Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Carry The Gene Dq2.5 And Eating Gluten

karliemma

Recommended Posts

karliemma Newbie
karliemma
Posted

Hi, I don't have coeliac disease but i found out i carry one of the main genes for it, DQ2.5. I was just wondering if anyone knew if it's ok to keep eating gluten or will it increase my chances of developing coeliac disease? I also have fructose malabsorption, so i'm not eating that much gluten anyway because i can't eat wheat, however i still eat things with wheat/gluten in them. Do you think its ok to continue doing so? Thanks

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


lizard00 Enthusiast
lizard00
Posted

Welcome to the Board!!!

That's quite a controversial question...

Yes, having the gene does increase your risk of Celiac. And one of the criteria for developing Celiac is that you must be currently eating gluten... But as you already know, doesn't mean that you will have it. There are many folks that will tell you that if you have the gene, your best bet is to eliminate all possibilities and go gluten-free. Others will say that if you can eat it, go for it. It's really your choice to make, although my personal opinion would be to avoid gluten. Do you know for sure that you don't have Celiac? It is possible to have it and have no symptoms. Did your doctor advise you to avoid it or not?

karliemma Newbie
karliemma
Posted
  • Author
Welcome to the Board!!!

That's quite a controversial question...

Yes, having the gene does increase your risk of Celiac. And one of the criteria for developing Celiac is that you must be currently eating gluten... But as you already know, doesn't mean that you will have it. There are many folks that will tell you that if you have the gene, your best bet is to eliminate all possibilities and go gluten-free. Others will say that if you can eat it, go for it. It's really your choice to make, although my personal opinion would be to avoid gluten. Do you know for sure that you don't have Celiac? It is possible to have it and have no symptoms. Did your doctor advise you to avoid it or not?

well i had the antibody tests done a few months ago before i found out i had the gene and they were negative. although i had been wheat free for awhile i was not gluten free, and i made sure i ate gluten and wheat containing foods for about 2 weeks before i got tested. i don't know however if i was really eating enough of it though to make a difference. my iron levels were fine too. however my stomach symptoms kept getting worse but i think that could be put down to the fructose malabsorption problem. i went to see a gastroenterologist and he ordered the gene test for me. i asked my doctor if i have to avoid gluten forever and she said i'd like to say no but there is no point in waiting for it happen (as in celiac disease to happen). so she seems to think i should avoid it, however the gastro man didn't really go into it. i had another blood test done for IgE or the tissutransglutaminase one, and apparantly my levels were up a bit, which the doctor said means i'm reacting to something but they don't know what because it takes some time to show up? i don't even know what that test was for though anyway, what does it test for? she reckons it has something to do with having the celiac gene. i'm going back to the gastroenterologist at the end of april so maybe he can explain it in more detail to me? what's your opinion?

happygirl Collaborator
happygirl
Posted

In America, 1 in 133 Americans has Celiac (slightly less than 1%).

However, 30-40% of the American population has either HLA DQ2 or HLA DQ8.

So, just having the gene doesn't necessarily mean that you will get Celiac. The vast majority don't.

However, if you are having symptoms, and have had other tests run to determine if you have any other conditions that could be causing your symptoms, then I don't see any harm in trying a gluten free diet (gluten free, not gluten lite!). You may not have Celiac, but for reasons unknown, you may have problems with gluten.

You may want to get a copy of your bloodwork so that you can see the results of the bloodwork yourself.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,350
    • Most Online (within 30 mins)
      7,748
    Bea71
    Newest Member
    Bea71
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • par18
      Is it gluten?

      By par18 · Posted

      Thanks for the reply. 
    • Scott Adams
      nothing has changed

      By Scott Adams · Posted

      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Is it gluten?

      By Scott Adams · Posted

      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
    • Seaperky
      Trip to Anaheim/Disney

      By Seaperky · Posted

      I found at Disney springs and Disney they have specialist that when told about dietary restrictions they come and talk to you ,explain cross contamination measures tsken and work with you on choices. Its the one place I dont worry once I've explained I have celiac disease.  Thier gluten free options are awesome.
    • Churley
      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      By Churley · Posted

      Have you tried Pure Encapsulations supplements? This is a brand my doctor recommends for me. I have no issues with this brand.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.