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Blood test results back


Binti1962

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Binti1962 Rookie

Hi, again.  I posted previously about my biopsy.  Got my labs for blood work back, and I don't think the Doctor requested a "panel" only Immunogloubin A which was 99 out ot a range of 81-463, and Tissue transglutaminase AB, IGA which was 1.  No antibodies detected.  Do I need to have done more blood tests, or is this sufficient?  He still says the biopsy indicates celiac, but told me that since these two tests were normal that I dont have celiac.  He's just overlooking the biopsy since it was mild.  Should I see a celiac specialist?  I should add that I had only been eating gluten for 3 weeks when the test was done.


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CherylS Apprentice

It is my understanding that the biopsy is the gold standard and if shows celiac disease, you have it.  I suggest you get a second opinion, ask for copies of your biopsy report and labs and find a GI doctor who knows about celiac disease.

Binti1962 Rookie

Thanks for the reply CherylS.  I appreciate your feedback, because I was thinking along those same lines.

manasota Explorer

Binti,

The U. of chicago Celiac website states they recommend 12 weeks of gluten ingestion prior to blood testing and 2 weeks of gluten prior to the biopsy.  It sounds like you didn't have a long enough exposure to gluten prior to the blood tests.

The biopsy results alone are not sufficient for a Celiac diagnosis.

 

 

squirmingitch Veteran

Hi Binti, 

This is not your exact case but close enough:

Open Original Shared Link

 

Binti1962 Rookie

Thanks for the info and replies!  I didn't know that the biopsy results alone weren't sufficient for a diagnosis.  Perhaps somethine else is causing the villi damage.  I will keep eating gluten and maybe have the blood test repeated in 12 weeks

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
    • Seaperky
      I found at Disney springs and Disney they have specialist that when told about dietary restrictions they come and talk to you ,explain cross contamination measures tsken and work with you on choices. Its the one place I dont worry once I've explained I have celiac disease.  Thier gluten free options are awesome.
    • Churley
      Have you tried Pure Encapsulations supplements? This is a brand my doctor recommends for me. I have no issues with this brand.
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