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Why Can't We Get Rid Of Autoimmune Diseases?


chrissy

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chrissy Collaborator

if something happens to "turn on" celiac disease and other autoimmune diseases------why can't we turn them back off? it just seems that if our bodies are so good (ideally) at healing themselves we should be able to heal from an autoimmune disease. i know that MS can go into remission because my grandfather had it and his went into remission. lupus can also do that and probably others as well, but not celiac or diabetes. my sister has an autoimmune disease called primary schlerosing cholingitis and it will eventually destroy her liver and she will need a transplant----if one of the other problems connected with her disease doesn't kill her. i just keep thinking that if something starts these things, something should be able to stop them.


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Jestgar Rising Star

You can stop Celiac damage by not eating gluten. If we knew what caused or limited the other diseases we could stop those too. Does MS spontaneously go into remission, or do we unknowingly change something that no longer activates it? If you moved to a small island that had only fish and local fruits to eat wouldn't your Celiac be in remission even though you weren't consciously doing anything to change it?

Nantzie Collaborator

No answers, but I've wondered about this too. Maybe it's just something science hasn't figured yet.

Nancy

mommida Enthusiast

Wouldn't we have to have doctors to correctly diagnose celiac disease first?

L.

Nantzie Collaborator
Wouldn't we have to have doctors to correctly diagnose celiac disease first?

L.

ROFLMAO!!!

:lol::lol::lol:

Nancy

lorka150 Collaborator
if something happens to "turn on" celiac disease and other autoimmune diseases------why can't we turn them back off? it just seems that if our bodies are so good (ideally) at healing themselves we should be able to heal from an autoimmune disease. i know that MS can go into remission because my grandfather had it and his went into remission. lupus can also do that and probably others as well, but not celiac or diabetes. my sister has an autoimmune disease called primary schlerosing cholingitis and it will eventually destroy her liver and she will need a transplant----if one of the other problems connected with her disease doesn't kill her. i just keep thinking that if something starts these things, something should be able to stop them.

There are four types of MS: one is Relapsing Remitting, and there are periods where you have attacks, 'heal', and then the process goes on again. After having that for awhile (the timeline is at about 30 years right now), it often changes to Progressive, and speeds downhill.

2kids4me Contributor
if something happens to "turn on" celiac disease and other autoimmune diseases------why can't we turn them back off? it just seems that if our bodies are so good (ideally) at healing themselves we should be able to heal from an autoimmune disease.

Most of the problem is that researchers know that immune disease is caused by the body making antibodies to "self" something it doesnt normallly do. They havent found the "on button" much less who/what is sneaking in and flipppin the darn switch :huh:

When they find the on button, then they have to find the off switch, no doubt hidden better than the on button :o

There are some diseases that seem to have a dimmer switch (like relapsing remitting forms of immune illness)..and someone keeps playing with the switch there ......

Top it off with - there are over 60 autoimmune diseases - each with different underlying genetic flaws at diiferent points on chromosomes AND some poeple with these "flaws" dont ever develop the disease while others will... that elusive trigger again.

The system that's involved in healing the body is also the system that is behind the immune mediated diseases. :o


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Helena Contributor

Interesting question. I don't know, but I would guess that it is the same reason why for instance if we have chicken pox once we generally won't get it again. Once the immune system recognizes something as pathogenic, it continues to do so.

flagbabyds Collaborator

Some people say that it goes into remission when you are in need to reproduce in your teens and early twenties but then it comes back, all this time you have the disease and it is diong damage to your intestines but your body does not show symptoms,

not sure if this is true, but i feel no incline to test it, i am 16 now and i still get symptoms and such.

that's all i have ever heard about it.

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      Welcome to the forum, @McKinleyWY, For a genetic test, you don't have to eat gluten, but this will only show if you have the genes necessary for the development of Celiac disease.  It will not show if you have active Celiac disease.   Eating gluten stimulates the production of antibodies against gluten which mistakenly attack our own bodies.  The antibodies are produced in the small intestines.  Three grams of gluten are enough to make you feel sick and ramp up anti-gluten antibody production and inflammation for two years afterwards.  However, TEN grams of gluten or more per day for two weeks is required to stimulate anti-gluten antibodies' production enough so that the anti-gluten antibodies move out of the intestines and into the bloodstream where they can be measured in blood tests.  This level of anti-gluten antibodies also causes measurable damage to the lining of the intestines as seen on biopsy samples taken during an endoscopy (the "gold standard" of Celiac diagnosis).   Since you have been experimenting with whole wheat bread in the past year or so, possibly getting cross contaminated in a mixed household, and your immune system is still so sensitized to gluten consumption, you may want to go ahead with the gluten challenge.   It can take two years absolutely gluten free for the immune system to quit reacting to gluten exposure.   Avoiding gluten most if the time, but then experimenting with whole wheat bread is a great way to keep your body in a state of inflammation and illness.  A diagnosis would help you stop playing Russian roulette with your and your children's health.      
    • trents
      Welcome to the celiac.com community, @McKinleyWY! There currently is no testing for celiac disease that does not require you to have been consuming generous amounts of gluten (at least 10g daily, about the amount in 4-6 slices of wheat bread) for at least two weeks and, to be certain of accurate testing, longer than that. This applies to both phases of testing, the blood antibody tests and the endoscopy with biopsy.  There is the option of genetic testing to see if you have one or both of the two genes known to provide the potential to develop celiac disease. It is not really a diagnostic measure, however, as 30-40% of the general population has one or both of these genes whereas only about 1% of the general population actually develops celiac disease. But genetic testing is valuable as a rule out measure. If you don't have either of the genes, it is highly unlikely that you can have celiac disease. Having said all that, even if you don't have celiac disease you can have NCGS (Non Celiac Gluten Sensitivity) which shares many of the same symptoms as celiac disease but does not involve and autoimmune reaction that damages the lining of the small bowel as does celiac disease. Both conditions call for the complete elimination of gluten from the diet. I hope this brings some clarity to your questions.
    • McKinleyWY
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      Okay went online to check green mountain k cups .It was said that the regular coffees are fine but they couldn’t guarantee cross contamination.with the flavors. im trying to figure out since I eliminated the suyrup so far so good. I’m hoping. thanks it feels good to listen to other people there views.
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