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The Flu As A Trigger?


flutterby

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flutterby Apprentice

I have heard several people mention that their Celiac manifested itself 'after getting the flu'. This was my case ... I had been having problems for months, but it wasn't until after I had a 3-Day fever/flu that I got so sick I was eventually diagnosed with gluten intolerance.

Could this be the Flu acting as a trigger? Or could a high fever/flu-like symptoms be part of the body's autoimmune response at its peak?


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ElseB Contributor

Any kind of major stress can be the trigger. For me, the major trigger that led to diagnosis was getting c.difficile and then not getting better after the c.diff was clear. But looking back, I think the real start of symptoms was the first marathon I ran. So any kind of stress - illness, physical stress (marathon!), emotional stress, etc.

psawyer Proficient

HelpMe is right. Anything that puts a stress on the immune system can be a trigger to activate celiac disease. Flu and mononucleosis are commonly reported, as is childbirth. Emotional stress, such as loss of a job, death of a loved one, or breakdown of a marriage have also been reported as triggers.

Kay DH Apprentice

My celiac symptoms started 13 months ago. I caught the flu and was sick for about 3 days. A few days later I was back to commuting to work on my mountain bike, and a very stressful event happened on my ride home. I was biking 35 mph in the bike lane and some people threw a 6 lb rock at me. It missed me because I was braking hard (love those hydraulic brakes). The police said it would only have been a misdemeanor had they caught them. A week or two later the GI, brain fog, stiff joints, muscle aches, and aching feet started. So, my gluten problems seemed to kick in with the virus and stress. I went gluten-free soon after this, and the celiac panel a few months later (while gluten-free) was negative. The 1 endoscopy biopsy was negative 6 months later (GI had me 1 week on a gluten challenge). I have HLA-DQ8 and no symptoms while gluten-free, but now very sensitive to cc. I am 56; the symptoms can start at any age. ;)

Skylark Collaborator

Flu made me much worse. That's when the gluten started really affecting my mind as well as my GI system.

jerseyangel Proficient

I had a bout with the flu in late 2003 that without a doubt kicked my Celiac into high gear. I was never the same after that.

Kay DH Apprentice

I was talking with a friend yesterday whose SIL got the flu, followed by Lupus. I suggested she mention the gluten-free diet to her SIL, in case she was sensitive to the proteins and abstinence helped the Lupus symptoms.


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    • Scott Adams
      If your tTg-IgA was 28 and positive is at 3, you are nearly 10x over the positive marker, so the most likely explanation by far would be celiac disease. I also do not understand why your doctor would not want to run the blood test, which is the normal first step in the diagnosis process.
    • xxnonamexx
      Is there a digestive enzyme that helps build a healthier gut? I see people taking them but not sure what really works
    • trents
      So the tTG-IGA at 28 is positive for celiac disease. There are some other medical conditions that can cause elevated tTG-IGA but this is unlikely. There are some people for whom the dairy protein casein can cause this but by far the most likely cause is celiac disease. Especially when your small bowel lining is "scalloped". Your Serum IGA 01 (aka, "total IGA") at 245 mg/dl is within normal range, indicating you are not IGA deficient. But I also think it would be wise to take your doctor's advice about the sucraid diet and avoiding dairy . . . at least until you experience healing and your gut has had a chance to heal, which can take around two years. After that, you can experiment with adding dairy back in and monitor symptoms. By the way, if you want the protein afforded by dairy but need to avoid casein, you can do so with whey protein powder. Whey is the other major protein in dairy.
    • jenniber
      hi, i want to say thank you to you and @trents   . after 2 phone calls to my GI, her office called me back to tell me that a blood test was “unnecessary” and that we should “follow the gold standard” and since my biopsy did not indicate celiac, to follow the no dairy and sucraid diet. i luckily have expendable income and made an appt for the labcorp blood test that day. i just got my results back and it indicates celiac disease i think 😭   im honestly happy bc now i KNOW and i can go gluten free. and i am SO MAD at this doctor for dismissing me for a simple blood test that wouldn’t have cost her anything !!!!!!!!!!! im sorry, im so emotional right now, i have been sick my whole life and never knew why, i feel so much better already   my results from labcorp:   Celiac Ab tTG TIgA w/Rflx Test Current Result and Flag Previous Result and Date Units Reference Interval t-Transglutaminase (tTG) IgA 01 28 High U/mL 0-3 Negative 0 - 3 Weak Positive 4 - 10 Positive >10 Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy. Immunoglobulin A, Qn, Serum 01 245 mg/dL 87-352
    • JoJo0611
      Thank you this really helped. 
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