Enzyme To Battle Hidden Gluten

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The part which makes this sound realistic I bolded...

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Enzyme Could Help Celiac Disease Patients Tolerate Gluten

06.28.06, 12:00 AM ET

WEDNESDAY, June 28 (HealthDay News) -- Patients with celiac disease have to carefully monitor their diet to avoid consuming gluten, a ubiquitous protein found in whole grains.

Now, researchers say a newly discovered enzyme may prevent an allergic reaction in celiac patients who have accidentally consumed gluten.

Gluten causes an inflammatory reaction that can lead to significant intestinal damage in people suffering from celiac disease. The damage prevents the intestine from properly absorbing nutrients from food. Avoiding gluten in the diet prevents this damage, but the risk of accidentally ingesting gluten remains high.

However, researchers at Stanford University say they've identified an enzyme called EP-B2 that successfully digested gluten in an acidic environment similar to that of a human stomach. The enzyme even broke down the elements of the protein associated with causing the inflammatory reactions in celiac patients.

"Non-dietary therapies that allow celiac patients to safely incorporate low-to-moderate levels of gluten into their daily diet would be of considerable benefit," study author Dr. Chaitan Khosla, of Stanford University and the Celiac Sprue Research Foundation, said in a prepared statement. "Having demonstrated earlier that certain types of enzymes can detoxify gluten, our laboratory set out to devise an optimal oral enzyme therapy for celiac sprue by borrowing from nature," Khosla said.

"In germinating barley seed, gluten serves as a nutritious storage protein that is efficiently digested by enzymes. One enzyme, EP-B2, plays a crucial role in this process by breaking gluten proteins after glutamine residues, which comprise one-third of all amino acid residues in gluten," Khosla added.

Khosla's team used a combination of EP-B2 and PEP, another enzyme known to digest gluten. The two enzymes together broke down and detoxified gluten within 10 minutes. Neither was effective when used alone.

"Our results suggest that recombinant EP-B2 should be effective as supportive therapy to help celiacs cope with the 'hidden' gluten in everyday life, and that a two-enzyme cocktail containing PEP and EP-B2 may even allow celiacs to resume a more normal diet in the future," concluded Khosla.

[mommida]

I have been reading about this. Seems like it is being realistic.

So the big question is which of the pharma co.'s are going to be manufacturing it. Time to buy some stock.

L.

[Nantzie]

Excellent plan mommida!

Nancy

[hez]

I am one of those celiacs that really is hopeful something like this will happen in the next 10 years. I have no problem eating gluten-free, I actully like it. I find hidden gluten and cc issues when eating out extrememly frustrating. I would be so happy to have something like this to help make my social life feel more normal. Keeping my fingers crossed.

Hez

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I am one of those celiacs that really is hopeful something like this will happen in the next 10 years. I have no problem eating gluten-free, I actully like it. I find hidden gluten and cc issues when eating out extrememly frustrating. I would be so happy to have something like this to help make my social life feel more normal. Keeping my fingers crossed.

Hez

Yes this is my thoughts too

[ms-sillyak-screwed]

Where can we find EP-B2 and PEP enzymes?

Can a compound RX get it?

Quite a few on this site are doing enzyme treatment. I wonder what they know about these?

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[bluejeangirl]

Thats so exciting! I'm signed up.

gail

[penguin]

I've read that it will be late 2007 or early 2008 before it's available.

[chrissy]

if this enzyme is combined with the medication to regulate zonulin-----this could possibly make eating for a celiac almost normal.