celiac disease Associated Autoantibodies In Dh Published 4/12

[squirmingitch]

I know this is some really important info. for us & may give those of us with dh a better chance for testing & dx. I'm not that great at understanding EXACTLY how much hope this gives us though. Some of you have a better grasp of medical techno lingo &/or may be able to access the entire article. Would like comments on this.

Open Original Shared Link

Novel assay for detecting celiac disease-associated autoantibodies in dermatitis herpetiformis using deamidated gliadin-analogous fusion peptides.

Open Original Shared Link, [url=Open Original Shared Link

[pricklypear1971]

I can't being anything intelligent to the discussion but what is the GAF3x?

[squirmingitch]

I think it's this:

deamidated gliadin-analogous fusion

peptides

(GAF3X)

see:

https://www.celiac.com/articles/21901/1/Antibodies-to-Deamidated-Gliadin-as-a-Tool-in-Diagnosing-Childhood-Celiac-Disease/Page1.html

[pricklypear1971]

Hmm. I looked on the LabCorp site and don't see it - or don't think I see it. I wonder which labs offer it.

[squirmingitch]

This is also what they say is better for detecting celiac in children.

Open Original Shared Link

[pricklypear1971]

Yes, but how do you GET it?

[squirmingitch]

I haven't the foggiest notion. I did a search too for Labs who do it & couldn't get anywhere --- just kept coming up with the article abstract.

Ask doctors?

[ciamarie]

Dunno. But it does look promising, as far as a tool for detecting DH / celiac without biopsy!

[itchy]

I took it to mean that in tests (done correctly) the false negative level will be 30%. Or possibly the false positive rate. In any case it appears that the tests will be slightly better and there are at least eight researchers working on improving them. THat's good news to me.