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DVjorge

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DVjorge Apprentice

Hi everybody,

I got the result of my biopsia which came back with only gastritis and h. pylori positive. When they ran the endoscopy to me, I was told my intestinal villi is atrophed. I have pseudodiarrhea, bad absorption and feel tired. I don't know if the biopsia can be reliable by itself or it is good idea to ask for blood antibody tests to exclude Celiac. Please, any advice is welcome. I am glad my biopsia didn't show celiac, but I don't feel good, and I want to be sure isn't gluten intolerance. Do you think a negative biopsia rule out the disease?

Thanks,

george.


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lizard00 Enthusiast

Did they offer you a reason as to why your villi was atrophied? While the biopsy is considered the gold standard, it can miss damage, or can be read incorrectly. Having the blood tests may help you, but they cannot rule out celiac, as they can be unreliable, too.

LDJofDenver Apprentice
Hi everybody,

I got the result of my biopsia which came back with only gastritis and h. pylori positive. When they ran the endoscopy to me, I was told my intestinal villi is atrophed. I have pseudodiarrhea, bad absorption and feel tired. I don't know if the biopsia can be reliable by itself or it is good idea to ask for blood antibody tests to exclude Celiac. Please, any advice is welcome. I am glad my biopsia didn't show celiac, but I don't feel good, and I want to be sure isn't gluten intolerance. Do you think a negative biopsia rule out the disease?

Thanks,

george.

Hmmm. Who told you the biopsy did not show signs of celiac? Typically, atrophied intestinal villi are an indicator of celiac disease. My GI doc said my small bowel biopsy showed flattened villi which, she said, confirmed the Celiac Disease. Perhaps pick up your pathology report and get a second opinion at another G.I. doc?

Yes, sometimes even if you have it blood work comes back negative but you might want to do it anyway. (mine was positive) There are also genetic tests to determine (and rule out) your chances of being susceptible to celiac disease.

nora-n Rookie

back some years ago they did not diagnose celiac unless the villi were all gone.....

Your report sasy something like that, and does sound like celiac!

Nowadays you only need slightly flattened villi, or increased intraepithelial lymphcytes.

By the way, how many IEL's were at each villi tip? They have to count them and write that in the report.

read the food doc's blog www.thefooddoc.com , you have to surf around there until you find his blog.

nora

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    • trents
      So the tTG-IGA at 28 is positive for celiac disease. There are some other medical conditions that can cause elevated tTG-IGA but this is unlikely. There are some people for whom the dairy protein casein can cause this but by far the most likely cause is celiac disease. Especially when your small bowel lining is "scalloped". Your Serum IGA 01 (aka, "total IGA") at 245 mg/dl is within normal range, indicating you are not IGA deficient. But I also think it would be wise to take your doctor's advice about the sucraid diet and avoiding dairy . . . at least until you experience healing and your gut has had a chance to heal, which can take around two years. After that, you can experiment with adding dairy back in and monitor symptoms. By the way, if you want the protein afforded by dairy but need to avoid casein, you can do so with whey protein powder. Whey is the other major protein in dairy.
    • jenniber
      hi, i want to say thank you to you and @trents   . after 2 phone calls to my GI, her office called me back to tell me that a blood test was “unnecessary” and that we should “follow the gold standard” and since my biopsy did not indicate celiac, to follow the no dairy and sucraid diet. i luckily have expendable income and made an appt for the labcorp blood test that day. i just got my results back and it indicates celiac disease i think 😭   im honestly happy bc now i KNOW and i can go gluten free. and i am SO MAD at this doctor for dismissing me for a simple blood test that wouldn’t have cost her anything !!!!!!!!!!! im sorry, im so emotional right now, i have been sick my whole life and never knew why, i feel so much better already   my results from labcorp:   Celiac Ab tTG TIgA w/Rflx Test Current Result and Flag Previous Result and Date Units Reference Interval t-Transglutaminase (tTG) IgA 01 28 High U/mL 0-3 Negative 0 - 3 Weak Positive 4 - 10 Positive >10 Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy. Immunoglobulin A, Qn, Serum 01 245 mg/dL 87-352
    • JoJo0611
      Thank you this really helped. 
    • Samanthaeileen1
      Okay that is really good to know. So with that being positive and the other being high it makes sense she diagnosed her even without the endoscopy. So glad we caught it early. She had so many symptoms though that to me it was clear something was wrong.   yeah I think we had better test us and the other kids as well. 
    • GlorietaKaro
      One doctor suggested it, but then seemed irritated when I asked follow-up questions. Oh well—
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