Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

What do these mean?!

TWilson9608
 Share

Recommended Posts

TWilson9608 Newbie
TWilson9608
Posted

Hello. My youngest daughter (8 y/o) was recently diagnosed with Celiac Disease, thorough labs and biopsies. It was suggested that our who family be tested and so I immediately began that process. My middle daughter (15 y/o) labs came in with a positive IGA of 13 but the transgluten was negative. What could this mean? My middle daughter is being referred to the pros GI specialist that my youngest goes to but her pediatric doctor is running a great deal more labs to look into other autoimmune disorders as well. I am being told, regardless of the negative portion that she does have Celiacs and obviously they'll need to confirm with biopsies, but both the labs and the pediatrician say its celiac...Can anyone clarify this more for me because I can't seem to find the correct search online to find the answers that I am looking for and my anxiety is through the roof right now! TIA

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


cyclinglady Grand Master
cyclinglady
Posted
8 minutes ago, TWilson9608 said:

Hello. My youngest daughter (8 y/o) was recently diagnosed with Celiac Disease, thorough labs and biopsies. It was suggested that our who family be tested and so I immediately began that process. My middle daughter (15 y/o) labs came in with a positive IGA of 13 but the transgluten was negative. What could this mean? My middle daughter is being referred to the pros GI specialist that my youngest goes to but her pediatric doctor is running a great deal more labs to look into other autoimmune disorders as well. I am being told, regardless of the negative portion that she does have Celiacs and obviously they'll need to confirm with biopsies, but both the labs and the pediatrician say its celiac...Can anyone clarify this more for me because I can't seem to find the correct search online to find the answers that I am looking for and my anxiety is through the roof right now! TIA

Which IgA was it (and the lab range)?

  • Anti-tissue transglutaminase (tTG)
  • Anti-endomysium (EMA)
  • Anti-deamidated gliadin peptides (DGP)

It only takes one positive on any of these three tests to further investigate (e.g. biopsies via endoscopy).  

TWilson9608 Newbie
TWilson9608
Posted
  • Author
(edited)

Celiac IGA Gliadian Deamidatedb13

IGA Transglutamainase 0.3

Edited by TWilson9608
cyclinglady Grand Master
cyclinglady
Posted

Okay, the information based on what you provided earlier (13 positive) seems to indicate that she needs to be elevated by a Gastroenterologist.  She has a positive on the DGP IgA, which is like me.  I have never had a positive on the EMA or the TTG even in follow up testing. The celiac tests are not perfect.  It is one reason why there are several.  Do not let your screening doctor (maybe your PED) tell you that she is not positive because she did not get a positive on the TTG.  

  It is a lot to take in, but knowing a diagnosis is so important.  Hang in there.  I get it.  I have a daughter too!  

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      129,678
    • Most Online (within 30 mins)
      7,748
    Celiac79
    Newest Member
    Celiac79
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.2k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Mari
      Cruise and GliadinX

      By Mari · Posted

      Hi StevieP I think it is best to take GliadinX Just before, during or just after you eat a food that may have a small amount of gluten.  Taking 2 capsules of GliadinX in the morning will not protect you all day because it will be long gone when you need it. The upper digestive system is where the digestive enzymes break down gluten. The problem with Celiacs is that normal digestion will only break down gluten to the point where the small fragments will still cause a reaction. GliadinX will break down the fragments so that they are too small to start the autoimmune reaction.  The label on my bottle reads'it works in the stomach' and that is ver concentrated so 1 capsule is the recomm Hope this helps/Have a lovely cruise.ended dose for each meal. 
    • StevieP.
      Cruise and GliadinX

      By StevieP. · Posted

      Thanks so much for that information!! That helps me out alot!!
    • Scott Adams
      Help needed

      By Scott Adams · Posted

      It’s completely understandable to feel confused and anxious—colonoscopy prep can feel overwhelming, especially when you’re already dealing with symptoms like loose stools and elevated inflammation markers (that high calprotectin and CRP definitely warrant further investigation!). Regarding the senna tablets: The warning about avoiding senna with IBD (like Crohn’s or colitis) is typically because it can irritate an already inflamed colon. Since you don’t yet have a confirmed diagnosis—but your brother has colitis—it might be worth calling your gastroenterologist’s office today to clarify if you should skip the senna given your symptoms and family history. Some clinics have an on-call nurse who can advise quickly. For the prep itself: Plenvu is strong, so if your bowels are already loose, the senna might be overkill. Stick to clear liquids tomorrow (broth, apple juice, etc.) and stay near a bathroom! For anxiety, remember the procedure itself is painless (you’ll likely be sedated), and the prep is the hardest part. Bring a phone charger or book to the clinic, and treat yourself afterward to something gentle on your stomach (like mashed potatoes or yogurt). Hang in there—this is a big step toward answers. You’re doing great advocating for yourself!
    • Scott Adams
      Wheat Straw Dishes

      By Scott Adams · Posted

      Great question! Wheat straw dishes are typically made from the stalks of wheat plants (which are naturally gluten-free) combined with a binding resin. While the straw itself shouldn’t contain gluten, the safety depends on how the product is processed. Some manufacturers may use wheat-based binders or process the straw in facilities that handle gluten, creating cross-contact risks. To be safe, I’d recommend reaching out to the company directly to ask: 1) If their wheat straw material is tested to confirm it’s free of gluten proteins, and 2) Whether the production line avoids cross-contamination with gluten-containing ingredients. Many brands now cater to gluten-free consumers and will provide detailed answers. If you’re uncomfortable with the uncertainty, alternatives like bamboo, ceramic, or glass dishes are inherently gluten-free and worry-free. Always better to double-check—your diligence is totally justified!
    • Scott Adams
      Lost

      By Scott Adams · Posted

      I’m so sorry you’ve been struggling for so long without the answers or relief you deserve. It’s incredibly frustrating to have a celiac diagnosis yet still face debilitating symptoms, especially after decades of strict gluten-free living. Your history of chronic health issues—SIBO, food allergies, recurrent infections, and now potential complications like nerve pain (left leg) and mucosal ulcers—suggests there may be overlapping conditions at play, such as autoimmune comorbidities (e.g., Hashimoto’s, Sjögren’s), nutrient deficiencies, or even refractory celiac disease (though rare). Stanford is an excellent step forward, as their specialists may uncover missed connections. The medical gaslighting you’ve endured is unacceptable, and while legal action is an option, focusing on thorough testing (e.g., repeat endoscopy, micronutrient panels, autoimmune markers, skin biopsy for dermatitis herpetiformis) might be more immediately helpful. Menopause can absolutely exacerbate underlying inflammation, so hormonal imbalances should also be explored. For symptom relief, some in the celiac community find low-dose naltrexone (LDN) or mast cell stabilizers helpful for systemic issues, but a functional medicine doctor (if accessible) could tailor supplements to your needs. You’re not alone in this fight—keep advocating fiercely at Stanford. Document everything meticulously; it strengthens both medical and potential disability claims. Sending you strength—this shouldn’t be so hard, and you deserve real solutions.
×
×
  • Create New...