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Question About Slightly Elevated Bilirubin & Ana


glutenfreemomma188

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glutenfreemomma188 Apprentice

Good afternoon everyone. 

It has been a while since the last time I made a message on here. 

I have a quick question for you guys and was hoping some of you could answer it for me. 

 

Back in May of 2014 I had to undergo a gluten challenge and have a biopsy done to confirm Celiacs.

It was soon after the result came back that I found out that I have it 100%.  Last month I tested my blood after

being on a gluten free diet for 6 months and my IGA was at 1.1 U/mL & my IGG was at 12.0 U/mL standard range was: 

 IGA  0-3.9 U/mL   & IGG 0-5.9 U/mL, 

 

This month I took the test again along with a check of my Bilirubin because that has been slightly elevated along with my Ana pretty much since I found out I had celiacs. My Ana has been slightly elevated since 2008 and I got the blood test done for celiacs back in 2012.

 

This is the result of the blood test again:

IGA 1.0 U/mL  & IGG 9.0 U/mL. 

This last reading shows me that I am healing with this gluten free diet I am on but the IGG is taking a lot longer to heal. However, it

has went down by 3 points which is fantastic. 

 

Now I still have a concern about my bilirubin being slightly higher & my Ana. 

On my test it says: (Bilirubin Direct) standard range is: 0.0-0.2mg/dL  and I am at: 0.3 (& Both ALT & AST ARE PERFECT)

(Bilirubin Total) standard range is: 0.2-1.3mg/dL and my value is 1.3 (which is still in the standard range right?).

My Ana is at: 1.1 and standard range is: 1.0 (So like I said, barely elevated but still slightly). 

Back in 2008 before I found out I had celiacs my ana was at: 1.2 and since going on the g.f. diet It has leveled off at 1.1 and stayed there from 11/27/2013 - 2/4/2014 (to present). 

 

Now that you know the exact numbers, here is my question: 

 

Can having celiacs and healing from it cause your bilirubin & Ana to be slightly elevated?. 

 

Thank you in advance, just need a peace of mind guys!

 

P.s. Had a lupus test done and that was negative! 


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LauraTX Rising Star

Great to hear you are healing up!  The body has much more IGG than IGA, so in general the IGG number is going to stay higher as they go down.  Great progress so far on it!

 

What has your doctor said about the ANA and the bilirubin?  It is good to hear that the lupus test was negative... have you seen a rheumatologist?  Open Original Shared Link, however there isn't much known about it.  But given that it is going down as you heal, I would give both blood values more time to normalize as your body heals from the Celiac damage. 

  • 2 weeks later...
glutenfreemomma188 Apprentice

Thank you for your reply. :) 

Gemini Experienced

I wouldn't sweat either test.  ANA is often elevated with any autoimmune disease (mine is much higher but I have 4 AI diseases).  I do not know much about bilirubin but your numbers are so close to normal I would not even worry about it.  You are healing!

glutenfreemomma188 Apprentice

Thank you so much guys. This gives me a peace of mind. :)

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    • trents
      So the tTG-IGA at 28 is positive for celiac disease. There are some other medical conditions that can cause elevated tTG-IGA but this is unlikely. There are some people for whom the dairy protein casein can cause this but by far the most likely cause is celiac disease. Especially when your small bowel lining is "scalloped". Your Serum IGA 01 (aka, "total IGA") at 245 mg/dl is within normal range, indicating you are not IGA deficient. But I also think it would be wise to take your doctor's advice about the sucraid diet and avoiding dairy . . . at least until you experience healing and your gut has had a chance to heal, which can take around two years. After that, you can experiment with adding dairy back in and monitor symptoms. By the way, if you want the protein afforded by dairy but need to avoid casein, you can do so with whey protein powder. Whey is the other major protein in dairy.
    • jenniber
      hi, i want to say thank you to you and @trents   . after 2 phone calls to my GI, her office called me back to tell me that a blood test was “unnecessary” and that we should “follow the gold standard” and since my biopsy did not indicate celiac, to follow the no dairy and sucraid diet. i luckily have expendable income and made an appt for the labcorp blood test that day. i just got my results back and it indicates celiac disease i think 😭   im honestly happy bc now i KNOW and i can go gluten free. and i am SO MAD at this doctor for dismissing me for a simple blood test that wouldn’t have cost her anything !!!!!!!!!!! im sorry, im so emotional right now, i have been sick my whole life and never knew why, i feel so much better already   my results from labcorp:   Celiac Ab tTG TIgA w/Rflx Test Current Result and Flag Previous Result and Date Units Reference Interval t-Transglutaminase (tTG) IgA 01 28 High U/mL 0-3 Negative 0 - 3 Weak Positive 4 - 10 Positive >10 Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy. Immunoglobulin A, Qn, Serum 01 245 mg/dL 87-352
    • JoJo0611
      Thank you this really helped. 
    • Samanthaeileen1
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    • GlorietaKaro
      One doctor suggested it, but then seemed irritated when I asked follow-up questions. Oh well—
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