Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):
  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Very Interesting Article


SD77

Recommended Posts

SD77 Newbie

I've been trying to research epigenetics and Celiac (I'm sure there's a link, and it would explain why genetics test don't predict Celiac Disease too well), and this was the closest thing I found; It is a very interesting way to look at wheat in the human diet, and discusses the 'Celiac Iceberg'...why some people have it and don't know, why some people think they have it but can't get a positive diagnosis, etc.

I don't know if this link will post correctly...but it's worth a try!!

Open Original Shared Link


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



SD77 Newbie

Oh, and if anyone knows of any articles regarding epigenetics and celiac disease, let me know!!

Thanks!

ranger Enthusiast

Interesting article. Suddenly, I feel "lucky"! Thanks for posting this

Susan

Crimson Rookie

That is a damn fine article! I like the way this was written to show how our bodies are having a HEALTHY response to an UNHEALTHY food! Grand!

ravenwoodglass Mentor

Great article, thanks for posting this.

mushroom Proficient

This was the most interesting and informative article I have ever read on the effects of wheat and its various amino acid chains and peptides on our bodies. It really does make one wonder if the FDA does not have tongue in cheek (or hand in national pocket) when recommending wheat consumption by the general populace. When I consider my religious adherence to whole wheat bread, to wheat germ, to wheat-based cereals, it really makes me cringe what I was doing to my body. And my mother's insistence on the eating of Vimax (hot wheat cereal),Weetbix, and all the other things that used to give me tummy aches at school. I was telling her even back then, but to no avail--"Eat it, it's good for you!" Ha! :rolleyes:

q

Roda Rising Star

That was a good article. I feel my pcp, whom I have only seen once since Dec. 2006 and after 10 months diagnosed, would not buy into it. Probably not all his fault, its just that for generations people have been told that it is good for you. Hopefully articles and more studies like this will change the way we (as a population) view what we eat. I definately think twice about the food I consume now.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



codetalker Contributor

Many thanks for posting the link to the article. It contains an interesting and valuable perspective.

One question for general response:

At the end of the article (the paragraph immediately preceding the conclusion), glutamic acid is mentioned in a negative light. How does that correlate to L-glutamine which has been put forward by some as something that may promote intestinal healing?

A quick search found an article that described glutamine as an amide of glutamic acid. I found a definition of an amide but it is over my head.

Thanks again.

mushroom Proficient
At the end of the article (the paragraph immediately preceding the conclusion), glutamic acid is mentioned in a negative light. How does that correlate to L-glutamine which has been put forward by some as something that may promote intestinal healing?

A quick search found an article that described glutamine as an amide of glutamic acid. I found a definition of an amide but it is over my head.

That part about glutamic acid set off some alarm bells in my head too. For some reason I did not take the L-glutamine my ND recommended. Maybe it's just as well??? :huh:

SD77 Newbie

Hope this clears things up concerning L-glutamine; I don't think supplements are necessary, especially since the supplements might not exactly mimic the naturally made L-glutamine in your body.

Quoted from website (listed below)

L-glutamine is the most prevalent amino acid in the blood. Human cells readily manufacture L-glutamine and under normal circumstances, dietary intake and production of L-glutamine is sufficient. However, in times of stress or increased energy output, the body's tissues need more L-glutamine than usual, making supplementation important.

L-glutamine can be found in beans, brewer's yeast, brown rice bran, dairy products, eggs, fish, legumes, meat, nuts, seafood, seeds, soy, whey, whole grains and beet root.

Scientists also believe that deficiency in L-glutamine may be linked to gastrointestinal disorders such as irritable bowel syndrome, Crohn's disease, and colon inflammation. Supplementation may improve symptoms of these disorders while supporting overall health of the intestines.(4, 5)

One of L-glutamine's most important functions involves the support of cellular energy, growth and repair.

Finally, because L-glutamine supports the growth of new cells, it may be useful in the enhancement of wound healing. Wounds such as burns, surgical and traumatic wounds, cuts, and others may heal faster with supplementation.(12, 13)

Open Original Shared Link

codetalker Contributor
That part about glutamic acid set off some alarm bells in my head too. For some reason I did not take the L-glutamine my ND recommended. Maybe it's just as well??? :huh:

Would you be willing to share info about the recommendation of your ND? I would be very interested in recommended dosage (i.e. milligrams), frequency (times per day) and how long the L-glutamine should be taken (i.e. one week, one month, indefinitely).

The reason I ask is that I found one article on the web that said that the OTC capsules contained amounts of L-glutamine that were too low to be beneficial.

mushroom Proficient
Would you be willing to share info about the recommendation of your ND? I would be very interested in recommended dosage (i.e. milligrams), frequency (times per day) and how long the L-glutamine should be taken (i.e. one week, one month, indefinitely).

The reason I ask is that I found one article on the web that said that the OTC capsules contained amounts of L-glutamine that were too low to be beneficial.

I will have to go back and check it out; will get back to you.

lonewolf Collaborator

That was fascinating! The section about kidney disease was especially interesting to me. I was diagosed with a kidney disease back at a time when I was trying to reintroduce gluten grains (spelt, not wheat) into my diet. The disease completely went into remission when I went fanatically gluten-free and I have not had a problem for 5-1/2 years. I've had people tell me that it was just a coincidence, but this article gave my theory about what helped me some credence!

mushroom Proficient
That was fascinating! The section about kidney disease was especially interesting to me. I was diagosed with a kidney disease back at a time when I was trying to reintroduce gluten grains (spelt, not wheat) into my diet. The disease completely went into remission when I went fanatically gluten-free and I have not had a problem for 5-1/2 years. I've had people tell me that it was just a coincidence, but this article gave my theory about what helped me some credence!

I did not know what to make of the part about kidney disease. I have borne the diagnosis CKD for five years now, made in my still-eating-gluten days when my RA was being treated with diclofenac and sulfsalazine. They told me that the diclofenac had shut my kidneys down, that I was practically in kidney failure, and have always since then had problems with creatinine and BUN levels. But I have just been told by a nephrologist that my kidneys are actually in pretty good shape and are functioning much better than the tests suggest. I don't know if the gluten played any part in any of this because I had not been on the diclofenac for very long and had certainly not exceeded any dosages :blink: :blink:

mushroom Proficient
I will have to go back and check it out; will get back to you.

I am sorry, I have looked, but could not find the bottle; maybe I threw it out or perhaps did not even buy it... it was a while ago.

codetalker Contributor
I am sorry, I have looked, but could not find the bottle; maybe I threw it out or perhaps did not even buy it... it was a while ago.

Thanks for checking.

SD77 Newbie

If you did find this article interesting, you might want to read 'Ishmael' by Daniel Quinn...the book is a bit hard to get into at first, (published at least a decade ago) but it describes the idea of that the 'agriculture revolution' wasn't necessary the best idea.. (aka wheat and dairy as we know it). Wheat was the easiest grain to grown, and cows were the easiest animal to tame, therefore, our culture was grown upon these ideas...when I first read this article, 'Ishmael' was the first book I thought of...

Shannon

  • 5 months later...
Brookesmom Newbie

I don't see the link! Just a link about spammers link here.... COuld you repost it? Sounds so interesting..

thanks.

David in Seattle Explorer

I don't see the link! Just a link about spammers link here.... COuld you repost it? Sounds so interesting..

thanks.

That's all I get too, looks like the moderators pulled it, perhaps? After everyone raved about it? WHY??

Tried inserting various links, none of them seemed to work from this site. It would be nice to at least be told WHY.

Jestgar Rising Star
Open Original Shared Link

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - knitty kitty replied to Jane02's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

    2. - Jane02 replied to Jane02's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

    3. - knitty kitty replied to Jane02's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

    4. 0

      Penobscot Bay, Maine: Nurturing Gluten-Free Wellness Retreat with expert celiac dietitian, Melinda Dennis

    5. - Scott Adams replied to Jane02's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,329
    • Most Online (within 30 mins)
      7,748

    klkarius
    Newest Member
    klkarius
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • knitty kitty
      @Jane02, I hear you about the kale and collard greens.  I don't do dairy and must eat green leafies, too, to get sufficient calcium.  I must be very careful because some calcium supplements are made from ground up crustacean shells.  When I was deficient in Vitamin D, I took high doses of Vitamin D to correct the deficiency quickly.  This is safe and nontoxic.  Vitamin D level should be above 70 nmol/L.  Lifeguards and indigenous Pacific Islanders typically have levels between 80-100 nmol/L.   Levels lower than this are based on amount needed to prevent disease like rickets and osteomalacia. We need more thiamine when we're physically ill, emotionally and mentally stressed, and if we exercise like an athlete or laborer.  We need more thiamine if we eat a diet high in simple carbohydrates.  For every 500 kcal of carbohydrates, we need 500-1000 mg more of thiamine to process the carbs into energy.  If there's insufficient thiamine the carbs get stored as fat.  Again, recommended levels set for thiamine are based on minimum amounts needed to prevent disease.  This is often not adequate for optimum health, nor sufficient for people with absorption problems such as Celiac disease.  Gluten free processed foods are not enriched with vitamins like their gluten containing counterparts.  Adding a B Complex and additional thiamine improves health for Celiacs.  Thiamine is safe and nontoxic even in high doses.  Thiamine helps the mitochondria in cells to function.  Thiamine interacts with each of the other B vitamins.  They are all water soluble and easily excreted if not needed. Interesting Reading: Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet https://pubmed.ncbi.nlm.nih.gov/19154566/ Safety and effectiveness of vitamin D mega-dose: A systematic review https://pubmed.ncbi.nlm.nih.gov/34857184/ High dose dietary vitamin D allocates surplus calories to muscle and growth instead of fat via modulation of myostatin and leptin signaling https://pubmed.ncbi.nlm.nih.gov/38766160/ Safety of High-Dose Vitamin D Supplementation: Secondary Analysis of a Randomized Controlled Trial https://pubmed.ncbi.nlm.nih.gov/31746327/ Vitamins and Celiac Disease: Beyond Vitamin D https://pmc.ncbi.nlm.nih.gov/articles/PMC11857425/ Investigating the therapeutic potential of tryptophan and vitamin A in modulating immune responses in celiac disease: an experimental study https://pubmed.ncbi.nlm.nih.gov/40178602/ Investigating the Impact of Vitamin A and Amino Acids on Immune Responses in Celiac Disease Patients https://pmc.ncbi.nlm.nih.gov/articles/PMC10814138/
    • Jane02
      Thank you so much @knitty kitty for this insightful information! I would have never considered fractionated coconut oil to be a potential source of GI upset. I will consider all the info you shared. Very interesting about the Thiamine deficiency.  I've tracked daily averages of my intake in a nutrition software. The only nutrient I can't consistently meet from my diet is vitamin D. Calcium is a hit and miss as I rely on vegetables, dark leafy greens as a major source, for my calcium intake. I'm able to meet it when I either eat or juice a bundle of kale or collard greens daily haha. My thiamine intake is roughly 120% of my needs, although I do recognize that I may not be absorbing all of these nutrients consistently with intermittent unintentional exposures to gluten.  My vitamin A intake is roughly 900% (~6400 mcg/d) of my needs as I eat a lot of sweet potato, although since it's plant-derived vitamin A (beta-carotene) apparently it's not likely to cause toxicity.  Thanks again! 
    • knitty kitty
      Hello, @Jane02,  I take Naturewise D 3.  It contains olive oil.   Some Vitamin D supplements, like D Drops, are made with fractionated coconut oil which can cause digestive upsets.  Fractionated coconut oil is not the same as coconut oil used for cooking.  Fractionated coconut oil has been treated for longer shelf life, so it won't go bad in the jar, and thus may be irritating to the digestive system. I avoid supplements made with soy because many people with Celiac Disease also react to soy.  Mixed tocopherols, an ingredient in Thornes Vitamin D, may be sourced from soy oil.  Kirkland's has soy on its ingredient list. I avoid things that might contain or be exposed to crustaceans, like Metagenics says on its label.  I have a crustacean/shellfish/fish allergy.  I like Life Extension Bioactive Complete B Complex.  I take additional Thiamine B 1 in the form Benfotiamine which helps the intestines heal, Life Extension MegaBenfotiamine. Thiamine is needed to activate Vitamin D.   Low thiamine can make one feel like they are getting glutened after a meal containing lots of simple carbohydrates like white rice, or processed gluten free foods like cookies and pasta.   It's rare to have a single vitamin deficiency.  The water soluble B Complex vitamins should be supplemented together with additional Thiamine in the form Benfotiamine and Thiamine TTFD (tetrahydrofurfuryl disulfide) to correct subclinical deficiencies that don't show up on blood tests.  These are subclinical deficiencies within organs and tissues.  Blood is a transportation system.  The body will deplete tissues and organs in order to keep a supply of thiamine in the bloodstream going to the brain and heart.   If you're low in Vitamin D, you may well be low in other fat soluble vitamins like Vitamin A and Vitamin K. Have you seen a dietician?
    • Scott Adams
      I do not know this, but since they are labelled gluten-free, and are not really a product that could easily be contaminated when making them (there would be not flour in the air of such a facility, for example), I don't really see contamination as something to be concerned about for this type of product. 
    • trents
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.