When I underwent a scope three years ago, the GI told me I was negative for celiac because there was no intestinal damage (in spite of multiple strong positive labs). I went back to look at my biopsy report out of curiosity, and found this note:
“Localized mild nodular mucosa was found in the duodenal bulb. Duodenum otherwise normal.”
The pathology from this scope was negative. Does anyone have any insight into mild modular mucosa and what that could indicate or be a precursor to? I’ve read it can be a sign of celiac or other gut issues like h. Pylori, etc.
Thanks in advance!
You're welcome!
Be sure the patient eats at least ten grams of gluten per day for a minimum of two weeks prior to repeating antibody testing.
Some people unconsciously reduce the amount of gluten in their diet because the feel unwell. Three grams of gluten per day is sufficient to produce symptoms. Only at ten grams or more is the immune system provoked to raise the antibody production high enough so that the antibodies leave the digestive tract and enter the blood stream where they can be measured.
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Thanks for your response and thoughts. Total IgA is normal. HLA DQ2/DQ8 came as heterozygous and the interpretation of the lab that the risk of coeliac disease is mild to moderate. Thyroid function test is normal. I agree that the best way is to repeat tTG antibodies in 6 months time as the result was not massively high.