Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Interesting Article On Gluten/casein Sensitivity


CMCM

Recommended Posts

CMCM Rising Star

I found this article...kind of thought-provoking overall. After reading the info on celiac and Ireland, and also the link the schizophrenia, I have to wonder about my father in law, who was Irish and schizophrenic.

_________

One of the deep mysteries of our time is the question of why, with living standards higher than ever before in history, so many people in the “developed” world are disabled by chronic fatigue syndrome, depression, ADD, autism, irritable bowl syndrome, psoriasis, hyperactivity and related disorders. The numbers are startling, showing significant jumps, for example, in depression for each age cohort born after World War II.

Americans now in their seventies came of age during the Great Depression and World War II, with great attendant social and emotional trauma. But they had very few depressive illnesses. Baby boomers, born to great prosperity and opportunity, suffered so much affective disorder that their ill fated attempts to live better through chemistry launched a drug culture. And Gen-X’ers (as the boomers’ children call themselves) have taken depressive and affective disorders exponential.

Hyperactivity is a disorder not yet 30 years old, but already some 20% or more of school children are deemed to have it. “Chronic fatigue syndrome” came into being right alongside “yuppie”, (remember it used to be the yuppie flu?) in the 1980’s. And ADD is really a 90’s thing. It would be nice to think that Ciba Geigy created it in order to sell Ritalin, but unfortunately that’s hardly the case. A lot of kids and grownups are seriously afflicted with “brain fog.”

An intriguing new theory on the cause of this epidemic of misery implicates evolutionary biology, modern medical miracles and industrialized food production. In its essence the theory proposes that, for very complex reasons, our basic foodstuffs may be slowly poisoning us.

Casein and gluten, proteins in milk and grain, have a strikingly similar molecular structure. Research underway at university medical centers worldwide indicates that certain individuals, particularly those from Ireland, and Scotland, and their descendants in places like Canada, may be so sensitive to these compounds that dietary overloads can damage the digestive tract and, eventually, the central nervous system.

Dietary gluten is already recognized as the cause of celiac disease. But new research points to gluten intolerance as a possible causative agent of schizophrenia, autism, multiple sclerosis and depression. Dr. Kalle Reichelt of the Institute of Pediatric Research at the University of Oslo in Norway cited over 200 international scholarly sources in a 1996 paper advancing the theory that schizophrenia and related affective disorders are caused by “food constituents (gluten and casein) (that) may have disease-promoting effects and cause behavioral changes.”

The theory originated in the 1960’s with an American, Dr. Curtis Dohan. He put schizophrenics on gluten-free, casein free diets under double blind conditions and got dramatic results. Many of his patients were able to return home from locked mental hospital wards.

Later studies provided conflicting information, but Dohan, who began his investigations because he knew of mental disturbance in celiac disease, argued that other researchers gave up too soon. Because damaged intestinal mucosa must be given time to heal, Dohan said, the diet should be maintained for at least six months before results are assessed.

Reichelt, in Norway, has recently used new methodology to validate Dohan’s theory. Reichelt achieved dramatic learning and behavior improvements in autistic children with a gluten-casein free diet.

According to Reichelt and others, individuals who lack the ability to completely digest gluten and casein end up with errant biologically active peptides in the intestine and the bloodstream. These peptides damage the intestinal wall, setting the stage for food allergies and malabsorption/ malnutrition syndromes. Stress and other factors play various roles, but some gluten and casein peptides get through the blood brain-barrier and disrupt normal brain function.

Reichelt and others found incompletely digested proteins in the urine of children with behavioral disorders. Apparently these “nasty proteins”, gluten and casein, are “opioids”, similar to morphine. They cause havoc in the brain by competing for endorphin (read “feel good”) receptors.

The body responds to these “foreign invaders” as if they were viral, with an inflammatory response, according to the theory. But there is no virus, so the body attacks itself. Over time the central nervous system is damaged, possibly setting the stage for degenerative diseases such as multiple sclerosis. How does this become a disease of modern civilization?

Rice, millet, sorghum, tubers and corn, the foods of the third world, do not contain gluten. But industrialized societies, in the late 20th century, consume primarily wheat, a gluten-containing grain. The practice of cultivating gluten grains (wheat, barley, oats, and rye) began 10,000 years ago in the Middle East and slowly spread through Europe, finally reaching Ireland in 3000 BC. Even today, high rates of celiac disease and schizophrenia in western Ireland hint that many have not fully adapted to glutens.

And, over the past 200 years, humans have fiddled with genetic selection of wheat, greatly enriching its gluten content. Today 50% of the protein in wheat is gluten, a characteristic that facilitates bread baking and adapts the grain well to cultivation and harvesting. Is this a cautionary tale about the unexpected consequences of genetically engineered foods?

Reichelt feels that our diverse modern diet, which relies less on grain than it did even 100 years ago (remember porridge?) results in slow degenerative diseases in sensitive individuals. Chronic depression, chronic fatigue syndrome, ADD, hyperactivity, and other “affective disorders”, may be mixed or hybrid forms, “subsets” of the major neurological disturbances that researchers identify with gluten-casein sensitivity.

But why the sudden “ramping up” of diseases like depression in the past 50 years? Maybe the infection-prone babies whose lives were saved by antibiotics since World War II became the depressed, fatigued and anxious adults of the 90’s. If gluten/casein sensitivity was the underlying cause of a child’s immune problems, one could theorize that it might underly later bouts of depression, ADD, hyperactivity, etc. Today’s senior citizens, on the other hand, survived a time when, typically, vulnerable babies didn’t make it to adulthood.

Perhaps 25 years from now people will say; “Can you imagine, they had no idea that wheat and milk could affect brain function? And all those people sleeping on their streets and filling up their prisons!” It seems foolish… but, then,… it wasn’t so long ago that germ theory and handwashing emerged to save the lives of millions of women who otherwise would have died in childbirth.

THE GLUTEN & DAIRY FREE DIET

DON’T EAT

Cow’s milk in any form….no cheese, no milk, no yogurt, no ice cream, no butter. What you are doing here is avoiding casein, the protein in cow’s milk…lactose free products don’t address the problem of casein intolerance. The one exception to this rule found is ghee or clarified butter. Because the process involved in making ghee, which is clarified butter, involves removing the milk proteins, it appears that this form of butter is acceptable. It is probably a healthier food than hydrogenated margarines, so this has been good news.

ALSO DON’T EAT

Gluten in any form…this means anything made from the gluten grains, wheat rye, oats and barley. Also no kamut, spelt, as these are also gluten grains. This rules out most commercial breads, pastas and most commercial baked goods. Also Chinese noodles and anything that is breaded (like “fish n’ chips” ) before frying are gluten foods. But rice pasta is great…most Thai food is O.K. because their cuisine emphasizes rice noodles Hidden glutens occur in imitation crab (as in California roll sushi), in soy sauce (substitute wheat free tamari sauce), in packaged foods containing hydrolyzed vegetable protein and malt extracts (Sorry, this includes beer).

O.K. TO EAT

All fruits

All vegetables

All eggs

All meats

All fish

All beans

Corn

Rice

Potatoes

Quinoa

Buckwheat

Amaranth

Coffee, tea, wine, brandy


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



danikali Enthusiast

How do I know if I'm casein intolerant? I've been going on and off the dairy for a few weeks now and have not noticed any major changes, if any at all.....but on the other hand, I don't want to be sacrificing my immune system only sticking to the gluten free diet but eating casein! I'm kind of scared here because I've had SEVERE depression before, and if casein can cause that, and I'm sensitive to it, then I'll def. stay away from it. But if it doesn't affect me like the gluten, then I don't want to deprive myself more than I already am! My cravings for dairy are insane when I go off of it and I end up overeating everything else! Any advice?

nettiebeads Apprentice

Thank you very much for the time and effort you put in to your research. You definitely get a gold star for today! :)

Annette

Mango04 Enthusiast
How do I know if I'm casein intolerant? I've been going on and off the dairy for a few weeks now and have not noticed any major changes, if any at all.....but on the other hand, I don't want to be sacrificing my immune system only sticking to the gluten free diet but eating casein! I'm kind of scared here because I've had SEVERE depression before, and if casein can cause that, and I'm sensitive to it, then I'll def. stay away from it. But if it doesn't affect me like the gluten, then I don't want to deprive myself more than I already am! My cravings for dairy are insane when I go off of it and I end up overeating everything else! Any advice?

I've read that you crave the foods you are intolerant and/or allergic to. Maybe you could try to remain completely 100% casein free for atleast a month (maybe longer) and then reintroduce it and see if you notice any differences. I think it's hard to tell what's really happening when you go on and off it - I believe you need to stay CF for a pretty significant amount of time for a self diagnosis to work (that's my experience anyway). Your cravings might subside once the casein has completely left your system. Maybe you could try Enterolab if you're still unsure?

Nancym Enthusiast

I wonder if the high rate of food intolerances is because there was a period where doctors were encouraging women to NOT breastfeed. In fact, my own mother didn't breastfeed any of us because doctors were telling them that formula was healthier. *sigh*

Nevadan Contributor
I found this article...kind of thought-provoking overall. After reading the info on celiac and Ireland, and also the link the schizophrenia, I have to wonder about my father in law, who was Irish and schizophrenic.

Carole,

A very interesting article. Could you please post it's source? Thanks.

George

Claire Collaborator

I found this article...kind of thought-provoking overall. After reading the info on celiac and Ireland, and also the link the schizophrenia, I have to wonder about my father in law, who was Irish and schizophrenic.

_________

Thanks for this post. Did you get it from the internet? If so do you have a URL for it? Thanks. Claire


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



CMCM Rising Star
How do I know if I'm casein intolerant? I've been going on and off the dairy for a few weeks now and have not noticed any major changes, if any at all.....but on the other hand, I don't want to be sacrificing my immune system only sticking to the gluten free diet but eating casein! I'm kind of scared here because I've had SEVERE depression before, and if casein can cause that, and I'm sensitive to it, then I'll def. stay away from it. But if it doesn't affect me like the gluten, then I don't want to deprive myself more than I already am! My cravings for dairy are insane when I go off of it and I end up overeating everything else! Any advice?

Well, my feeling from my own experience was that I had major and identifiable trouble with dairy my entire life. So finding out I was casein intolerant wasn't a surprise. If you don't have symptoms, it may not be an issue for you. It's not for everyone. My mom had the worse possible, classic case of celiac and nearly died before she was diagnosed....and she does not appear to have any problems whatsoever with dairy and never has.

As for testing, you can get it done via Enterolab. I did their complete panel which tested not only the genes, but the celiac/gluten sensitivity, and also for casein thrown in as well. I believe you can do the casein one separately, too. You'd have to check with Enterolab.

Carole

arial12bold Rookie

I think the article comes from this website >> Open Original Shared Link

The homepage is this >> Open Original Shared Link

arial

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - knitty kitty replied to hjayne19's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      15

      Insomnia help

    2. - TheDHhurts posted a topic in Gluten-Free Foods, Products, Shopping & Medications
      0

      need help understanding testing result for Naked Nutrition Creatine please

    3. - cristiana replied to hjayne19's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      15

      Insomnia help

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,107
    • Most Online (within 30 mins)
      7,748

    Maggie1349
    Newest Member
    Maggie1349
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Who's Online (See full list)

    • There are no registered users currently online
  • Upcoming Events

  • Posts

    • knitty kitty
      @cristiana,  I react the same way.  Dairy consumption flushes out my digestive system within an hour, too! As casein is digested, it forms casomorphins that bind to opioid receptors in our bodies.  This is similar to digested gluten peptides being able to attach to opioid receptors in our bodies.   We have opioid receptors throughout our bodies including lots in the digestive tract. Casein raises tTg IgA antibodies just like gluten consumption does, which leads to further intestinal damage and continuing inflammation.  No wonder our bodies react to it by pushing the "emergency evacuation" ejection seat button! The mother of my childhood friend was British and introduced me to drinking tea properly with milk or cream.  I miss it so much.  And chocolate ice cream.  Not worth the after effects, though.  I've found taking Omega Three supplements (flaxseed oil, sunflower seed oil, evening primrose oil) helps shake those dairy cravings.   Green leafy veggies like broccoli, kale, and greens (mustard, turnip, collards) are great sources of calcium.  Avoid spinach as it is high in oxalates that block calcium absorption and may cause kidney stones.  Yes, more leafy greens are needed to reach the same amount of calcium in a glass of milk, but the greens have other benefits, like increased dietary fiber and polyphenols that act as antioxidants, reduce inflammation, and promote health.   Exposure to gluten (and casein in those sensitive to it) can cause an increased immune response and inflammation for months afterwards.  The immune cells that make tTg IgA antibodies which are triggered today are going to live for about two years. During that time, inflammation is heightened.  Those immune cells only replicate when triggered.  If those immune cells don't get triggered again for about two years, they die without leaving any descendents programmed to trigger on gluten and casein.  The immune system forgets gluten and casein need to be attacked.  The Celiac genes turn off.  This is remission.   Some people in remission report being able to consume gluten again without consequence.  Another triggering event can turn the Celiac genes on again.   Celiac genes are turned on by a triggering event (physical or emotional stress).  There's some evidence that thiamine insufficiency contributes to the turning on of autoimmune genes.  There is an increased biological need for thiamine when we are physically or emotionally stressed.  Thiamine cannot be stored for more than twenty-one days and may be depleted in as little as three during physical and emotional stresses. Mitochondria without sufficient thiamine become damaged and don't function properly.  This gets relayed to the genes and autoimmune disease genes turn on.  Thiamine and other B vitamins, minerals, and other nutrients are needed to replace the dysfunctional mitochondria and repair the damage to the body.  
    • TheDHhurts
      Hi, I bought Naked Nutrition Creatine. It lists itself as gluten free but is not certified. (It used to be, but they dropped it in the past year or two apparently.) I wrote the company and asked them what testing results they had for creatine and they sent me the attached, which says the test result for gluten is <0.025MCG. I'm used to seeing test results as ppm, so I'm not sure what <0.025MCG means. Can it be converted to ppm easily? I want to confirm that it is safe to use.
    • cristiana
      When I was still recovering my gastroenterologist suggested I bought lactofree product as I was very bloated.  So I bought some from the supermarket and from memory, I drank a nice big glass of milk - and it went right through me literally within an hour or so, if my memory serves correctly.  I came off dairy completely next and it worked like a charm, but started to reintroduce quite gradually it as I missed it! To this day, if I overdo dairy products, they work like a mild laxative.  I've never wanted to give up milk completely as I like it so much, and my mum had osteoporosis and it's an easy way of getting calcium.  But it doesn't really 'sit' well with me.   You may need to experiment a bit as when I was healing certain dairy products were worse than others - I could cope with one brand of Greek yoghurt, but I got extremely and painfully bloated with another brand of live British yoghurt.  
    • wellthatsfun
      i have been strictly gluten free for 7 months. this includes avoiding anything that may contain gluten and making sure surfaces and appliances are clean. i am 18 years old in australia and my tTG-IgA results were 69U/mL, pretty low compared to most people's, for reference. i feel the exact same as before. sure, i was pretty much asymptomatic/silent. the worst i'd get was occasionally bad stools and pitting of the nails/brittle hair since early childhood - and i was diagnosed with low iron and vitamin d which checks out due to easy bruising and such. but those symptoms have remained. maybe i'm jumping the gun, sure. i know it can take years to fully heal. but being over half a year in, i feel that i should be, y'know, healing. i'm nearly at my wits end and wondering if i should have a piece of bread or something to see how i go - to see if i possibly have refractory? my mental health is declining as i feel myself wanting to bang my head against a damn wall out of frustration every day. cravings haven't gotten better. look, i love the stuff i still can have, like salads and such. OH! i haven't lost any weight, which is mind boggling considering i eat very healthily now! i've always been on the chubbier side which is atypical of coeliac. i just don't know what's going on with me. i try to remain hopeful but i'm just so sad all the time. thanks for reading  
    • trents
      @Charlie1946There is a PM (Personal Message) tool built into the forum website that allows you to send a private message to other forum users. Just hover over their name with your mouse cursor and the menu containing that tool will pop up. This is useful if you want to communicate with an individual without everyone else involved in the thread seeing it.  Are you realizing that in my PPI taper down recommendations in an earlier post above, I was responding not to your posts but to @Caligirl57? If you must use a PPI, I certainly would advise taking the lowest dose that is effective for you.  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.