Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Do You Need An Intact Blister?

dilettantesteph

By dilettantesteph
in Dermatitis Herpetiformis

Recommended Posts

dilettantesteph Collaborator
dilettantesteph
Posted

I thought that the biopsy was supposed to be adjacent to a blister. Why should it matter whether or not the blister is intact? It is really hard not to scratch so that it stays intact. Plus, the doctor said that it is the blister which is biopsied until I said that I thought it was next to the blister where you were supposed to biopsy. Does she know what she is doing?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


jerseyangel Proficient
jerseyangel
Posted

I thought that the biopsy was supposed to be adjacent to a blister. Why should it matter whether or not the blister is intact? It is really hard not to scratch so that it stays intact. Plus, the doctor said that it is the blister which is biopsied until I said that I thought it was next to the blister where you were supposed to biopsy. Does she know what she is doing?

The doctor is wrong, Steph--the biopsy needs to be done on skin adjacent to the blister, not the blister itself.

kareng Grand Master
kareng
Posted

Trying showing the derm this from the Univ of Chicago Celiac Center.

Open Original Shared Link

dilettantesteph Collaborator
dilettantesteph
Posted
  • Author

Is it possible that you need an intact blister even if you biopsy next to it? It is this doctor or wait until I move to a new area. She is one of those doctors who already knows everything and is unwilling to listen. When asked a question she didn't know she just answered with a bunch of stuff she did know.

Hopeful1950 Explorer
Hopeful1950
Posted

The blisters of DH tend to be fragile and I have rarely seen one for the reasons you have described. I feel the itch and rub or scratch and they're gone. All she needs is an active lesion to biopsy next to. You'll have to point her to the active lesion if she needs a blister to find it....ha, ha. She made need a blister to biopsy for other things, but not for DH. If she biopsies on a blister/lesion, she won't find any antibodies because they will be gone. Be persistent and take your medical research with you to show her. I hope she will be receptive.

mushroom Proficient
mushroom
Posted

I could not find anything that requires the blister to be intact.

Open Original Shared Link

Diagnosis is through immunofluorescence staining on a skin biopsy taken near a group of blisters, not from the blister itself. In patients with DH, the test will show IgA antibodies in the skin. Open Original Shared Link

dilettantesteph Collaborator
dilettantesteph
Posted
  • Author

Shoot. She is supposed to be the best in the area. I knew it wasn't looking good when she recommended oatmeal baths.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mushroom Proficient
mushroom
Posted

Shoot. She is supposed to be the best in the area. I knew it wasn't looking good when she recommended oatmeal baths.

:unsure:

:(

eatmeat4good Enthusiast
eatmeat4good
Posted

I've never seen an intact blister either.

That's part of the reason it went undiagnosed for so long.

Definitely not blistered looking.

They rub off or scratch off as soon as they form.

I hope you get a result, but if not, you can be gluten free anyway.

I couldn't believe how bad the iodine reation was.

I hope you heal fast.

dilettantesteph Collaborator
dilettantesteph
Posted
  • Author

I hope you get a result, but if not, you can be gluten free anyway.

I couldn't believe how bad the iodine reation was.

I hope you heal fast.

I've been gluten free for over 3 years. The biopsy was just for conformation, which it looks like I won't be getting any time soon. Tell me about the iodine reaction.

eatmeat4good Enthusiast
eatmeat4good
Posted

It was just as if I had eaten gluten. Sores that had healed reopened. Some filled with fluid and hurt hurt hurt.

Itch, burn, sting, hurt.

It has taken me two weeks to get them healed after eating crawfish.

Shellfish have iodine. Also table salt. If your antibodies are still in the skin you can have a very bad reaction.

Iodine reactivates the antibodies.

I'm starting Dapsone because I am soooo sensitive to iodine now with no end in sight.

The antibodies remain in your skin for up to 10 years and the sores can take up to 6 months to 2 years to heal.

dilettantesteph Collaborator
dilettantesteph
Posted
  • Author

It was just as if I had eaten gluten. Sores that had healed reopened. Some filled with fluid and hurt hurt hurt.

Itch, burn, sting, hurt.

It has taken me two weeks to get them healed after eating crawfish.

Shellfish have iodine. Also table salt. If your antibodies are still in the skin you can have a very bad reaction.

Iodine reactivates the antibodies.

I'm starting Dapsone because I am soooo sensitive to iodine now with no end in sight.

The antibodies remain in your skin for up to 10 years and the sores can take up to 6 months to 2 years to heal.

I am sorry that you have been suffering like that. How long have you been gluten free?

eatmeat4good Enthusiast
eatmeat4good
Posted

Only 4 months.

Just started taking Dapsone.

Seems to be working well.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      132,019
    • Most Online (within 30 mins)
      7,748
    Wilson1984
    Newest Member
    Wilson1984
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • sleuth
      Nicotine Gum For Gluten Symptoms.. Am I Crazy?

      By sleuth · Posted

      He is not just a psychiatrist.  He is also a neuroscientist.  And yes, I have already read those studies.   I agree with benfotiamine.  This is short term while glutened/inflammation occurs.  As I had already mentioned, these symptoms no longer exist when this phase passes.  And yes, I know that celiac is a disease of malnutrition.  We are working with a naturopath.
    • knitty kitty
      Nicotine Gum For Gluten Symptoms.. Am I Crazy?

      By knitty kitty · Posted

      Please do more research before you settle on nicotine. Dr. Paul New house is a psychiatrist.  His latest study involves the effect of nicotine patches on Late Life Depression which has reached no long term conclusions about the benefits.   Effects of open-label transdermal nicotine antidepressant augmentation on affective symptoms and executive function in late-life depression https://pubmed.ncbi.nlm.nih.gov/39009312/   I'm approaching the subject from the Microbiologist's point of view which shows nicotine blocks Thiamine B1 uptake and usage:   Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells https://pubmed.ncbi.nlm.nih.gov/26633299/   While supplementation with thiamine in the form Benfotiamine can protect from damage done by  nicotine: Benfotiamine attenuates nicotine and uric acid-induced vascular endothelial dysfunction in the rat https://pubmed.ncbi.nlm.nih.gov/18951979/   I suggest you study the beneficial effects of Thiamine (Benfotiamine and TTFD) on the body and mental health done by Dr. Derrick Lonsdale and Dr. Chandler Marrs.  Dr. Lonsdale had studied thiamine over fifty years.   Hiding in Plain Sight: Modern Thiamine Deficiency https://pmc.ncbi.nlm.nih.gov/articles/PMC8533683/ I suggest you read their book Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition.     Celiac Disease is a disease of malabsorption causing malnutrition.  Thiamine and benfotiamine: Focus on their therapeutic potential https://pmc.ncbi.nlm.nih.gov/articles/PMC10682628/
    • sleuth
      Nicotine Gum For Gluten Symptoms.. Am I Crazy?

      By sleuth · Posted

      Thanks for your response.  Everything you mentioned he is and has been doing.  Tobacco is not the same as nicotine.  Nicotine, in the form of a patch, does not cause gastrointestinal irritation.  Smoking does. He is not smoking.  Please do your research before stating false information. Dr. Paul Newhouse has been doing research on nicotine the last 40 years at Vanderbilt University Medical Center.  
    • Jmartes71
      Fighting for a name

      By Jmartes71 · Posted

      Im so frustrated and still getting the run around trying to reprove my celiac disease which my past primary ignored for 25 years.I understand that theres a ray of medical that doctors are limited too but not listening and telling the patient ( me) that im not as sensitive as I think and NOT celiac!Correction Mr white coat its not what I think but for cause and affect and past test that are not sticking in my medical records.I get sick violently with foods consumed, not eating the foods will show Im fabulous. After many blood draws and going through doctors I have the HLA- DQ2 positive which I read in a study that Iran conducted that the severity in celiac is in that gene.Im glutenfree and dealing with related issues which core issue of celiac isn't addressed. My skin, right eye, left leg diagestive issues affected. I have high blood pressure because im in pain.Im waisting my time on trying to reprove that Im celiac which is not a disease I want, but unfortunately have.It  has taken over my life personally and professionally. How do I stop getting medically gaslight and get the help needed to bounce back if I ever do bounce back to normal? I thought I was in good care with " celiac specialist " but in her eyes Im good.Im NOT.Sibo positive, IBS, Chronic Fatigue just to name a few and its all related to what I like to call a ghost disease ( celiac) since doctors don't seem to take it seriously. 
    • trents
      Celiac getting dentures

      By trents · Posted

      @Martha Mitchell, your reaction to the lens implant with gluten sounds like it could be an allergic reaction rather than a celiac reaction. It is possible for a celiac to be also allergic to gluten as it is a protein component in wheat, barley and rye.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.