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Question About Slightly Elevated Bilirubin & Ana


glutenfreemomma188

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glutenfreemomma188 Apprentice

Good afternoon everyone. 

It has been a while since the last time I made a message on here. 

I have a quick question for you guys and was hoping some of you could answer it for me. 

 

Back in May of 2014 I had to undergo a gluten challenge and have a biopsy done to confirm Celiacs.

It was soon after the result came back that I found out that I have it 100%.  Last month I tested my blood after

being on a gluten free diet for 6 months and my IGA was at 1.1 U/mL & my IGG was at 12.0 U/mL standard range was: 

 IGA  0-3.9 U/mL   & IGG 0-5.9 U/mL, 

 

This month I took the test again along with a check of my Bilirubin because that has been slightly elevated along with my Ana pretty much since I found out I had celiacs. My Ana has been slightly elevated since 2008 and I got the blood test done for celiacs back in 2012.

 

This is the result of the blood test again:

IGA 1.0 U/mL  & IGG 9.0 U/mL. 

This last reading shows me that I am healing with this gluten free diet I am on but the IGG is taking a lot longer to heal. However, it

has went down by 3 points which is fantastic. 

 

Now I still have a concern about my bilirubin being slightly higher & my Ana. 

On my test it says: (Bilirubin Direct) standard range is: 0.0-0.2mg/dL  and I am at: 0.3 (& Both ALT & AST ARE PERFECT)

(Bilirubin Total) standard range is: 0.2-1.3mg/dL and my value is 1.3 (which is still in the standard range right?).

My Ana is at: 1.1 and standard range is: 1.0 (So like I said, barely elevated but still slightly). 

Back in 2008 before I found out I had celiacs my ana was at: 1.2 and since going on the g.f. diet It has leveled off at 1.1 and stayed there from 11/27/2013 - 2/4/2014 (to present). 

 

Now that you know the exact numbers, here is my question: 

 

Can having celiacs and healing from it cause your bilirubin & Ana to be slightly elevated?. 

 

Thank you in advance, just need a peace of mind guys!

 

P.s. Had a lupus test done and that was negative! 


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LauraTX Rising Star

Great to hear you are healing up!  The body has much more IGG than IGA, so in general the IGG number is going to stay higher as they go down.  Great progress so far on it!

 

What has your doctor said about the ANA and the bilirubin?  It is good to hear that the lupus test was negative... have you seen a rheumatologist?  Open Original Shared Link, however there isn't much known about it.  But given that it is going down as you heal, I would give both blood values more time to normalize as your body heals from the Celiac damage. 

  • 2 weeks later...
glutenfreemomma188 Apprentice

Thank you for your reply. :) 

Gemini Experienced

I wouldn't sweat either test.  ANA is often elevated with any autoimmune disease (mine is much higher but I have 4 AI diseases).  I do not know much about bilirubin but your numbers are so close to normal I would not even worry about it.  You are healing!

glutenfreemomma188 Apprentice

Thank you so much guys. This gives me a peace of mind. :)

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
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      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
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      I found at Disney springs and Disney they have specialist that when told about dietary restrictions they come and talk to you ,explain cross contamination measures tsken and work with you on choices. Its the one place I dont worry once I've explained I have celiac disease.  Thier gluten free options are awesome.
    • Churley
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