Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Basic Celiac Question


StClair

Recommended Posts

StClair Apprentice

I hope I can ask this clearly. Do migraines, joint problems, osteoporosis, anxiety (I'm newly diagnosed celiac and have all of these), and the like, all come from gut problems, malabsorption, etc? In other words, since gluten causes an autoimmune reaction in the intestines, does it also get into the bloodstream and cause an autoimmune reaction in the brain, joints, bones, etc, or are all these problems caused secondarily by malabsorption/vitamin deficiencies in the gut?

Sorry if my question is not clear! I'm so curious about what has been happening in my body all these years.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



RMJ Mentor

The autoimmune reaction starts in the gut, but those antibodies get into the bloodstream and circulate around the whole body. I don't think the biological mechanisms for all of the problems that can be seen in celiacs are known.

nvsmom Community Regular

Many problems can come from the inflammation it causes as well.

 

I don't completely believe that the damaged intestines is the sole cause of vitamin deficiencies and malabsorption.  I am certain that I had celiac disease my entire life, yet I had no vitamin or malabsoption issues even though I am sure I had extensive gut damage.  I guess the damaged intestines do have an impact on those who suffer from those symptoms, but it can't be the only reason it happens or we would all have those symptoms.  KWIM?

 

I don't think "they" really know why it causes such problems yet.  With less than 1% of the population having celiac disease, and it not requiring any medication to treat it, I don't think they do much research into it.  Money wise, it isn't worth it.

Jays911 Contributor

If you think the medical community understands celiac disease or gluten issues, I have a bridge in Brooklyn to sell. What I do know is that since going gluten free, my life has improved immeasurably in manifold ways. No more depression or anxiety. I sleep better. No more snoring. No more gut aches. No more coughing.

StClair Apprentice

It's an eye-opener how little research there is, unless I am not looking int the right places.  I guess there are not enough of us to justify funding.  My curiosity is intense, but I guess I'll have to get used to not understanding certain things.  Not the only area of life this is true for, I guess.   I'll take the improved heath, though, whether I understand it or not!

  • 5 weeks later...
BoJonJovi Newbie

There are more neural connections in the gut than there is in the brain. These connections control a whole host of biochemical reactions throughout the body and endocrine system. Any damage in the GI tract can manifest itself in other parts of the body and definitely will effect your health, the way you feel and how chemical messengers tell your body what to do. 

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      130,247
    • Most Online (within 30 mins)
      7,748

    Jbamf8791
    Newest Member
    Jbamf8791
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):




  • Who's Online (See full list)


  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • knitty kitty
      @Zuma888, The antibodies produced in response to gluten are made in the intestines.  When the body is provoked sufficiently, the antibodies overflow out of the intestines and into the blood stream.  Once in the blood stream, the antibodies can be measured with tTg IgA tests.  Three grams of gluten per day for two weeks minimum is enough gluten to make you feel the symptoms of having been glutened, but the antibodies are not in sufficient quantity to be measured in the blood. Ten grams of gluten per day for a minimum of two weeks is required to get the anti gluten antibodies at a high enough level in the blood stream to be measured by tTg IgA tests. So, no, occasional cross...
    • Scott Adams
      No, I would not say this at all. If you were diagnosed with celiac disease and were gluten-free for a while, you could have gone into remission. Everyone's body is different, and some celiacs may be able to get regular contamination and not end up with damaged villi and positive antibody tests, while others who ingest tiny amounts will relapse and have full blown symptoms and flattened villi.  Only a full gluten challenge would reveal where you are at this point. Here is more info about how to do a gluten challenge for a celiac disease blood panel, or for an endoscopy: and this recent study recommends 4-6 slices of wheat bread per day:    
    • Scott Adams
      The most common nutrient deficiencies associated with celiac disease that may lead to testing for the condition include iron, vitamin D, folate (vitamin B9), vitamin B12, calcium, zinc, and magnesium.  Unfortunately many doctors, including my own doctor at the time, don't do extensive follow up testing for a broad range of nutrient deficiencies, nor recommend that those just diagnosed with celiac disease take a broad spectrum vitamin/mineral supplement, which would greatly benefit most, if not all, newly diagnosed celiacs.      
    • Pablohoyasaxa
      Great  post. The skin issue can be intolerable. I have been taking niacinamide for the past month and have improved with respect to the blistering lesions. 
    • knitty kitty
      I've found taking Niacin Vitamin B 3 in the form that causes flushing (nicotinic acid) helps immensely to clear my skin.  The flushing is harmless and goes away the longer Niacin is taken.  The flushing (vasodilation in the skin) helps the body get rid of the tTg 3 IgA antibodies that cause the blisters.  TTg 2 IgA antibodies are found in the blood and are measured in diagnostic testing for Celiac.  People with Dermatitis Herpetiformis make tTg 3 as well as tTg 2 antibodies.  Niacin Vitamin B3 in the non flushing form niacinamide also works without the flushing, but takes a bit longer.   I also avoid foods containing high levels of iodine because iodine activates the tTg 3 IgA antibodies to...
×
×
  • Create New...