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Why Does Gluten Make Me So Sick So Quickly?

Ginger38
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Ginger38 Rising Star
Ginger38
Posted

I’m just wondering why once you’ve eliminated gluten and started the healing process, that if you get glutened or consume gluten somehow people get so sick so quick? Does the inflammation or immune reaction not have to build up over time or is it just instant reaction anytime any trace of gluten is ingested?
I’ve noticed my reactions seem to be much stronger now and not just GI issues.. my whole body aches, I feel like I have the flu, brain fog is bad, my depression and anxiety get really bad and the fatigue is absolutely debilitating. And it doesn’t just last for a few days… it seems to progressively get worse and lasts for a while. Is all this normal? 

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Scott Adams Grand Master
Scott Adams
Posted

I think this can vary quite a lot from person to person. Many people seem to get more sensitive to gluten after they have eliminated it for a few weeks or more, and it sounds like you are in this group. 

After I was gluten-free for a couple of years I recall being less sensitive to it, and I would not notice any reaction to small amounts of accidental gluten. For me this has changed over time, and now I do have stronger reactions if I get any gluten, but I would not call them severe reactions.

RMJ Mentor
RMJ
Posted

The rapid reaction is due to cytokine release:

Cytokine release in response to gluten challenge

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