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Is Effective Enzyme Therapy for Celiac Disease Just Around The Corner?


Scott Adams

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Scott Adams Grand Master
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Enzyme Latiglutenase improves symptoms in some celiac patients, but which ones? Enzymes have shown some promise for treating celiac symptoms, but so far none has to improve histology or symptoms in celiac patients.

There are currently several efforts underway to develop successful commercial enzyme treatments for celiac disease. Efforts include looking at the digestive enzymes in plants, such as the papaya and star fruits, including such predatory plants, such as the pitcher plant.

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Victoria1234 Experienced

Shouldn't they be studying why celiacs who have been gluten-free for a year are still seropositive and having moderate to severe symptoms? 

It sounded like the pill was suppposed to be taken with meals that might have cc ? So why would they do a study where it's given with gluten-free meals? What would it be breaking down if the meal has no gluten? How would it help? I'm confused. But it's been a long day.

update

Just read some drug company is going to be selling these pills in 2023. I hope by then the poor celiacs still having bad problems are able to figure out why they are still hurting instead of having to take super expensive pills.

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    • trents
      Yes, some people do get withdrawal from gluten but gluten withdrawal doesn't usually cause gut pain. Maybe more like general body aches and discomfort. We have articles on gluten withdrawal on this forum. You might do a search for them. Applesauce is very acidic and some brands have added vitamin C (ascorbic acid) which makes them more acidic. This can damage the stomach lining if you eat it too often. Especially if your stomach lining is already compromised. Ibuprofen inhibits the body's ability to rebuild the stomach's protective mucosal lining. That's why it can cause peptic ulcers. As strange as it may sound, low level irritation/inflammation stimulates the body to rebuild the stomach lining. There are two steps in this rebuilding process known as COX 1 and COX 2. Ibuprofen represses both COX 1 and COX 2. Celecoxcib, a prescription anti inflammatory, inhibits only COX 2, making it less likely to cause damage to the gut lining.
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      Do you or anyone know alot about ibuprofen  I wasn't sure if I was eating too much apple sauce.   Something is making my pain so much worse  I'm referring to the intense pins and needles in my feet and lower legs.  Jaw actually has tardive dystonia and muscle spasms throughout my back Almost like an opposite effect that a pain reliever would do. I'm fairly new to this. Whatever is going on seems to be worsening  Do people get a withdrawal effect from gluten?  It's extremely painful 😖  I'll post that question or research on the site  Thank you everyone for responding 
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