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Celiac Testing


Sam81

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Sam81 Apprentice

I was just wondering if any one knows if a colonoscopy can confirm/disprove celiac DH (dermatitis herpetiformis)??


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psawyer Proficient

Yes, I do, and no, it cannot. The intestinal damage caused by celiac disease is in the small intestine, not the colon.

kareng Grand Master

No. DH is a skin problem. A Dermatologist biopsies next to the "pimple" & it is sent to the pathologist for a microscopic look.

An endoscopy is used to diagnosis the small intestine damage from Celiac. Multiple Biopsies are taken of the small intestine & looked at microscopically. A colonoscopy is the large intestine so your confused doctor is looking in the wrong places.

Sam81 Apprentice

Ok, thank you. Mr Dr is convinced I do not have celiac - despite ticking all boxes bar 1. I'm in the UK and have heard of a test you can by over the counter - "Biocard Celiac Test - Gluten Sensitivity test kit". Has anyone bought and tried this? Does it work and does it hold any weight with Dr's??

It really isn't that I want to have Celiac but it's the age old NEED to have an answer to all my discomfort and a piece of paper to hand to people to say - "Look - I'm not imagining it!"

I'm 30 on Monday and feel more like 70. Ridiculous.

pgrovetom Rookie

I was just wondering if any one knows if a colonoscopy can confirm/disprove celiac DH (dermatitis herpetiformis)??

Yes a Colonoscopy can confirm Celiac if the doctor doing it does a biopsy of the intestines after reaching the end of the colon. When I had my Colonoscopy, the GI doc did a Celiac biopsy since he was already in there and could get the biopsy from my lower intestines... If the GI doc only examines the colon as per a normal colonoscopy, no it does no good. Since an endoscopy is easier than a colonoscopy, they usually do the biopsy from the topside. I had both.

In any case, biopsies are better at confirming than ruling out Celiac. The doctor takes a sample of the intestinal lining for later examination under a microscope. If they see the damage from Celiac, its a sure thing. If they don't, it either means you don't have Celiac or they took the biopsy from a healthy area or the Gluten had yet to damage the intestinal lining. In general, ruling things out is a risky game. If something like Celiac is "ruled out" and in error, it will be a long time before they eventually run into something that suggests "un-ruling it out".

This is a very common problem in medicine and is due to cost control. When studies are done in medicine, they actually follow a proper scientific and statistically proper approach by using careful controls, large populations and double blind technique in order not to come to a conclusion in error. Regular medicine abandons this very appropriate method in favor of saving money at the expense of proper diagnosis.

If you are planning to have a colonoscopy, ask your GI doc if they can take a Celiac biopsy from the lower intestine just above the colon. If you already had it and they didn't do that biopsy, it means nothing with regard to Celiac.

psawyer Proficient

It would be better to do an endoscopy of the duodenum (upper part of the small intestine) at the same time as the colonoscopy. There is no extra prep required. I had that done when I was diagnosed. The colonoscopy will not detect celiac, but should be done to screen for other conditions which may exist.

ravenwoodglass Mentor

Yes a Colonoscopy can confirm Celiac if the doctor doing it does a biopsy of the intestines after reaching the end of the colon. When I had my Colonoscopy, the GI doc did a Celiac biopsy since he was already in there and could get the biopsy from my lower intestines... If the GI doc only examines the colon as per a normal colonoscopy, no it does no good. Since an endoscopy is easier than a colonoscopy, they usually do the biopsy from the topside. I had both.

In any case, biopsies are better at confirming than ruling out Celiac. The doctor takes a sample of the intestinal lining for later examination under a microscope. If they see the damage from Celiac, its a sure thing. If they don't, it either means you don't have Celiac or they took the biopsy from a healthy area or the Gluten had yet to damage the intestinal lining. In general, ruling things out is a risky game. If something like Celiac is "ruled out" and in error, it will be a long time before they eventually run into something that suggests "un-ruling it out".

This is a very common problem in medicine and is due to cost control. When studies are done in medicine, they actually follow a proper scientific and statistically proper approach by using careful controls, large populations and double blind technique in order not to come to a conclusion in error. Regular medicine abandons this very appropriate method in favor of saving money at the expense of proper diagnosis.

If you are planning to have a colonoscopy, ask your GI doc if they can take a Celiac biopsy from the lower intestine just above the colon. If you already had it and they didn't do that biopsy, it means nothing with regard to Celiac.

I have never heard of a doctor doing a biopsy of the small intestine with a colonoscopy. Since you say you had both scopes done at the same time I suspect the biopsies were taken during the endo not the colonoscopy.


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    • Scott Adams
      If your tTg-IgA was 28 and positive is at 3, you are nearly 10x over the positive marker, so the most likely explanation by far would be celiac disease. I also do not understand why your doctor would not want to run the blood test, which is the normal first step in the diagnosis process.
    • xxnonamexx
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    • trents
      So the tTG-IGA at 28 is positive for celiac disease. There are some other medical conditions that can cause elevated tTG-IGA but this is unlikely. There are some people for whom the dairy protein casein can cause this but by far the most likely cause is celiac disease. Especially when your small bowel lining is "scalloped". Your Serum IGA 01 (aka, "total IGA") at 245 mg/dl is within normal range, indicating you are not IGA deficient. But I also think it would be wise to take your doctor's advice about the sucraid diet and avoiding dairy . . . at least until you experience healing and your gut has had a chance to heal, which can take around two years. After that, you can experiment with adding dairy back in and monitor symptoms. By the way, if you want the protein afforded by dairy but need to avoid casein, you can do so with whey protein powder. Whey is the other major protein in dairy.
    • jenniber
      hi, i want to say thank you to you and @trents   . after 2 phone calls to my GI, her office called me back to tell me that a blood test was “unnecessary” and that we should “follow the gold standard” and since my biopsy did not indicate celiac, to follow the no dairy and sucraid diet. i luckily have expendable income and made an appt for the labcorp blood test that day. i just got my results back and it indicates celiac disease i think 😭   im honestly happy bc now i KNOW and i can go gluten free. and i am SO MAD at this doctor for dismissing me for a simple blood test that wouldn’t have cost her anything !!!!!!!!!!! im sorry, im so emotional right now, i have been sick my whole life and never knew why, i feel so much better already   my results from labcorp:   Celiac Ab tTG TIgA w/Rflx Test Current Result and Flag Previous Result and Date Units Reference Interval t-Transglutaminase (tTG) IgA 01 28 High U/mL 0-3 Negative 0 - 3 Weak Positive 4 - 10 Positive >10 Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy. Immunoglobulin A, Qn, Serum 01 245 mg/dL 87-352
    • JoJo0611
      Thank you this really helped. 
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