in the high risk group for celiac disease are the DQ2 and DQ8 genes.  It looks like you have the DQ2 gene which means you are one of the 30% of the world's population who is at an increased risk of having celiac disease.  I think it is somewhere around 97% of all celiacs have the DQ2 or DQ8 genes.

 

I'm not sure why the doctor ran the genetic test for celiac disease on you since you said you positively tested for the autoantibodies found in celiacs - usually the tissue transglutaminase, endomysial antibodies, or the deaminated gliadin peptides tests. If one of those is positive, you have a gluten sensitivity that took the form of celiac disease, which is an autoimmune disesse that can run in families.  There is not any real need to do the genetic tests if one of those is positive. Even if the endoscopic biopsy is negative (intestinal damage is missed in up to 20% of celiacs) you still have celiac disease.

 

Medically speaking, there is not actually an allergy to gluten.  People can have a sensitivity to gluten, or they can be allergic to things that contain gluten like wheat, but a gluten allergy does not really exist.  An allergy is an IgE reaction and gluten doesn't cause that.

 

And kudos to your doctor for thinking of celiac disease when you presented with early osteoarthritis.  Not many doctors would have made that connection.

Solandra Rookie
Solandra
Posted

I would say you have Celiac by the test results, the genes, and the fact that you developed Osteoporosis early. 6 weeks of gluten prior to an endoscopy isn't enough.. They usually have you shoot for 12, so that's probably why they didn't see any damage. I'd keep going gluten free if I were you.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


shihtzujane Newbie
shihtzujane
Posted
  • Author

Thanks, everyone.  And, interestingly (and maybe why my newish GI ran the genetic testing), my 21-year-old niece was just diagnosed with celiac a few months ago. 

SMRI Collaborator
SMRI
Posted

I'm not sure what you mean.  I haven't gone back on gluten.  The blood tests before showed the antibodies, the GI dr. didn't feel it was necessary to repeat those tests.

 

You said in your first post that your GI had you go back on Gluten 6 weeks before your scope.  We would have to see your actual tests and results to give you better answers but like other's have said, the allergy testing is not Celiac testing.  Can you get your results from before?

cyclinglady Grand Master
cyclinglady
Posted

Welcome!

Wow, what are you doing for the Osteoporosis? If you were gluten free for all those years, how did the osteoporosis develop? Perhaps, you were not as gluten free as you thought. Cross contamination is a big issue. I highly recommend reading our Newbie 101 section under the "Coping" section of this forum.

Here is the link:

https://www.celiac.com/forums/topic/91878-newbie-info-101/

Take care!

shihtzujane Newbie
shihtzujane
Posted
  • Author

You said in your first post that your GI had you go back on Gluten 6 weeks before your scope.  We would have to see your actual tests and results to give you better answers but like other's have said, the allergy testing is not Celiac testing.  Can you get your results from before? 

Do you mean the test the gynecologist ran?

kareng Grand Master
kareng
Posted

Just got genetic testing fm Mayo.  Allergy blood tests done yrs ago showed I was allergic to glutens, so I went gluten-free then.  After that, osteporosis doc was looking for why I got osteoporosis at an early age, he found antibodies.  GI doc did endoscopy, which was okay, he said maybe b/c I had been gluten-free so long (although he had me start on gluten about 6 weeks prior to the test).  My niece was just diagnosed 6 months ago.  New GI dr. ran following...  DQ Alpha 1  01:02, 05:01    DQ Alpha 2  02:01, 06:02  Celiac gene pairs present?  Yes.  I'm thinking these are postive results, right?

 

 

Do you mean the test the gynecologist ran?

 

 

I am getting confused.  Maybe start over?  Why would the GI put you on a gluten challenge if you were diagnosed years ago?  Did he run any blood work after you were eating gluten?  If you had been gluten free for years - the Celiac blood work shouldn't have been positive (the one the OB?GYN ran?).  

 

 

You may want to get a copy of all your medical records to see if you were actually tested for Celiac or not.  It sounds like you probably have it but a genetic test only tells you that you are 1 of the 30% of people with a gene that could be activated at some time (but for most, will not be activated as only about 1% of the population have Celiac Disease).

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,694
    • Most Online (within 30 mins)
      7,748
    VJM
    Newest Member
    VJM
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Gigi2025
      How Come Gluten Didnt Bother Me In Italy

      By Gigi2025 · Posted

      Since 2015 we've spent extensive time in Italy and I've been able to eat their wheat products without incident. Initially, I was practically starving thinking foods in Sicily were not gluten-free.  An Italian friend who had lived in the US for over 20 years said she had celiac/gluten-free friends from the US who could eat Italian wheat products without problems. Hesitantly, I tried little by little without issues.  A few years later at a market, I asked a bread vendor if they had gluten-free loaves. Turns out she had lived in LA, said groups believe it's not the gluten that's causing our bodies harm, but potassium bromate; these groups have been trying to ban it.  Bromines and other halogens wreaks havoc to our endocrine system and, more specifically, our thyroids and immune systems. When bromines are ingested/absorbed into the body, it displaces iodine causing other health issues. Potassium bromate is a powerful oxidizing agent (dough 'conditioner') that chemically changes flour to enhance elasticity, bleaches the dough, and ages the flour much faster than open air.   Shortly thereafter while visiting friends in California, one family said they had gone gluten-free and the difference was incredible. The reason they choose this path was due them (a biologist/chemist/agriculturist scientist) having to write a portion of a paper about a certain product for the company he worked. Another company's scientist was directed to write the other portion. All was confidential, they weren't allowed to know the other company/employee.  After the research, they learned gluten was being removed from wheat, sent elsewhere, returned in large congealed blocks resembling tofu, and then added to wheat products. Potassium bromate has been banned for use in Europe, China, and other countries, but not in the US. Then we have the issues of shelf preservatives and stabilizers. What are we eating?  Why? We spend long periods of time in Italy and all has been good.  We just returned from an extended time in Greece;  no issues there either.  There is a man there we learned about on a travel show about Greece who walks the hills, picking herbs, pods, etc.  He is a very learned scholar, taught at the university level in Melbourne. It took a few days to locate him, but were finally successful. He too, is concerned about the additives and preservatives in American food (many of his customers are Americans, haven't been in the best of health, and have become healthier after visiting him). He suggested taking a food product from the US and the same product in Europe, and compare the different ingredients. Then ask why these things are being allowed in the US by the 'watch dog' of our foods and drugs. It would be amuzing if it weren't tragic. I'm presently looking for flour from Europe that I can make my own bread and pasta as the gluten-free bread is now $7.99 a (small) loaf.  BTW, studies are showing that many gluten-free individuals are becoming diabetic. My guess is because the gluten-free products are high in carbs. This is only my experience and opinion garnished by my personal research.  I hope it helps.  
    • knitty kitty
      Taking Probiotics but Still Getting Sick After Gluten – Advice?

      By knitty kitty · Posted

      Symptoms that get worse if you don't supplement is a sign of malabsorption, possibly due to Celiac disease. Blood tests for nutritional deficiencies are not very accurate, and should be done when you have been off of supplements for eight to twelve weeks, otherwise the vitamin supplements you've taken will be measured.  The blood circulation system is a transportation system.  It transports the vitamins you've absorbed around the body, but blood tests don't give an accurate picture of the vitamin and mineral stores inside organs and tissues where they are actually used.  You can have "normal" blood levels but still have deficiencies.  This is because the brain demands stored nutrients be put into the blood stream to supply important organs, like the brain and heart, while other organs do without.   If you are taking Thiamine Mononitrate in your supplements, you are probably low in thiamine.  Thiamine Mononitrate is used in many supplements because it won't break down sitting on a shelf.  This also means Thiamine Mononitrate is difficult for the body to utilize.  Only thirty percent of Thiamine Mononitrate on the label is absorbed and even less is able to be utilized by the body.  A different form of Thiamine called Benfotiamine has been shown to promote intestinal healing.   Talk to your doctor about doing a genetic test to look for Celiac markers.   I'm concerned that if you do a gluten challenge (10 grams of gluten per day for a minimum off two weeks) in your weakened state, the nutritional deficiencies will become worse and possibly life threatening.  
    • ElisaAllergiesgluten
      Allergy medication: cetirizine by the HealthA2Z is it gluten free?

      By ElisaAllergiesgluten · Posted

      Hello, good afternoon!   I apologize, I didn’t see a notification and I’m just reading this. Thank you so much for sharing your thoughts and the link. Yes you are absolutely right, even so trying to get a response from them has been extremely difficult. They don’t answer but I will your practice of “guilty until proven innocent.”   I like and have a sense of trust here in this website, everyone is honest and thoughts are raw. The mutual understanding is amazing!   thank you Scott!
    • Scott Adams
      Draft gluten-free ciders… can they be trusted ?

      By Scott Adams · Posted

      I'd go with a vodka tonic, but that's just me😉
    • Rejoicephd
      Draft gluten-free ciders… can they be trusted ?

      By Rejoicephd · Posted

      That and my nutritionist also said that drinking cider is one of the worst drink choices for me, given that I have candida overgrowth.  She said the combination of the alcohol and sugar would be very likely to worsen my candida problem.  She suggested that if I drink, I go for clear vodka, either neat or with a splash of cranberry.   So in summary, I am giving ciders a rest.  Whether it's a gluten risk or sugars and yeast overgrowth, its just not worth it.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.