Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Two Test Questions---Any Help Please?


coryjmclaughlin

Recommended Posts

coryjmclaughlin Newbie

I've had severe diahrea since March and have had a colonscopy and been put on antibiotics, Librax and Nexium. Nothing has worked. I also have Lupus and recently had my prednisone increased which slightly helped my diahrea but now that I am tapering down the diahrea is back again. My GI doctor says I need to just live with it as everything is "normal" so I decided to go for a second opinion. I picked up my records today and two things made me a little uneasy. My fecal fat test was Positive and my IgA serum was low at 73. Could either of this be indicative of Celiac's? I also get bloating and very uncomfortable after eating.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



sb2178 Enthusiast

It could. Keep in mind that you need to be eating a full gluten diet for any testing to be valid (3-4 slices bread or equivalent per day).

Testing is generally a good idea if you have access; just make sure you go in with a list of the full panel. Often, they'll only run one or two tests on the panel and it sounds like you need to have the IgG versions of the tests run. If you have IgA levels below normal, the most common celiac tests are not valid. If your tests are positive, equivocal, or your MD thinks you likely have it, you may be referred for an endoscopy (through the mouth to the intestines).

I don't know how or if prednisone would affect any testing.

After you are done with testing, you can also try a strict elimination diet to see if that helps your symptoms. Read and ask questions!

beachbirdie Contributor

I've had severe diahrea since March and have had a colonscopy and been put on antibiotics, Librax and Nexium. Nothing has worked. I also have Lupus and recently had my prednisone increased which slightly helped my diahrea but now that I am tapering down the diahrea is back again. My GI doctor says I need to just live with it as everything is "normal" so I decided to go for a second opinion. I picked up my records today and two things made me a little uneasy. My fecal fat test was Positive and my IgA serum was low at 73. Could either of this be indicative of Celiac's? I also get bloating and very uncomfortable after eating.

You have lupus. There is a genetic connection between that and other autoimmune conditions like autoimmune thyroid (Grave's and Hashimoto's) and celiac.

I would see about getting genetic test and endoscopic biopsy done, it is in the realm of possibility that you have a gluten issue. You do need to have been eating gluten for a while to get a "real" result. If they just do blood tests, you might get a skewed result as your IgA is low. Is there a possibility you could see a different GI? Do you have anyone in your family with gluten or other autoimmune conditions?

I am a Hashimoto's sufferer myself, I am making the choice to go gluten free. I think if I had lupus I would do the same. After testing you can try the gluten free diet and see if you feel better.

Best,

beachbirdie

coryjmclaughlin Newbie

You have lupus. There is a genetic connection between that and other autoimmune conditions like autoimmune thyroid (Grave's and Hashimoto's) and celiac.

I would see about getting genetic test and endoscopic biopsy done, it is in the realm of possibility that you have a gluten issue. You do need to have been eating gluten for a while to get a "real" result. If they just do blood tests, you might get a skewed result as your IgA is low. Is there a possibility you could see a different GI? Do you have anyone in your family with gluten or other autoimmune conditions?

I am a Hashimoto's sufferer myself, I am making the choice to go gluten free. I think if I had lupus I would do the same. After testing you can try the gluten free diet and see if you feel better.

Best,

beachbirdie

Thanks for the info. I am seeing a new GI doctor on Friday afternoon. My colonscopy biopsy stuff also showed "chronic mucosal injury". I have been eating as normally as I can which means I haven't been limiting any food so I should have enough gluten in me.

mushroom Proficient

If you have a low serum IgA then any IgA testing for celiac disease would be invalid. Keep up the gluten and hope that your new GI is clued in to celiac. :)

Good luck on Friday.

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,663
    • Most Online (within 30 mins)
      7,748

    Funnybone
    Newest Member
    Funnybone
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Inkie
      Thank you for the information ill will definitely bring it into practice .
    • Scott Adams
      While plain, pure tea leaves (black, green, or white) are naturally gluten-free, the issue often lies not with the tea itself but with other ingredients or processing. Many flavored teas use barley malt or other gluten-containing grains as a flavoring agent, which would be clearly listed on the ingredient label. Cross-contamination is another possibility, either in the facility where the tea is processed or, surprisingly, from the tea bag material itself—some tea bags are sealed with a wheat-based glue. Furthermore, it's important to consider that your reaction could be to other substances in tea, such as high levels of tannins, which can be hard on the stomach, or to natural histamines or other compounds that can cause a non-celiac immune response. The best way to investigate is to carefully read labels for hidden ingredients, try switching to a certified gluten-free tea brand that uses whole leaf or pyramid-style bags, and see if the reaction persists.
    • Scott Adams
      This is a challenging and confusing situation. The combination of a positive EMA—which is a highly specific marker rarely yielding false positives—alongside strongly elevated TTG on two separate occasions, years apart, is profoundly suggestive of celiac disease, even in the absence of biopsy damage. This pattern strongly aligns with what is known as "potential celiac disease," where the immune system is clearly activated, but intestinal damage has not yet become visible under the microscope. Your concern about the long-term risk of continued gluten consumption is valid, especially given your family's experience with the consequences of delayed diagnosis. Since your daughter is now at an age where her buy-in is essential for a gluten-free lifestyle, obtaining a definitive answer is crucial for her long-term adherence and health. Given that she is asymptomatic yet serologically positive, a third biopsy now, after a proper 12-week challenge, offers the best chance to capture any microscopic damage that may have developed, providing the concrete evidence needed to justify the dietary change. This isn't about wanting her to have celiac; it's about wanting to prevent the insidious damage that can occur while waiting for symptoms to appear, and ultimately giving her the unambiguous "why" she needs to accept and commit to the necessary treatment. This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. One test that always needs to be done is the IgA Levels/Deficiency Test (often called "Total IGA") because some people are naturally IGA deficient, and if this is the case, then certain blood tests for celiac disease might be false-negative, and other types of tests need to be done to make an accurate diagnosis. The article includes the "Mayo Clinic Protocol," which is the best overall protocol for results to be ~98% accurate.    
    • Scott Adams
      Welcome to the community! Generally, for a gluten challenge before celiac disease blood tests, Tylenol (acetaminophen) is considered safe and should not interfere with your antibody results. The medications you typically need to avoid are those like ibuprofen (Advil, Motrin) or naproxen (Aleve) that can cause intestinal irritation, which could potentially complicate the interpretation of an endoscopy if you were to have one. However, it is absolutely crucial that you confirm this with either your gastroenterologist or your surgeon before your procedure. They know the specifics of your case and can give you the definitive green light, ensuring your surgery is comfortable and your celiac testing remains accurate. Best of luck with your surgery tomorrow
    • Xravith
      Thank you for the advice. I’ve actually never checked for nutritional deficiencies, but for as long as I can remember, I’ve always taken vitamin and mineral supplements — otherwise my symptoms get worse. This week I stopped eating gluten to confirm whether my symptoms are really caused by it. Starting next week, I’ll reintroduce gluten — it’s sad to go back to how I was before — but at least I’ll be able to take the necessary tests properly. I think the diagnostic process will be long, but at least I’m happy that I finally decided to address this doubt I’ve had for years.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.