Confused about celiac test results

[Ays16]

Hi i recently got tested for celiac after continuous digestive issues since I was 15. My crp has been elevated but lupus and other autoimmune problems have been ruled out. Negative Ana. My rheumatologist recently did a celiac panel but I am confused by the results? Does this indicate celiac? 

The results are 

Glidian igg 5 (<20) 

glidian iga 38H (>20) 

Ttg iga 20 H (>20)

Ttg igg 8 (<20) 

thanks so much in advance! 

[squirmingitch]

You have 2 positives. Yes, it indicates celiac. The next step is an endoscopic biopsy. Be sure to keep eating gluten each & every day until the biopsy is over with. 

[Ays16]

Thanks so much! I wasn’t sure if they all had to be postive or if there was a difference as to why I am High IGA but not IGG. 

[squirmingitch]

You're welcome. Actually there are 6 tests in the full panel but that is neither here nor there now that you've turned up positive on 2 of the 4 you were given. It only takes 1 positive to trigger moving to the endoscopic biopsy. I don't think I've ever seen anyone be positive on all the tests across the board. I'm not even sure that's possible but logic tells me it has to be possible. They are just different tests --- some people test positive on the IGG and some test positive on the IGA. 

I am going to repeat this again b/c so many people get told by their docs that they can quit eating gluten now. Do not believe them!!!! You must keep eating gluten each day okay? Otherwise you are almost sure to have false negative biopsies. You don't have to eat a lot. Just a slice of bread or a couple crackers will do it. 

[Ays16]

Thank you!!! 

[squirmingitch]

You're most welcome. Let us know how things go along okay? 

Also, you might want to start getting prepped for going gluten free. Start learning now so it isn't so overwhelming later. Here's a link to the Newbie 101:

 

[tessa25]

On 1/15/2018 at 8:11 PM, squirmingitch said:

I don't think I've ever seen anyone be positive on all the tests across the board. I'm not even sure that's possible but logic tells me it has to be possible.

Raises hand.

[squirmingitch]

11 hours ago, tessa25 said:

Raises hand.

Ok tessa! Point taken and I will remember that too. 

[Gemini]

On 1/15/2018 at 10:11 PM, squirmingitch said:

You're welcome. Actually there are 6 tests in the full panel but that is neither here nor there now that you've turned up positive on 2 of the 4 you were given. It only takes 1 positive to trigger moving to the endoscopic biopsy. I don't think I've ever seen anyone be positive on all the tests across the board. I'm not even sure that's possible but logic tells me it has to be possible. They are just different tests --- some people test positive on the IGG and some test positive on the IGA. 

I am going to repeat this again b/c so many people get told by their docs that they can quit eating gluten now. Do not believe them!!!! You must keep eating gluten each day okay? Otherwise you are almost sure to have false negative biopsies. You don't have to eat a lot. Just a slice of bread or a couple crackers will do it. 

I am one of those people who tested high positive on every test on the panel and I had a complete panel done.  But I had a lifetime of symptoms and wasn't diagnosed until I was 46 so that's a lot of damage.  This is why I did not need the biopsy for a diagnosis.  It really doesn't matter because, like you stated, with 2 positives on the IgA, there is a high probability of Celiac.  A biopsy would be indicated with those results.  It would have been nice if they had run the EMA, though.

[Ays16]

Thanks guys! I have an endoscopy/colonoscopy  feb 5th, so we will see. I have had digestive issues for the past like 10 years. GERD, migraines, lactose intolerant, dizziness on and off starting last year. My test just always show chronic inflammation, I thought they tested for celiac last time but it was only H. pylori samples. As much as I don’t want to have celiac I’m hoping this could be the root of my problem! My doctor said I should probably go gluten free after the test regardless of the results. You guys have been so helpful!!