Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

What's The Science Behind Celiac Soy Intolerance?

Chakra2

By Chakra2
in Coping with Celiac Disease

Recommended Posts

Chakra2 Contributor
Chakra2
Posted

I have read about why some celiacs have trouble digesting dairy at first -- you need the lactase from the tips of the villi. But why are so many gluten-sensitive people also bothered by soy?Is there a similar anatomically-based reason?

Also, I'd love to know if/when/how anyone was able to reintroduce soy. I was vegetarian for 19 years (now pescatarian) so I did learn to love my miso and my tofu! And wheat-free soy sauce would be a big treat now that it looks like I'll be eating a lot of rice from here on out. :)

I'm curious about a dairy issue, too. Are all lactose-intolerant (non-celiac/non-gluten sensitive) folks out there missing the tips of their villi? Or are there other reasons that "normal" people become lactose intolerant?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Jestgar Rising Star
Jestgar
Posted

Soy is a big, giant, hard-to-digest protein, as is casein. It may be that a lot of people don't digest it well, but don't get enough symptoms to be bothered by it.

Many adults are lactose intolerant. You are designed to consume milk only as an infant, it's a recent mutation that allows the lactase enzyme to persist in adults.

GlutenFreeManna Rising Star
GlutenFreeManna
Posted

I don't have any science (sorry) but I read on some natural medicine sites that there was a connection between soy and thyroid disease. Hypothyroidism runs in my family so I cut out soy when I first did my elimination diet. When I tried to add it back in I had fatigue, joint swelling, muscle pain and extreme moodiness. So even though my thyroid tests are still coming back as normal, I'm inclined to think from my own personal testing that soy messes with my thyroid. Like I said I don't have any hard science to back this up, but if you do a search you will find all kinds of sites warning about giving infants soy formula. Perhaps that could be a starting place for you to find some scientific articles.

Marz Enthusiast
Marz
Posted

Well if certain gene mutations cause the body to produce antibodies in response to gluten, when not soy? Especially if they're similar structures.

I'm wondering if there are some "soy" celiacs out there that are being missed because their body is producing antibodies to soy, and not gluten? Maybe that's why lots of blood tests are false negative - we're just not looking for the specific antibody that some of us are producing? Just speculating at this point, because I have no scientific basis for any of this :)

I do know I react in *exactly* the same way to soy as I do to gluten, both immediately and days later.

Skylark Collaborator
Skylark
Posted

With the gluten and dairy, some celiacs' anti-gliadin antibodies recognize casein. This doesn't happen in all celiacs, so there are some negative studies around as well.

Open Original Shared Link

Open Original Shared Link

There was also an interesting study on biopsied mucosa where damaged mucosa could not break down casein. Bigger fragments of food protein are more immunologically active.

Open Original Shared Link

Celiacs have more anti-casein and anti-soy antibodies in general.

Open Original Shared Link

Open Original Shared Link

If you piece things together, you can hypothesize that celiacs have a combination of more antibodies in general and poor digestion. Bits of undigested food might react with all the antibodies so you get a soy or casein reaction in unhealed celiacs.

By the way, it took me between six and nine months to reintroduce casein and soy.

kwylee Apprentice
kwylee
Posted

With the gluten and dairy, some celiacs' anti-gliadin antibodies recognize casein. This doesn't happen in all celiacs, so there are some negative studies around as well.

Open Original Shared Link

Open Original Shared Link

There was also an interesting study on biopsied mucosa where damaged mucosa could not break down casein. Bigger fragments of food protein are more immunologically active.

Open Original Shared Link

Celiacs have more anti-casein and anti-soy antibodies in general.

Open Original Shared Link

Open Original Shared Link

If you piece things together, you can hypothesize that celiacs have a combination of more antibodies in general and poor digestion. Bits of undigested food might react with all the antibodies so you get a soy or casein reaction in unhealed celiacs.

By the way, it took me between six and nine months to reintroduce casein and soy.

This info is so helpful!!! And thanks so much for the synopsis of the links in everyday speak! Appreciate that!

Skylark Collaborator
Skylark
Posted

This info is so helpful!!! And thanks so much for the synopsis of the links in everyday speak! Appreciate that!

Summarizing links was Jestgar's excellent advice. :) Glad it helps and you found the info useful.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


tweeks2010 Apprentice
tweeks2010
Posted

Today I tested myself with the ingredient soy lecithin i about 5 different things I ate today. Guess what...I get the same symptoms with that as I do when I get glutened. I only did a somewhat small amount , but it was enough to give me stomach cramping that has so far lasted hours and is still going.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Wheatwacked
      - Wheatwacked replied to Jane02's topic in Gluten-Free Foods, Products, Shopping & Medications
      22

      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      That is the goal, after all.
    2. Wheatwacked
      - Wheatwacked replied to Heatherisle's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      34

      Blood results

      Celiac Disease causes more vitamin D deficiency than the general population because of limited UV sunlight in the winter and the little available from food is not absorbed well in the damaged small intestine. Taking 10,000 IU a day (250 mcg) a day broke my depression. Taking it for eleven years. Doctor recently said to not stop. My 25(OH)D is around 2...
    3. Known1
      - Known1 replied to xxnonamexx's topic in Gluten-Free Foods, Products, Shopping & Medications
      6

      FDA looking for input on Celiac Gluten sensitivity labeling PLEASE READ and submit your suggestions

      Thank you for sharing your thoughts. I respectfully disagree. You cherry picked a small section from the page. I will do the same below: The agency is seeking information on adverse reactions due to “ingredients of interest” (i.e., non-wheat gluten containing grains (GCGs) which are rye and barley, and oats due to cross-contact with GCGs) and on ...
    4. Wheatwacked
      - Wheatwacked replied to catnapt's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      31

      results from 13 day gluten challenge - does this mean I can't have celiac?

      Here is a link to the spreadsheet I kept to track my nutrition intakes. Maybe it will give you ideas. It is not https so browsers may flag a security warning. There is nothing to send or receive. http://doodlesnotes.net/index3.html I tracked everything I ate, used the National Nutrition Database https://www.foodrisk.org/resources/display/...
    5. Wheatwacked
      - Wheatwacked replied to catnapt's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      31

      results from 13 day gluten challenge - does this mean I can't have celiac?

      Hello @catnapt, That's so true. Every person with Celiac Disease has different symptoms. There are over 200 that it mimics. Too many still believe that it is only a childhood disease you outgrow. Or it's psychosomatic or simply a fad. Idiots. It's easy to get angry at all of them. You just have to pick at the answers until you find...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,414
    • Most Online (within 30 mins)
      7,748
    EBeloved
    Newest Member
    EBeloved
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • Wheatwacked
      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      By Wheatwacked · Posted

      That is the goal, after all.  
    • Wheatwacked
      Blood results

      By Wheatwacked · Posted

      Celiac Disease causes more vitamin D deficiency than the general population because of limited UV sunlight in the winter and the little available from food is not absorbed well in the damaged small intestine.  Taking 10,000 IU a day (250 mcg) a day broke my depression. Taking it for eleven years.  Doctor recently said to not stop.  My 25(OH)D is around 200 nmol/L (80 ng/ml) but it took about six years to get there.  Increasing vitamin D also increases absorption of Calcium. A good start is 100-gram (3.5-ounce) serving of salmon,  vitamin D from 7.5 to 25 mcg (300 to 1,000 IU) but it is going to take additional vitamin D supplement to be effective.  More importantly salmon has an omega-6 to omega-3 ratio 1:10 anti-inflammatory compared to the 15:1 infammatory ratio of the typical Western diet. Vitamin D and Depression: Where is all the Sunshine?
    • Known1
      FDA looking for input on Celiac Gluten sensitivity labeling PLEASE READ and submit your suggestions

      By Known1 · Posted

      Thank you for sharing your thoughts.  I respectfully disagree.  You cherry picked a small section from the page.  I will do the same below: The agency is seeking information on adverse reactions due to “ingredients of interest” (i.e., non-wheat gluten containing grains (GCGs) which are rye and barley, and oats due to cross-contact with GCGs) and on labeling issues or concerns with identifying these “ingredients of interest” on packaged food products in the U.S. “People with celiac disease or gluten sensitives have had to tiptoe around food, and are often forced to guess about their food options,” said FDA Commissioner Marty Makary, M.D., M.P.H. “We encourage all stakeholders to share their experiences and data to help us develop policies that will better protect Americans and support healthy food choices.” --- end quote Anyone with celiac disease is clearly a stakeholder.  The FDA is encouraging us to share our experiences along with any data to help develop future "policies that will better protect Americans and support healthy food choices".  I see this as our chance to speak up or forever hold our peace.  Like those that do not participate in elections, they are not allowed to complain.  The way I see it, if we do not participate in this request for public comment/feedback, then we should also not complain when we get ill from something labeled gluten-free. Have a blessed day ahead, Known1
    • Wheatwacked
      results from 13 day gluten challenge - does this mean I can't have celiac?

      By Wheatwacked · Posted

      Here is a link to the spreadsheet I kept to track my nutrition intakes.  Maybe it will give you ideas. It is not https so browsers may flag a security warning. There is nothing to send or receive. http://doodlesnotes.net/index3.html I tracked everything I ate, used the National Nutrition Database https://www.foodrisk.org/resources/display/41 to add up my daily intake and supplemented appropriately.  It tracks about 30 nutrients at once.
    • Wheatwacked
      results from 13 day gluten challenge - does this mean I can't have celiac?

      By Wheatwacked · Posted

      Hello @catnapt, That's so true.  Every person with Celiac Disease has different symptoms.  There are over 200 that it mimics.  Too many still believe that it is only a childhood disease you outgrow.  Or it's psychosomatic or simply a fad.  Idiots.  It's easy to get angry at all of them.   You just have to pick at the answers until you find the ones that work for you.  I too suffer from not being able to take the drugs that work for "everyone else".  SSRIs make me twitch ane feel like toothpicks are holding my eye open, ARBs cripple me.  Statins cause me intestinal Psuedo Obstruction.  Espresso puts me to sleep.  I counted 19 different symptoms that improved from GFD and dealing with my nutritional defecits.  I couldn't breath through my mouth until I started GFD at 64 years old.   My son was born with celiac disease, biopsy diagnosed at weaning.   So why are we the one-percenters.  Why, after being silent for so long, does it suddenly flare? There is the possibility that you have both Celiac Disease and Non Celiac Gluten Sensitivity.  NCGS was not established as a diagnosis until 1980.  NCGS is diagnost by first elimating Celiac Disease as the cause, and showing improvement on GFD.  Nothing says you can't have symptoms from both.  Wheatbelly: Total Nutrition by Dr. Davis was helpful to me. We come to the forum to share what we've learned in dealing with our own symptoms.  Maybe this will help someone. Speaking of which if you don't mind; what is your 25(OH)D vitamin D blood level?  You mentioned a mysterious Calcium issue. Vitamin D, Calcium and Iodine are closely interactive. It is not uncommon for postmenopausal women to have insufficient intake of Iodine.   (RDA): Average daily level of intake sufficient to meet the nutrient requirements of nearly all (97%–98%) healthy individuals; often used to plan nutritionally adequate diets for individuals You are a one-percenter.  You may need higher intake of some essential nutrient supplements to speed up repairing the damages.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.