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Celiac Vaccine?


fallout1

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fallout1 Rookie

Has anyone heard anything much about this Australian study ? I read the abstract in the journal itself and it didn't mention any vaccine trials.

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K-Dawg Explorer

Last para. of the article reads as follows:

"The Australian team has begun an early-stage clinical trial using these peptides in a vaccine that aims to desensitize celiac patients and make them tolerant of the compounds. The group expects to report preliminary safety results later this year."

Glad you posted this -- very interesting.

Has anyone heard anything much about this Australian study ? I read the abstract in the journal itself and it didn't mention any vaccine trials.

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Emilushka Contributor

My doc mentioned it at my appointment. Not sure how long it'll take to get to the US for trials. I'm sure it depends on how much success the Australians have.

runningcrazy Contributor

I think it would be risky to make a vaccine for this. If your body is not meant to process gluten, then its not meant to process gluten. Why would you inject something into your body to stop your bodies natural reaction to what is pretty much seen as a poison to your body? I think that most if not everyone would benefit on a gluten free diet and that more effort should be put into making gluten free options more widespread and less spent on trying to stop celiac.

Just my thoughts :P

Emilushka Contributor

I think it would be risky to make a vaccine for this. If your body is not meant to process gluten, then its not meant to process gluten. Why would you inject something into your body to stop your bodies natural reaction to what is pretty much seen as a poison to your body? I think that most if not everyone would benefit on a gluten free diet and that more effort should be put into making gluten free options more widespread and less spent on trying to stop celiac.

Just my thoughts :P

If they had a vaccine for hay fever, I'd take that too! My body isn't always the smartest. If I can help educate it or prevent it from damaging itself over something that's not ACTUALLY harmful, I'll totally take the vaccine.

Maybe I just really miss lasagna today.

cassP Contributor

I think it would be risky to make a vaccine for this. If your body is not meant to process gluten, then its not meant to process gluten. Why would you inject something into your body to stop your bodies natural reaction to what is pretty much seen as a poison to your body? I think that most if not everyone would benefit on a gluten free diet and that more effort should be put into making gluten free options more widespread and less spent on trying to stop celiac.

Just my thoughts :P

AMEN exactly my thoughts!!! Dont even get me started. Im not even sure how it makes any sense for them to create a vaccine to help the body NOT react in its natural supremely intelligent manner... But believe u me, they WILL make one- there is just way too much money to be made on this!!! And thats what our medical system is all about- money... And then after they actually have a way to make money off of it- they'll actually start talking about it instead of IBS! Oh and they'll also add it to the mandatory schedule for babies.

gaingus Rookie

I think it would be risky to make a vaccine for this. If your body is not meant to process gluten, then its not meant to process gluten. Why would you inject something into your body to stop your bodies natural reaction to what is pretty much seen as a poison to your body? I think that most if not everyone would benefit on a gluten free diet and that more effort should be put into making gluten free options more widespread and less spent on trying to stop celiac.

Just my thoughts :P

I have to agree. We have a genetic reason as to why we are this way. If we get glutened, sure we can take things to help with the symptoms just like if we had a virus. I think confusing our immune systom into processing something that is, how should I put this.... Poison to our bodies could end up causing more damage. I know a lot of us (me included) did years worth of damage by eating gluten just because we didn't know. Until an actual cure is found, it is a disease plain and simple. I think that money could be used for finding cures for diseases that people die from more than celiac does, HIV/AIDS for example. For me, I will just stick with the diet until there is documented proof of a cure, and I really don't see that happening in my life time.


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Skylark Collaborator

If they find a working vaccine I'll be first in line. I don't mind living without wheat, but constant vigilance against cross-contamination and hidden gluten is no fun at all. I'm vitamin D deficient even after 5 years gluten-free and I have to wonder how much damage there is from traces of gluten in my supposedly gluten-free food.

I agree that I'd rather see efforts going into illnesses that don't have a dietary cure, but market-driven healthcare doesn't work that way. It is an overall weakness in the entire US approach to medicine and biomedical research.

Salax Contributor

I think it would be risky to make a vaccine for this. If your body is not meant to process gluten, then its not meant to process gluten. Why would you inject something into your body to stop your bodies natural reaction to what is pretty much seen as a poison to your body? I think that most if not everyone would benefit on a gluten free diet and that more effort should be put into making gluten free options more widespread and less spent on trying to stop celiac.

Just my thoughts :P

I agree. Besides who says flour/wheat is actually good for the body? No so much, maybe back in the old days when it was truly natural and organic, today they have "high" gluten, "super" gluten and everything is GMO. So in my mind the body might be right in this case, attack the evil gluten! Stuffs bad for people. ;)

  • 2 months later...
fallout1 Rookie

Medicine counters "nature" all the time. Just because it's "natural" doesn't make it sacrosanct. If we can find a way to safely allow ingestion of gluten I'll be the first to sign up. Especially if it means never having to eat or drink the sorry gluten-free excuses (empty, high-glycemic grains) for bread and beer again.

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    • Rogol72
      Hey @Butch68, I also have dermatitis herpetiformis but don't suffer from it anymore. I used to drink Guinness too but I drink Cider now when out on social occasions. I assume you are in Ireland or the UK. If it's any good to you ... 9 White Deer based in Cork brew a range of gluten-free products including a gluten-free Stout. I'm not sure if they are certified though. https://www.9whitedeer.ie/ I haven't come across any certified gluten-free stouts this side of the pond.
    • Scott Adams
      This is a very common question, and the most important thing to know is that no, Guinness is not considered safe for individuals with coeliac disease. While it's fascinating to hear anecdotes from other coeliacs who can drink it without immediate issues, this is a risky exception rather than the rule. The core issue is that Guinness is brewed from barley, which contains gluten, and the standard brewing process does not remove the gluten protein to a level safe for coeliacs (below 20ppm). For someone like you who experiences dermatitis herpetiformis, the reaction is particularly significant. DH is triggered by gluten ingestion, even without immediate gastrointestinal symptoms. So, while you may not feel an instant stomach upset, drinking a gluten-containing beer like Guinness could very well provoke a flare-up of your skin condition days later. It would be a gamble with a potentially uncomfortable and long-lasting consequence. Fortunately, there are excellent, certified gluten-free stouts available now that can provide a safe and satisfying alternative without the risk.
    • MogwaiStripe
      Interestingly, this thought occurred to me last night. I did find that there are studies investigating whether vitamin D deficiency can actually trigger celiac disease.  Source: National Institutes of Health https://pmc.ncbi.nlm.nih.gov/articles/PMC7231074/ 
    • Butch68
      Before being diagnosed coeliac I used to love Guinness. Being made from barley it should be something a coeliac shouldn’t drink. But taking to another coeliac and they can drink it with no ill effects and have heard of others who can drink it too.  is this everyone’s experience?  Can I drink it?  I get dermatitis herpetiformis and don’t get instant reactions to gluten so can’t try it to see for myself. 
    • trents
      NCGS does not cause damage to the small bowel villi so, if indeed you were not skimping on gluten when you had the antibody blood testing done, it is likely you have celiac disease.
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