Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

IgA deficiency


Thrillrose

Recommended Posts

Thrillrose Rookie

Hello, 

Two of my children have been diagnosed with coeliac disease. I was tested as well and my TT IgA and deamidated gliadin were both normal but the IgA was deficient. 

My dr said that doesn't mean much. But then my sister was tested and her result was the same as mine! Her dr told her to cut out gluten as she obviously has a reaction to it. 

And then of course I start googling and find out that her dr seems to be correct. And that if we don't cut out gluten now, coeliac disease may develop. 

Does anyone know any more about this??

 

thanks 

 

 

 


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



cyclinglady Grand Master

If you are iga deficient, then any of the iGA-based celiac tests (e.g. DGP Iga or TTg iga) are invalid.  Your doctor can order other celiac antibody tests: EMA or the tTG IgG or DGP IGG).  It sounds like your doctor only ordered then iga versions.  Not good, in your case because of your igA defciency.  

Open Original Shared Link

Welcome to the forum!  

 

 

  • 2 weeks later...
Nolev Newbie

Totally agree with cyclinglady. I am IgA deficient as well. Scores a healthy zero on the IgA based tests - false negative as it turns out. Finally got the TTG-IgG version and voila I broke the test - really. >15 was positive for celiac and I had >250!! IgA deficiency is genetic. You need to follow this chart and you can see clearly what tests you need. Good luck. Open Original Shared Link

Nolev Newbie

Oh and let me clarify - based on the tests you say you had you only know you are IgA deficient. You have no information on your celiac diagnosis until you take the IgG versions. Then you will know if you likely have celiac or not. Next step would be endoscopy. If you have celiac, you need to be gluten-free for life. You don't develop celiac by eating gluten. You simply get much much worse and proceed to damage your intestines and put yourself at risk for other diseases such as lymphoma and diabetes. You would already have celiac if the TTG-IgG test comes back positive, if that makes sense. Then the gluten-free diet reverses the symptoms. Hope that helps clarify 

Thrillrose Rookie

Great info! Thanks so much. 

Irene Joanne Explorer

I am deficient in IGA- thankfully the lab that processed my lab work- also did the IgG blood work. This was positive as well as the biopsy. 

 

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - Rejoicephd replied to Rejoicephd's topic in Coping with Celiac Disease
      8

      Draft gluten-free ciders… can they be trusted ?

    2. - Wends replied to deanna1ynne's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      9

      Inconclusive results

    3. - deanna1ynne replied to deanna1ynne's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      9

      Inconclusive results

    4. - Gigi2025 replied to Leeloff's topic in Gluten-Free Foods, Products, Shopping & Medications
      64

      How Come Gluten Didnt Bother Me In Italy

    5. - Wends replied to deanna1ynne's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      9

      Inconclusive results


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,711
    • Most Online (within 30 mins)
      7,748

    new journey
    Newest Member
    new journey
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Rejoicephd
      @Scott Adams That's actually exactly what I ended up asking for— vodka tonic with Titos.  I saw on their website that Tito's is certified gluten-free (maybe many of the clear vodkas are, I don't know, I just happened to look up Tito's in advance). I should have actually specified the 'splash' though, because I think with the amount of tonic she put in there, it did still end up fairly sweet.  Anyway, I think I've almost got this drink order down!
    • Wends
      Be interesting to see the effects of dairy reintroduction with gluten. As well as milk protein sensitivity in and of itself the casein part particularly has been shown to mimic gluten in about 50% of celiacs. Keep us posted!
    • deanna1ynne
      She has been dairy free for six years, so she’d already been dairy free for two years at her last testing and was dairy free for the entire gluten challenge this year as well (that had positive results). However, now that we’re doing another biopsy in six weeks, we decided to do everything we can to try to “see” the effects, so we decided this past week to add back in dairy temporarily for breakfast (milk and cereal combo like you said).
    • Gigi2025
      Hi Christiana, Many thanks for your response.  Interestingly, I too cannot eat wheat in France without feeling effects (much less than in the US, but won't indulge nonetheless).  I also understand children are screened for celiac in Italy prior to starting their education. Wise idea as it seems my grandson has the beginning symptoms (several celiacs in his dad's family), but parents continue to think he's just being difficult.  Argh.  There's a test I took that diagnosed gluten sensitivity in 2014 via Entero Labs, and am planning on having done again.  Truth be told, I'm hoping it's the bromine/additives/preservatives as I miss breads and pastas terribly when home here in the states!  Be well and here's to our guts healing ❤️
    • Wends
      Lol that’s so true! Hope you get clarity, it’s tough when there’s doubt. There’s so much known about celiac disease with all the scientific research that’s been done so far yet practically and clinically there’s also so much unknown, still. Out of curiosity what’s her dairy consumption like? Even compared to early years to now? Has that changed? Calcium is dependent in the mechanism of antigen presenting cells in the gut. High calcium foods with gluten grains can initiate inflammation greater.  This is why breakfast cereals and milk combo long term can be a ticking time bomb for genetically susceptible celiacs (not a scientific statement by any means but my current personal opinion based on reasoning at present). Milk and wheat are the top culprits for food sensitivity. Especially in childhood. There are also patient cases of antibodies normalising in celiac children who had milk protein intolerance/ delayed type allergy. Some asymptomatic. There were a couple of cases of suspected celiacs that turned out to have milk protein intolerance that normalised antibodies on a gluten containing diet. Then there were others that only normalised antibodies once gluten and milk was eliminated. Milk kept the antibodies positive. Celiac disease is complicated to say the least.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.