Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Anaphylaxis due to celiac disease?

Tash18

By Tash18
in Food Intolerance & Leaky Gut

 Share

Recommended Posts

Scott Adams Grand Master
Scott Adams
Posted

@Anniehall Do you realize that the article you pointed me to is critical of the existence of "cross reactive foods?" 

https://paleofoundation.com/19-gluten-cross-reactive-foods/

Quote

ABSTRACT

1. Numerous online blog articles report  ”19 Gluten Cross-Reactive foods. “

2. Close inspection reveals questionable conclusions and significant overstatement and extrapolation from the original sources of information.

3. Alternate conclusions presented within this blog article would call into question the existence of many blog-reported gluten cross-reactive foods.

4. Lessons about rigorous research and reporting of scientific data can be learned.

 

Quote

CONCLUSIONS

However, The Celiac Disease Center does not currently recognize Enterolabs or Cyrex stool tests for cross-reactivity (or for CD for that matter). [20] Simply, they are “not sensitive or specific enough” and just haven’t held water (yet) in the scientific arena.

This article mentions cross reactivity, but it does not in any way explain it, or provide any evidence to support it:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936671/

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Anniehall Enthusiast
Anniehall
Posted
2 hours ago, Scott Adams said:

@Anniehall Do you realize that the article you pointed me to is critical of the existence of "cross reactive foods?" 

https://paleofoundation.com/19-gluten-cross-reactive-foods/

 

This article mentions cross reactivity, but it does not in any way explain it, or provide any evidence to support it:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936671/

Yes. The paleobfoundation article says that only some of the foods are true cross reactives. 

Anniehall Enthusiast
Anniehall
Posted

It doesn't deny the existence of cross reactives all together. It just says that there are not actually 19 of them. Did you read the whole thing or just skip to the conclusion and make a judgment to fit with your prior thoughts on the subject?  What's strange in my case is that it took 7 months of me going gluten free for some of the cross reactives to cause skin reactions. After cutting the foods out for several months it takes between 1 and 2 months after being without them and adding them back in for me to start reacting again. Where as with gluten, Even a miniscule amount, I will react within an hour to early the next day with a skin reaction. 

Anniehall Enthusiast
Anniehall
Posted

Trents. I'm just trying to reply to the thread not quote my own posts. I'm new to this forum. I'll be more careful on that. Sorry if it annoyed you. 

Why is there no option to edit or delete your own posts on this site after a posting?

Anniehall Enthusiast
Anniehall
Posted

Oh. I know why it's looking like I'm quoting my own thread. Even when I click reply to this thread it repeats my last post often whether or not I press quote and reply. I just clicked reply to this thread and that happened and then I found an option to delete the previous quoted comment out. I don't know why it does that in the first place. You should be able to comment on a specific post in a thread without it requoting the whole thing in entirety each time. I did not design the website so don't blame me for the lack of user friendliness. I reread the paleo foundation article. The woman is mentioning that she believes some of the cross reactives may not be true cross reactives but just gluten contaminated grains and others are more likely to be cross reactives. Really though there seems to be overlap with several characteristics of these other foods that people with celiacs can react to besides gluten ( "the cross reactives"). These are off the top of my head. Many are lectins, many are plant based major protein sources, many are considered gluten cross reactives, many are even in the same food family as wheat, barley and rye,  and many have an extremely unhealthy arginine to lysine ratio when consumed in the absence of meat and dairy. I don't understand the skeptics behind the cross reactive theory. It makes sense to me. 

I thought maybe it was the arginine to lysine ratio being an issue so when I began eating again after my last fast which went on for far too long. I added them back in but made sure to always pair them with high lysine foods and lysine supplementation. This worked for about a month and a half and then the skin reactions came back shortly before the onset of my second menstruation and got worse after that eventually turning back to the worst of the skin reactions that I have, DH. 

Oh. I know why it's looking like I'm quoting my own thread. Even when I click reply to this thread it repeats my last post often whether or not I press quote and reply. I just clicked reply to this thread and that happened and then I found an option to delete the previous quoted comment out. I don't know why it does that in the first place. You should be able to comment on a specific post in a thread without it requoting the whole thing in entirety each time. I did not design the website so don't blame me for the lack of user friendliness. I reread the paleo foundation article. The woman is mentioning that she believes some of the cross reactives may not be true cross reactives but just gluten contaminated grains and others are more likely to be cross reactives. Really though there seems to be overlap with several characteristics of these other foods that people with celiacs can react to besides gluten ( "the cross reactives"). These are off the top of my head. Many are lectins, many are plant based major protein sources, many are considered gluten cross reactives, many are even in the same food family as wheat, barley and rye,  and many have an extremely unhealthy arginine to lysine ratio when consumed in the absence of meat and dairy. I don't understand the skeptics behind the cross reactive theory. It makes sense to me. 

I thought maybe it was the arginine to lysine ratio being an issue so when I began eating again after my last fast which went on for far too long. I added them back in but made sure to always pair them with high lysine foods and lysine supplementation. This worked for about a month and a half and then the skin reactions came back shortly before the onset of my second menstruation and got worse after that eventually turning back to the worst of the skin reactions that I have, DH. 

Wheatwacked Veteran
Wheatwacked
Posted
53 minutes ago, Anniehall said:

Even when I click reply to this thread it repeats my last post often whether or not I press quote and reply.

I've noticed it too. If you post another reply before someone else has, it saves your previous post. Simply remember to delete it before continuing,

Wheatwacked Veteran
Wheatwacked
Posted
7 hours ago, Anniehall said:

My immune system skin reactions really started acting up more after I got pregnant

Vitamin and mineral deficiencies, especially choline, folate and iodine are common in pregnancy. Tack that on to malabsorption due to undiagnosed celiac disease and you've got the perfect storm.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Scott Adams Grand Master
Scott Adams
Posted

ok

1 hour ago, Anniehall said:

It doesn't deny the existence of cross reactives all together. It just says that there are not actually 19 of them. Did you read the whole thing or just skip to the conclusion and make a judgment to fit with your prior thoughts on the subject?  What's strange in my case is that it took 7 months of me going gluten free for some of the cross reactives to cause skin reactions. After cutting the foods out for several months it takes between 1 and 2 months after being without them and adding them back in for me to start reacting again. Where as with gluten, Even a miniscule amount, I will react within an hour to early the next day with a skin reaction. 

I read the post, it’s not a peer-reviewed study, but does say the following, so it doesn’t really support the concept of cross-reactivity which is too often thrown around:

Observing the “p-values” reported in Table 2: Using the p ≤ 0.05 threshold, we can reject the null hypothesis for α-gliadin (outlined in blue, positive control). If we’re generous and we increase

Observing  the “p-values” reported in Table 2:

Using the p ≤ 0.05 threshold, we can reject the null hypothesis for α-gliadin (outlined in blue, positive control). If we’re generous and we increase our threshold to p ≤ 0.1 (meaning the frequency of getting results at least this large under the null hypothesis is less than or equal to 10%), we can include yeast, millet, and corn.

p = 0.5 means that there is a 50% chance of getting results at least as large as what was observed under the null hypothesis of no effect. In other words, if we repeated this experiment several times, half of the time, we’d see differences at least this big, even if there was no actual effect. 

This calls into question the interpretation of the results, because the results are so consistent with the null hypothesis of no effect. While the means of the assays (reported as a % inhibition) may have been reduced (indicating binding), there was apparently such high assay variability that it was not a significant difference from the control. Therefore, these results are consistent with the hypothesis of no effect, and consistent with the idea that the differences we see are due to chance. 

threshold to p ≤ 0.1 (meaning the frequency of getting results at least this large under the null hypothesis is less than or equal to 10%), we can include yeast, millet, and corn. p = 0.5 means that there is a 50% chance of getting results at least as large as what was observed under the null hypothesis of no effect. In other words, if we repeated this experiment several times, half of the time, we’d see differences at least this big, even if there was no actual effect. This calls into question the interpretation of the results, because the results are so consistent with the null hypothesis of no effect. While the means of the assays (reported as a % inhibition) may have been reduced (indicating binding), there was apparently such high assay variability that it was not a significant difference from the control. Therefore, these results are consistent with the hypothesis of no effect, and consistent with the idea that the differences we see are

trents Grand Master
trents
Posted
3 hours ago, Anniehall said:

Trents. I'm just trying to reply to the thread not quote my own posts. I'm new to this forum. I'll be more careful on that. Sorry if it annoyed you. 

Why is there no option to edit or delete your own posts on this site after a posting?

There is a timer on the edit function. If you wait very long the edit function is not available.

If you don't need to quote someone or yourself in the next post, scroll down past "Quote and Reply" and there will be another text entry area just below that.

Anniehall Enthusiast
Anniehall
Posted

That study is also on animals not on humans. 

Anniehall Enthusiast
Anniehall
Posted

I think people should look more closely at how plants are related to figure out their sensitivities. That seemed to be the most helpful for me in figuring out my sensitivities. I still don't necessarily think cross reactives are non existent. But I also don't think you need a college degree to be creditable nor do I ignore every anecdotal bit of info that I take in. 

knitty kitty Grand Master
knitty kitty
Posted
5 hours ago, Anniehall said:

 But I also don't think you need a college degree to be creditable nor do I ignore every anecdotal bit of info that I take in. 

 

Anniehall,

Have you ever tried removing dairy products from your diet?

Dairy, especially the protein casein, can cause all sorts of problems in the skin, including acne and ketosis pillaris.

 

Dairy Intake and Acne Vulgaris: A Systematic Review and Meta-Analysis of 78,529 Children, Adolescents, and Young Adults

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115795/

 

And...

Evidence for acne-promoting effects of milk and other insulinotropic dairy products

https://pubmed.ncbi.nlm.nih.gov/21335995/

 

And ... this could be why you seem to be reacting to so many different foods....

Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen

https://pubmed.ncbi.nlm.nih.gov/7532192/

 

And...

Mucosal reactivity to cow's milk protein in coeliac disease

https://pubmed.ncbi.nlm.nih.gov/17302893/

"A mucosal inflammatory response similar to that elicited by gluten was produced by Cow's Milk protein in about 50% of the patients with coeliac disease. Casein, in particular, seems to be involved in this reaction."

 

And...

"Casomorphins and Gliadorphins Have Diverse Systemic Effects Spanning Gut, Brain and Internal Organs"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345738/

 

Are you supplementing vitamins while you fast?  

 

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,187
    • Most Online (within 30 mins)
      7,748
    Kris46
    Newest Member
    Kris46
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Ginger38
      Food Allergies

      By Ginger38 · Posted

      So I recently had allergy testing for IGE antibodies in response to foods. My test results came back positive to corn, white potatoes, egg whites. Tomatoes, almonds and peanuts to name a few.  I have had obvious reactions to a few of these - particularly tomatoes and corn- both GI issues. I don’t really understand all this allergy versus celiac stuff. If the food allergies are mild do I have to avoid these foods entirely? I don’t know what I will eat if I can’t  have corn based gluten free products 
    • Kris2093u4
      Bread choice for a newbie

      By Kris2093u4 · Posted

      Geography makes a difference.  I'm in the West and Trader Joe's gluten-free bread tastes great and is a better price than most gluten-free breads sold elsewhere in my area.  
    • JForman
      7yo struggling!

      By JForman · Posted

      We have four children (7-14 yo), and our 7 year old was diagnosed with NCGS (though all Celiac labs were positive, her scope at 4 years old was negative so docs in the US won't call it celiac). We have started her on a Gluten Free diet after 3 years of major digestive issues and ruling out just about everything under the sun. Our home and kitchen and myself are all gluten-free. But I have not asked my husband/her dad or her other siblings to go completely gluten-free with us. They are at home, but not out of the home. This has led to situations when we are eating out where she has to consistently see others eating things she can't have and she has begun to say "Well, I can't have <fill in the blank>...stupid gluten."  How have you supported your gluten-free kiddos in the mental health space of this journey, especially young ones like her. I know it's hard for me as an adult sometimes to miss out, so I can't imagine being 7 and dealing with it! Any tips or ideas to help with this? 
    • Jane878
      My mo,ther married a bread making when I was 4

      By Jane878 · Posted

      By the time I was 5 I had my first auto0immune disorder, Migraine headaches, with auras to blind me, and vomiting, sensitivity to light and sound. I was 5 years old, and my stepfather would have pizza night, milling his own flour, making thick cheesy gluten pizza, that I would eat and the next day, I would have serious migraines, and my mother & stepfather did nothing about my medical problems. When I was 17 in my first year at college, I was diagnosed with my 2nd known auto-immune disorder, Meniere's disease. I was a elite athlete, a swimmer, and soccer player. And once again my parents didn't think anything of understanding why I had a disorder only older people get. Now after my mother passed from Alzheimer's disease she also suffered with living with gluten. She had a rash for 30 years that nobody could diagnose. She was itchy for 45 years total. My brother had a encapsulated virus explodes in his spleen and when this happened his entire intestines were covered with adhesions, scar tissue and he almost lost his life. He has 5 daughters, and when I finally was diagnosed after being pregnant and my body went into a cytokine storm, I lost my chance to have children, I ended up having Hashimoto's disease, Degenerative Disc disease, and my body started to shut down during my first trimester. I am 6ft tall and got down to 119lbs. My husband and I went to a special immunologist in Terrace, California. They took 17 vials of blood as we flew there for a day and returned home that evening. In 3 weeks, we had the answer, I have Celiac disease. Once this was known, only my father and husband made efforts to change their way of feeding me. At the family cabin, my stepfather & mother were more worried that I would ruin Thanksgiving Dinner. It wasn't until one of my cousins was diagnosed with Celiac disease. They finally looked into getting Gluten Free flour and taking measures to limit "gluten" in meals. He did nothing but ask for me to pay for my own food and wi-fi when I came to the cabin to stay after our house burned down. When he informed my mother, they proceeding to get into a physical fight and she ended up with a black eye. The is just more trauma for me. Sam had no interest in telling the truth about what he wanted. He lied to my mother that he had asked my husband if I could pay for "food" when he asked Geoffrey if I had money to pay for my wi-fi. My mother hates when he spends so much time on the computer so he lied and said I could pay for my own food. I will remind you I weighed 119lbs at this time. (At 6ft) that is a very sick looking person. Neither parent was worried about my weight, they just fought about how cheap my stepfather was. As my mother was diagnosed with Alzheimer's disease in 2014. He had her sign over the will to a trust and added his children. He had no testimonial capacity at the time, so she signed without proper papers. Making this Trust null and void. When I gave my brother my childhood home, my mother stated I would be getting an equal part of inheritance to the house on Race. It currently worth 2.0 million $. I got nothing, and my stepfather has since disowned me b/c of my claim and he knows that my mother would never have left it uneven between my biological brother and myself. She sat me and my husband down, as we lived at the Race Street house and treated and took care of it as our own. My brother took over b/c he was going through a horrific divorce and needed a home so he could get a better custody deal with his soon to be ex-wife who was a Assist DA for Denver. She used the girls against him, and he & I were the primary caregivers. We, Judd and I spent the most time with them pre the divorce. Once Judd moved into the house, he threw all of my mother, grandmother and my family heirlooms out to the Goodwill. Nobody told my mother about this as she was going through cancer treatment and had Alzheimer's disease in her mother and her sister. My stepfather and biological brother took advantage of this matter, as I called a "family council" that my brother just never could make it to at the last moment. All of the furnishing, kitchen ware, everything was in the house my brother just moved into. He had had 2 weddings, I chose to elope b/c my stepfather ruined my brother's first wedding by talking about his relationship with my brother in front of my dad and his entire family, insulting him and having my grandfather leave the ceremony. It was a disaster. My stepfather just plays dumb and blames my father for the slight. I was the only child not to have a wedding. So, my mother and stepfather never had to pay for a thing. My mother had had an agreement with my father he'd pay for college and all medical issues with their kids, myself and Judd. So truly my mother never had to pay for anything big for me in her entire life. I am looking for anyone that has had a similar story, where they grew up in a household that had a baker that regularly milled flour and ate gluten. What happened to you? DId you suffer from different auto-immune diseases b/c of living with a baker using "gluten" Please let me know. I have been looking into legal ways to get my stepfather to give me what my mother had promised, and he erased. Thank you for listening to my story. Jane Donnelly  
    • trents
      Blood results

      By trents · Posted

      Possibly gluten withdrawal. Lot's of info on the internet about it. Somewhat controversial but apparently gluten plugs into the same neuro sensors as opiates do and some people get a similar type withdrawal as they do when quitting opiates. Another issue is that gluten-free facsimile flours are not fortified with vitamins and minerals as is wheat flour (in the U.S. at least) so when the switch is made to gluten-free facsimile foods, especially if a lot of processed gluten-free foods are being used as substitutes, vitamin and mineral deficiencies can result. There is also the possibility that she has picked up a virus or some but that is totally unrelated to going gluten-free.
×
×
  • Create New...