Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

IGA deficiency

Jadeashlyn
 Share

Recommended Posts

Jadeashlyn Newbie
Jadeashlyn
Posted

Hi, long journey for my 4yo. Initial investigations were negative tTGA. But drs still couldn’t figure out why she wasn’t absorbing iron, nutrient deficiencies despite a great diet. Recent test shows she is severely IGA deficient. Also positive for one of the gene mutations for celiac. I’ve now learned that being IGA deficient can easily cause false negatives of normal screens. I looked back through tests and saw that her EMA was 10 which is exactly the borderline cut off for being positive. 
 

But because it was not flagged and right on the cusp of positive no one asked to follow up. I’ve made an appt anyway. What is the next step in having her tested since she is IGA deficient as well as genetic positive and her EMA was so borderline? 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


RMJ Mentor
RMJ
Posted

Celiac tests can look at either IgA and IgG antibodies.  If she is IgA deficient she should have the IgG tests.  Can you post the full names of the tests that she has had? Sometimes only the IgA tests are run.

trents Grand Master
trents
Posted
(edited)

Good advice from RMJ. There is also the option of putting her on a strict gluten free diet and see if the symptoms improve. It is also common for celiacs to be dairy intolerant, either to the lactose or the casein in dairy.

Edited by trents
Scott Adams Grand Master
Scott Adams
Posted

Some people are naturally IGA deficient, and if this is the case, then certain blood tests for celiac disease might be false-negative, and other types of tests need to be done to make an accurate diagnosis. The article includes the "Mayo Clinic Protocol," which is the best overall protocol for results to be ~98% accurate.

 

 

knitty kitty Grand Master
knitty kitty
Posted

Anemia and Thiamine insufficiency can cause poor antibody production.  Ask for an Erythrocyte Transketolase test to check thiamine level.  

Which nutrients is she deficient in?  Are those deficiencies being corrected?  

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      130,375
    • Most Online (within 30 mins)
      7,748
    KEALBO
    Newest Member
    KEALBO
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Katerific
      Lymphocytic Colitis with Celiac

      By Katerific · Posted

      I was diagnosed with microscopic colitis and celiac a couple of years ago.  The GI doctor prescribed a course of budesonide, which moderately helped until I tapered off.    After a lot of ups and downs over the course of 2 years, I am finally in microscopic colitis remission.  Since I am also diabetic, I was started on metformin and Jardiance.  Metformin by itself helped moderately.  I added Jardiance and I was much better.  I stopped the metformin and relapsed and when I added it back, I regained remission.  I think metformin and Jardiance helped my colitis because they reduce inflammation in the gut.  Metformin is known to favorably modulate the gut microbiome and reduce inflammatory cytokines.  Similarly, emerging evidence supports the anti-inflammatory properties of SGLT2 inhibitors like Jardiance.  Once I was on both, the diarrhea stopped completely, even though nothing else ever worked long-term.  There is a Facebook group that can be very informative and helpful.  Look for "Microscopic Colitis and Lymphocytic Colitis Support Group.  You will find that members of the Facebook group identify other pathways to remission of microscopic colitis.
    • knitty kitty
      Cartilage and rib pain.

      By knitty kitty · Posted

      Hello, @Mrs Wolfe, I crushed three vertebrae moving a chest of drawers.  I take a combination of Thiamine Vitamin B1, Vitamin B12, and Pyridoxine B6.  Together these vitamins have an analgesic effect.  I think it works better than OTC pain relievers.   I also like  "Takeda ALINAMIN EX Plus Vitamin B1 B6 B12 Health Supplementary from Japan 120 Tablets" .   It's all three vitamins together in one pill.  Works wonderfully!
    • knitty kitty
      Progesterone pills - are they gluten free??

      By knitty kitty · Posted

      It's the Potassium Iodide in the HRT pills that is triggering Dermatitis Herpetiformis and the increased IGG levels.   The thyroid is stimulated by the Potassium Iodide, which stimulates immune cells to make more IGG antibodies.   Thiamine Vitamin B1 helps the thyroid function.  I like Benfotiamine and TTFD Thiamax.  
    • Mettedkny
      Progesterone pills - are they gluten free??

      By Mettedkny · Posted

      @Scott Adams Xiromed is one of the generic manufacturers of Progesterone pills.
    • Scott Adams
      Lymphocytic Colitis with Celiac

      By Scott Adams · Posted

      The topic has come up in the forum a lot: https://www.celiac.com/search/?q=lymphocytic colitis&quick=1&type=forums_topic and here are discussions with "colitis": https://www.celiac.com/search/?&q=colitis&type=forums_topic&quick=1&search_and_or=and&sortby=relevancy
×
×
  • Create New...