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Exact Opposite Reaction To Meds?

Duhlina

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Duhlina Apprentice
Duhlina
Posted

All my life I seem to have the exact opposite reaction to medications. If I take Nyquil, it's like speed and I'm up all night, same with Benadryl - most people take these and are down for the count. I also seem to have a very high tolerance to pain meds. Basically nothing works. The last time I went to the ER I had an abscessed tooth. They ended up prescribing me Dilaudid (morphine derivative) because nothing else works....well, Darvocet worked but it's been taken off the market. Even the Dilaudid did squat for me! Nothing works! I end up taking one more than I should and then I get sick from it.

Is this something that the celiac causes? Am I the only person that has this symptom?

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lovegrov Collaborator
lovegrov
Posted

I know folks without celiac who have the same thing with Nyqui and Benadryl. And some folks simply have a high resistance to pain meds. Pretty hard to pin it on celiac.

richard

Jestgar Rising Star
Jestgar
Posted

It can happen to anyone. It's related to body chemistry, not celiac disease.

love2travel Mentor
love2travel
Posted

I have always had this problem as well but do not see a link to my celiac. Benadryl, morphine, Demerol, Oxycontin - you name it, they have kept me wired and wide awake! :angry:

However, my chronic pain management doctor told me that those with fibromyalgia (myself) are extremely sensitive to meds and that side effects can be much worse than those who do not have FMS. And as FMS is an auto-immune disease as well, who knows whether there is a correlation? :huh:

Strawberry-Jam Enthusiast
Strawberry-Jam
Posted

I have the same problem. There are some medicines like that which keep me up but if I take half the dose they put me down.

Caffeine makes me alert if I have one cup of tea, and sleepy if I have a cup of coffee's worth or more.

Pain medications don't work for my headaches, but do help with cramps so idk if I am immune to pain meds or if only my headaches are immune to pain meds.

My mother has the same problem but does not have celiac.

mushroom Proficient
mushroom
Posted

Yeah, Nyquil, Benadryl = speed; sleeping pills = insomnia, antidepressants (well, the only one I ever took) made me depressed), pain meds - the onlly thing that works is Demerol (all morphine derivatives make me vomit :huh: , Tylenol will take the edge off something mild :) I am a contrarian when it comes to most meds :blink: But I don't know of a connection to celiac.

T.H. Community Regular
T.H.
Posted

Theoretically, it could contribute.

Celiacs don't just absorb nutrients properly, we can potentially not absorb meds properly as well, when we're undiagnosed. So some ingredients of the meds may be absorbing at different rates than they should, or in different amounts than they should, so they might be having different effects. The side effects might be more likely to occur if we're not absorbing the meds properly, possibly.

That said, my GI doc (he's the celiac go-to guy in my city) said that a much higher percentage of his patients with celiac disease seem to have more issues with medicine side effects. I know that myself, my daughter, and my grandmother (who we suspect had it) always get lots of bizarro side effects to medicines we've had to take.

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mushroom Proficient
mushroom
Posted

Theoretically, it could contribute.

Celiacs don't just absorb nutrients properly, we can potentially not absorb meds properly as well, when we're undiagnosed. So some ingredients of the meds may be absorbing at different rates than they should, or in different amounts than they should, so they might be having different effects. The side effects might be more likely to occur if we're not absorbing the meds properly, possibly.

That said, my GI doc (he's the celiac go-to guy in my city) said that a much higher percentage of his patients with celiac disease seem to have more issues with medicine side effects. I know that myself, my daughter, and my grandmother (who we suspect had it) always get lots of bizarro side effects to medicines we've had to take.

Could be, although I would think (hope :o ) I am absorbing better now. Just had a "bizarro" summer where I was tried on lots of different meds and reacted to most of them in one way or another that meant I couldn't take them. I even reacted to meds (two antibiotics) I have tolerated fine before. The fewer meds I take the better :ph34r:

pricklypear1971 Community Regular
pricklypear1971
Posted

I'm one of those that overreacts. Recently to corticosteroids, antibiotics....,

Ironically I can drink coffee all night and go to sleep in a blink. But give me ONE EXCEDRIN....and I'm cleaning my room and reorganizing drawers with a 102+ fever.

I'm just weird.

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