Do these results means Celiac positive?

[Bonnie Oxford]

My daughter got her test results today frustratingly via a portal with no explanation.  The Doctor's appointment is a few days away.  

Results:          Deamidated Gliadin Abs, IgA            10
                      Deamidated Gliadin Abs, IgG             63
                      t-Transglutaminase (tTG) IgA                7
                      t-Transglutaminase (tTG) IgG                5
                      Endomysial Antibody IgA               Positive Abnormal
                      Immunoglobulin A, Qn, Serum           116

 

Does this mean she is positive for Celiac?

                    

              

 

                      

[knitty kitty]

Could you please post the reference ranges of these tests?  

Tests from different labs use different reference ranges, so we don't know if your daughter's ranges are high or low.

Thanks!

[trents]

Welcome to the forum, Bonnie!

Did the report include ranges for what is normal? Different labs use different testing concoctions and therefore the ranges are not standard values. So, cant tell much from what you posted except for the EMA which is stated to be positive and abnormal. The EMA is very specific for celiac disease and the chances of a positive in that one being caused by something else is slim.

Edited July 26, 2023 by trents

[Bonnie Oxford]

Deamidated Gliadin Absm IgA      10            0-19 negative
                                                                      20-30  weak positive
                                                                       >30 Moderate to strong

Deamidated Gliadin Absm IgG       63          0-19 negative
                                                                     20-30  weak positive
                                                                      >30 strong positive

t-Translutaminase (tTG) IgA             7            0-3 Negative
                                                                       4-10 weak positive
                                                                       >10 positive
 

t-Translutaminase (tTG) IgG           5             0-5 Negative
                                                                      6-9 Weak Positive
                                                                       >9 Positive

Endomysial Antibody IgA           Positive Abnormal                                 Negative
immunoglobulin A, Qn, Serum              116                     mg/dL                 87-352

     

 

 

[RMJ]

Your daughter has three positive tests for celiac disease, out of five.  One does NOT need to have all of the tests positive to have celiac disease, some patients only have one positive.  The next step may be an endoscopy.  Be sure to have her continue eating gluten until all testing is complete.

[Bonnie Oxford]

Shocking!  But thank you for the information.

[trents]

40 minutes ago, Bonnie Oxford said:

Shocking!  But thank you for the information.

Why do you say that, Bonnie?

[Bonnie Oxford]

Why am I shocked?  Because she is 28 years old and we had been told she had PCOS.  We never saw Celiacs coming.  It is just a shocking diagnosis.   The gastroenterologist had diagnosed her the IBS, but decided to do the Celiacs test even though she thought it was a long shot.  A lot of things make sense now, but it is still shocking!

[trents]

Life is full of surprises, isn't it? This will mean a major change in her life and require a lot of adjustments for family and friends in order to keep her safe when eating. The social impact is the hardest thing for many to deal with. So much of our socialization revolves around food. Some will not understand. But it becomes the new norm with time.

[Bonnie Oxford]

Yes it will!  Fortunately, she is a super adventurous eater and not picky.   It is going to be a learning curve for all of us.  Thanks to all of you that have responded.

[trents]

Keep us posted with regard to an endoscopy/biopsy. As RMJ indicated, normally, this is done to confirm the results of the antibody testing. She should not start cutting back on gluten until that is done, if it is to be called for.

[knitty kitty]

@Bonnie Oxford,

This article might be of interest.  It explains the importance of vitamins in PCOS.  Nutritional deficiencies are common in newly diagnosed Celiacs.  

A Properly Balanced Reduction Diet and/or Supplementation Solve the Problem with the Deficiency of These Vitamins Soluble in Water in Patients with PCOS

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996738/

This study recommends Benfotiamine Vitamin B 1 as well as Folate B9 and Cobalamine B12, in addition to others, to correct nutritional deficiencies found in PCOS.

Best wishes!  

[Bonnie Oxford]

Thank you guys for being so welcoming and informative!  I really appreciate it.

[Guest Neerajkirola]

17 hours ago, Bonnie Oxford said:

My daughter got her test results today frustratingly via a portal with no explanation.  The Doctor's appointment is a few days away.  

Results:          Deamidated Gliadin Abs, IgA            10
                      Deamidated Gliadin Abs, IgG             63
                      t-Transglutaminase (tTG) IgA                7
                      t-Transglutaminase (tTG) IgG                5
                      Endomysial Antibody IgA               Positive Abnormal
                      Immunoglobulin A, Qn, Serum           116

 

Does this mean she is positive for Celiac?

                    

              

 

                      

I am not a medical professional, but I can try to provide some general information based on the test results you've shared. However, it's important to remember that only a qualified healthcare professional can interpret these results accurately and provide a diagnosis. If you have concerns about your daughter's health, it's best to wait for the doctor's appointment for a proper explanation and guidance.

From the test results you provided, it seems that some of the values are within the normal range, but a few are abnormal. The positive results for Endomysial Antibody IgA could indicate celiac disease, but a definitive diagnosis would require further evaluation and additional tests.

Celiac disease is typically diagnosed through a combination of blood tests and an intestinal biopsy. The doctor will consider the overall clinical picture, medical history, and other factors to arrive at a conclusive diagnosis.

Please consult your daughter's healthcare provider for a thorough explanation of the results and appropriate guidance based on her health situation. They can provide the best advice and recommendations for her care.

 

Thanks

[Bonnie Oxford]

Thank you so much for replying.  Her followup is in a few days.

[Scott Adams]

This article has some detailed information on how to be 100% gluten-free, so it may be helpful:

 

 

[Bonnie Oxford]

My head is spinning and so is hers.  You guys have been so helpful and informative.  I cannot thank you enough.

[silverbirchu2]

1 hour ago, Bonnie Oxford said:

Thank you so much for replying.  Her followup is in a few days.

Don't worry 👍  luck x