Enterolab Results For My Daughter

[aprilh]

I got my enterolab results for my daughter who is 6. She has:

fecal antigliadin IGA 74 (normal range <10 unitsl)

Fecal antitissue transglutaminase IGA 35 units (<10 normal range)

fecal anti-casein iga antibody 50 units (normal <10)

HLA-DQB1

HLA-DQB1

(copies of gene from both parents)

serologic equivalent : HLA-DQ 3,1 subtype

Does anyone have experience with this? I understand the fecal antigliadin. But the anitissue transglutaminase I don't get. Says something about having an auto-immune reaction to the human enzyme tissue transglutaminase, secondary to gluten sensitivity

Also, I am thinking she needs to be gluten free all though she does not have very many symptoms. But for future health. Does anyone agree or disagree? The only wierd symptom she has is severe pain in her joints that come and go. I noticed when I put my 2 year old son on gluten free recently and she was gluten free just from eating what we eat, the pain went away. Then I let her start eating it again and it came back. It's a come and go thing, so I can't prove it but its mother's intuition. I know gluten can cause the strangest things in people.

The only other sort of symptom is just being a bit more tired than most kids her age. Also, seemed like she had some trouble concentrating at times. Lately she has been VERY emotional.

I really think she should be gluten free.

[Guhlia]

Those test results indicate that she should definitely be 100% gluten free for life. It's good that you discovered this so early. Have you and her father both been tested for Celiac? It sounds like either or both of you could also have Celiac.

[AndreaB]

From what I understand about the ttg is that it is other autoimmune reactions aside from gluten sensitivity.

Your daughter needs to be gluten and casein free according to her results from enterolab. Both of these are for life. She has the dq1 gene which is the one that is associated with neurological problems. What were the subtypes....was she dq3 type 7 or 8?

Your son would probably benefit by going gluten free also. You may want to have him tested as well.

Your daughters symtpoms are significant to the effect of gluten on her body. From what others have posted their children have been much happier mood wise when gluten free. The pain should also go away.

I know this could seem hard to begin with, but you have her age to your advantage. She will grow up not being used to eating gluten and dairy. It will be much easier to transition at a younger age.

[aprilh]

I discovered me all by myself. The dr's couldn't figure out what was wrong because my symptoms were so out of norm. My aunt is celiac and when I made the connection (not by her - she thinks you have to have diarreah!) and went researching on this site mostly, it clicked. I immediately went gluten-free. That is when it also clicked about my son who is 2. I discovered on this site - enterolab and ordered the test. He was positive. I did not order the gene testing on him because I KNEW this is what it was. With my daughter I knew I would have to prove something in order to get the support from hubby and family so I did the gene analysis. My husband who hasn't always been supportive or even understanding what this is, finally said, "hmmmm, wonder if I should get tested too?" He has asthma, lots of joint issues, some gastro issues. His dad has had his colon removed and his grandma has 2-3 autoimmune things going on at once right now. I knew it was on his side. I just didn't know if my little girl got it.

From what I understand about the ttg is that it is other autoimmune reactions aside from gluten sensitivity.

Your daughter needs to be gluten and casein free according to her results from enterolab. Both of these are for life. She has the dq1 gene which is the one that is associated with neurological problems. What were the subtypes....was she dq3 type 7 or 8?

Your son would probably benefit by going gluten free also. You may want to have him tested as well.

Your daughters symtpoms are significant to the effect of gluten on her body. From what others have posted their children have been much happier mood wise when gluten free. The pain should also go away.

I know this could seem hard to begin with, but you have her age to your advantage. She will grow up not being used to eating gluten and dairy. It will be much easier to transition at a younger age.

DQ3,1 Subtype 7,6. Do you mean she could be having another auto-immune reaction other than gluten and dairy? Those are the only 2 I had tested for besides the genes.

[AndreaB]

I don't understand alot about the auto immune reactions. I'm thinking other food intolerances, diabetes, etc. You may want to post a new thread about what elevated ttg means in regards to auto immune reactions. There are a lot more knowledgable people on here.

[Guest Kathy Ann]

DQ1,6 is heavily associated with neurological and psychological symptoms and damage from celiac as opposed to just the gastrointestinal kind. That might explain the emotional issues. I'm so happy that you are finding this out so young. It's so much better than when you are older. If it were me, I would certainly be going gluten free. No question.

I believe the antitissue transglutaminase test does involve another autoimmune reaction. But I think it acts as another confirmation to the presence of active gluten sensitivity. It just supports the probability that damage is actually being done.

[celiacgirls]

My daughter's tiredness and moodiness went away when she went gluten-free/CF. My other daughter and I are less easily distracted since starting this diet. So I think there's a good chance, it will help your daughter, too.

My girls both have elevated antitissue transglutaminase. I am thinking it means there is more of a chance of other problems (like diabetes, MS, fibro, lupus, etc.) developing if they were to continue eating gluten.

[Nancym]

DQ1 seems to be associated with neurological (aka brain) effects of gluten. I bet that tiredness will go away if you get her off it.