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Why Can't We Get Rid Of Autoimmune Diseases?


chrissy

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chrissy Collaborator

if something happens to "turn on" celiac disease and other autoimmune diseases------why can't we turn them back off? it just seems that if our bodies are so good (ideally) at healing themselves we should be able to heal from an autoimmune disease. i know that MS can go into remission because my grandfather had it and his went into remission. lupus can also do that and probably others as well, but not celiac or diabetes. my sister has an autoimmune disease called primary schlerosing cholingitis and it will eventually destroy her liver and she will need a transplant----if one of the other problems connected with her disease doesn't kill her. i just keep thinking that if something starts these things, something should be able to stop them.


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Jestgar Rising Star

You can stop Celiac damage by not eating gluten. If we knew what caused or limited the other diseases we could stop those too. Does MS spontaneously go into remission, or do we unknowingly change something that no longer activates it? If you moved to a small island that had only fish and local fruits to eat wouldn't your Celiac be in remission even though you weren't consciously doing anything to change it?

Nantzie Collaborator

No answers, but I've wondered about this too. Maybe it's just something science hasn't figured yet.

Nancy

mommida Enthusiast

Wouldn't we have to have doctors to correctly diagnose celiac disease first?

L.

Nantzie Collaborator
Wouldn't we have to have doctors to correctly diagnose celiac disease first?

L.

ROFLMAO!!!

:lol::lol::lol:

Nancy

lorka150 Collaborator
if something happens to "turn on" celiac disease and other autoimmune diseases------why can't we turn them back off? it just seems that if our bodies are so good (ideally) at healing themselves we should be able to heal from an autoimmune disease. i know that MS can go into remission because my grandfather had it and his went into remission. lupus can also do that and probably others as well, but not celiac or diabetes. my sister has an autoimmune disease called primary schlerosing cholingitis and it will eventually destroy her liver and she will need a transplant----if one of the other problems connected with her disease doesn't kill her. i just keep thinking that if something starts these things, something should be able to stop them.

There are four types of MS: one is Relapsing Remitting, and there are periods where you have attacks, 'heal', and then the process goes on again. After having that for awhile (the timeline is at about 30 years right now), it often changes to Progressive, and speeds downhill.

2kids4me Contributor
if something happens to "turn on" celiac disease and other autoimmune diseases------why can't we turn them back off? it just seems that if our bodies are so good (ideally) at healing themselves we should be able to heal from an autoimmune disease.

Most of the problem is that researchers know that immune disease is caused by the body making antibodies to "self" something it doesnt normallly do. They havent found the "on button" much less who/what is sneaking in and flipppin the darn switch :huh:

When they find the on button, then they have to find the off switch, no doubt hidden better than the on button :o

There are some diseases that seem to have a dimmer switch (like relapsing remitting forms of immune illness)..and someone keeps playing with the switch there ......

Top it off with - there are over 60 autoimmune diseases - each with different underlying genetic flaws at diiferent points on chromosomes AND some poeple with these "flaws" dont ever develop the disease while others will... that elusive trigger again.

The system that's involved in healing the body is also the system that is behind the immune mediated diseases. :o


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Helena Contributor

Interesting question. I don't know, but I would guess that it is the same reason why for instance if we have chicken pox once we generally won't get it again. Once the immune system recognizes something as pathogenic, it continues to do so.

flagbabyds Collaborator

Some people say that it goes into remission when you are in need to reproduce in your teens and early twenties but then it comes back, all this time you have the disease and it is diong damage to your intestines but your body does not show symptoms,

not sure if this is true, but i feel no incline to test it, i am 16 now and i still get symptoms and such.

that's all i have ever heard about it.

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    • knitty kitty
      So you're saying that you think you should have severe intestinal damage since you've had the symptoms so long?   DGP IgG antibodies are produced in response to a partial gluten molecule.  This is different than what tissue transglutaminase antibodies are  produced in response to.   TTg IgA antibodies are produced in the intestines in response to gluten.  The tTg IgA antibodies attack our own cells because a structural component in our cell membranes resembles a part of gluten.  There's a correlation between the level of intestinal damage with the level of tTg antibodies produced.  You are not producing a high number of tTg IgA antibodies, so your level of tissue damage in your intestines is not very bad.  Be thankful.   There may be reasons why you are not producing a high quantity of tTg IgA antibodies.  Consuming ten grams or more of gluten a day for two weeks to two months before blood tests are done is required to get sufficient antibody production and damage to the intestines.  Some undiagnosed people tend to subconsciously avoid lots of gluten.  Cookies and cakes do not contain as much gluten as artisan breads and thick chewy pizza crust.  Anemia, diabetes and thiamine deficiency can affect IgA antibody production as well.   Do you carry genes for Celiac?  They frequently go along with EDS.
    • rei.b
      I was tested for celiac at the same time, so I wasn't taking naltrexone yet. I say that, because I don't. The endoscopy showed some mild inflammation but was inconclusive as to celiac disease. They took several biopsies and that's all that was shown. I was not given a Marsh score.
    • knitty kitty
      Food and environmental allergies involve IgE antibodies.  IgE antibodies provoke histamine release from mast cells.   Celiac disease is not always visible to the naked eye during endoscopy.  Much of the damage is microscopic and patchy or out of reach of the scope.  Did they take any biopsies of your small intestine for a pathologist to examine?  Were you given a Marsh score? Why do you say you "don't have intestinal damage to correlate with lifelong undiagnosed celiac disease"?   Just curious.  
    • rei.b
      I was tested for food allergies and environmental allergies about 7 months before I started taking Naltrexone, so I don't think that is the cause for me, but that's interesting!  The main thing with the celiac thing that is throwing me off is these symptoms are lifelong, but I don't have intestinal damage to correlate with lifelong undiagnosed celiac disease.
    • trents
      Welcome to the forum, @Kara S! Warrior bread is a grain free bread product. Google it. There are commercial mixes available, I believe, Youtube videos and many recipes. 
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